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Items: 1 to 20 of 206

1.

Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway.

Nimmo ER, Prendergast JG, Aldhous MC, Kennedy NA, Henderson P, Drummond HE, Ramsahoye BH, Wilson DC, Semple CA, Satsangi J.

Inflamm Bowel Dis. 2012 May;18(5):889-99. doi: 10.1002/ibd.21912. Epub 2011 Oct 21.

PMID:
22021194
2.

Two-stage genome-wide methylation profiling in childhood-onset Crohn's Disease implicates epigenetic alterations at the VMP1/MIR21 and HLA loci.

Adams AT, Kennedy NA, Hansen R, Ventham NT, OʼLeary KR, Drummond HE, Noble CL, El-Omar E, Russell RK, Wilson DC, Nimmo ER, Hold GL, Satsangi J.

Inflamm Bowel Dis. 2014 Oct;20(10):1784-93. doi: 10.1097/MIB.0000000000000179.

3.

Hurdles for epigenetic disease associations from peripheral blood leukocytes.

Kellermayer R.

Inflamm Bowel Dis. 2013 Apr;19(5):E66-7. doi: 10.1097/MIB.0b013e318280eca4. No abstract available.

PMID:
23314245
4.

Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status.

Schmechel S, Konrad A, Diegelmann J, Glas J, Wetzke M, Paschos E, Lohse P, Göke B, Brand S.

Inflamm Bowel Dis. 2008 Feb;14(2):204-12.

PMID:
18022867
5.

Genome-wide DNA methylation analysis in alcohol dependence.

Zhang R, Miao Q, Wang C, Zhao R, Li W, Haile CN, Hao W, Zhang XY.

Addict Biol. 2013 Mar;18(2):392-403. doi: 10.1111/adb.12037. Epub 2013 Feb 7.

PMID:
23387924
6.

Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD.

Seiderer J, Elben I, Diegelmann J, Glas J, Stallhofer J, Tillack C, Pfennig S, Jürgens M, Schmechel S, Konrad A, Göke B, Ochsenkühn T, Müller-Myhsok B, Lohse P, Brand S.

Inflamm Bowel Dis. 2008 Apr;14(4):437-45.

PMID:
18088064
7.

Monocyte-derived dendritic cells from Crohn's disease patients exhibit decreased ability to activate T helper type 17 responses in memory cells.

Nieminen JK, Sipponen T, Färkkilä M, Vaarala O.

Clin Exp Immunol. 2014 Jul;177(1):190-202. doi: 10.1111/cei.12326.

8.

Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlations with pathogenesis.

Waterman M, Xu W, Stempak JM, Milgrom R, Bernstein CN, Griffiths AM, Greenberg GR, Steinhart AH, Silverberg MS.

Inflamm Bowel Dis. 2011 Sep;17(9):1936-42. doi: 10.1002/ibd.21579. Epub 2010 Dec 10.

9.

Mucosal genome-wide methylation changes in inflammatory bowel disease.

Cooke J, Zhang H, Greger L, Silva AL, Massey D, Dawson C, Metz A, Ibrahim A, Parkes M.

Inflamm Bowel Dis. 2012 Nov;18(11):2128-37. doi: 10.1002/ibd.22942. Epub 2012 Mar 14.

PMID:
22419656
10.

Characterization of intestinal gene expression profiles in Crohn's disease by genome-wide microarray analysis.

Noble CL, Abbas AR, Lees CW, Cornelius J, Toy K, Modrusan Z, Clark HF, Arnott ID, Penman ID, Satsangi J, Diehl L.

Inflamm Bowel Dis. 2010 Oct;16(10):1717-28. doi: 10.1002/ibd.21263.

PMID:
20848455
11.

Genome-wide profiling of methylation identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes.

del Rey M, O'Hagan K, Dellett M, Aibar S, Colyer HA, Alonso ME, Díez-Campelo M, Armstrong RN, Sharpe DJ, Gutiérrez NC, García JL, De Las Rivas J, Mills KI, Hernández-Rivas JM.

Leukemia. 2013 Mar;27(3):610-8. doi: 10.1038/leu.2012.253. Epub 2012 Aug 31.

PMID:
22936014
12.

Identification of disease-associated DNA methylation in B cells from Crohn's disease and ulcerative colitis patients.

Lin Z, Hegarty JP, Yu W, Cappel JA, Chen X, Faber PW, Wang Y, Poritz LS, Fan JB, Koltun WA.

Dig Dis Sci. 2012 Dec;57(12):3145-53. doi: 10.1007/s10620-012-2288-z. Epub 2012 Jul 21.

PMID:
22821069
13.

Crohn's disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy.

Scharl M, Mwinyi J, Fischbeck A, Leucht K, Eloranta JJ, Arikkat J, Pesch T, Kellermeier S, Mair A, Kullak-Ublick GA, Truninger K, Noreen F, Regula J, Gaj P, Pittet V, Mueller C, Hofmann C, Fried M, McCole DF, Rogler G.

Inflamm Bowel Dis. 2012 May;18(5):900-12. doi: 10.1002/ibd.21913. Epub 2011 Oct 21.

PMID:
22021207
14.

Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease.

Török HP, Glas J, Endres I, Tonenchi L, Teshome MY, Wetzke M, Klein W, Lohse P, Ochsenkühn T, Folwaczny M, Göke B, Folwaczny C, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2009 Jul;104(7):1723-33. doi: 10.1038/ajg.2009.184. Epub 2009 May 19.

PMID:
19455129
15.

Pathway analysis of a genome-wide association study of ileal Crohn's disease.

Lee YH, Song GG.

DNA Cell Biol. 2012 Oct;31(10):1549-54. Epub 2012 Sep 7.

PMID:
22957492
16.

Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.

Agardh E, Lundstig A, Perfilyev A, Volkov P, Freiburghaus T, Lindholm E, Rönn T, Agardh CD, Ling C.

BMC Med. 2015 Aug 6;13:182. doi: 10.1186/s12916-015-0421-5.

17.

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.

Yamazaki K, Umeno J, Takahashi A, Hirano A, Johnson TA, Kumasaka N, Morizono T, Hosono N, Kawaguchi T, Takazoe M, Yamada T, Suzuki Y, Tanaka H, Motoya S, Hosokawa M, Arimura Y, Shinomura Y, Matsui T, Matsumoto T, Iida M, Tsunoda T, Nakamura Y, Kamatani N, Kubo M.

Gastroenterology. 2013 Apr;144(4):781-8. doi: 10.1053/j.gastro.2012.12.021. Epub 2012 Dec 22.

PMID:
23266558
18.

Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease.

van Heel DA, Ghosh S, Hunt KA, Mathew CG, Forbes A, Jewell DP, Playford RJ.

Gut. 2005 Nov;54(11):1553-7. Epub 2005 May 31.

19.

Autophagy gene ATG16L1 influences susceptibility and disease location but not childhood-onset in Crohn's disease in Northern Europe.

Van Limbergen J, Russell RK, Nimmo ER, Drummond HE, Smith L, Anderson NH, Davies G, Gillett PM, McGrogan P, Weaver LT, Bisset WM, Mahdi G, Arnott ID, Wilson DC, Satsangi J.

Inflamm Bowel Dis. 2008 Mar;14(3):338-46.

PMID:
18088053
20.

Association of polymorphisms in the interleukin-18 gene in patients with Crohn's disease depending on the CARD15/NOD2 genotype.

Glas J, Török HP, Tonenchi L, Kapser J, Schiemann U, Müller-Myhsok B, Folwaczny M, Folwaczny C.

Inflamm Bowel Dis. 2005 Dec;11(12):1031-7.

PMID:
16306764
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