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Results: 1 to 20 of 113

1.

F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest.

Chen BB, Glasser JR, Coon TA, Mallampalli RK.

Oncogene. 2012 May 17;31(20):2566-79. doi: 10.1038/onc.2011.432. Epub 2011 Oct 24.

PMID:
22020328
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

FBXL2 is a ubiquitin E3 ligase subunit that triggers mitotic arrest.

Chen BB, Glasser JR, Coon TA, Mallampalli RK.

Cell Cycle. 2011 Oct 15;10(20):3487-94. doi: 10.4161/cc.10.20.17742. Epub 2011 Oct 15.

PMID:
22024926
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

F-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferation.

Chen BB, Glasser JR, Coon TA, Zou C, Miller HL, Fenton M, McDyer JF, Boyiadzis M, Mallampalli RK.

Blood. 2012 Mar 29;119(13):3132-41. doi: 10.1182/blood-2011-06-358911. Epub 2012 Feb 8.

PMID:
22323446
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis.

Chen BB, Glasser JR, Coon TA, Mallampalli RK.

Cell Death Dis. 2013 Aug 8;4:e759. doi: 10.1038/cddis.2013.271.

PMID:
23928698
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis.

Chen BB, Coon TA, Glasser JR, Mallampalli RK.

Mol Cell Biol. 2011 May;31(9):1905-20. doi: 10.1128/MCB.00723-10. Epub 2011 Feb 22.

PMID:
21343341
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation.

D'Angiolella V, Donato V, Vijayakumar S, Saraf A, Florens L, Washburn MP, Dynlacht B, Pagano M.

Nature. 2010 Jul 1;466(7302):138-42. doi: 10.1038/nature09140.

PMID:
20596027
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest.

Coon TA, Glasser JR, Mallampalli RK, Chen BB.

Cell Cycle. 2012 Feb 15;11(4):721-9. doi: 10.4161/cc.11.4.19171. Epub 2012 Feb 15.

PMID:
22306998
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.

Nature. 2011 Mar 3;471(7336):104-9. doi: 10.1038/nature09732.

PMID:
21368833
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex.

Lin DI, Barbash O, Kumar KG, Weber JD, Harper JW, Klein-Szanto AJ, Rustgi A, Fuchs SY, Diehl JA.

Mol Cell. 2006 Nov 3;24(3):355-66.

PMID:
17081987
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The novel ubiquitin ligase complex, SCF(Fbxw4), interacts with the COP9 signalosome in an F-box dependent manner, is mutated, lost and under-expressed in human cancers.

Lockwood WW, Chandel SK, Stewart GL, Erdjument-Bromage H, Beverly LJ.

PLoS One. 2013 May 2;8(5):e63610. doi: 10.1371/journal.pone.0063610. Print 2013.

PMID:
23658844
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.

Bornstein G, Ganoth D, Hershko A.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11515-20. Epub 2006 Jul 21.

PMID:
16861300
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation.

Zhao J, Mialki RK, Wei J, Coon TA, Zou C, Chen BB, Mallampalli RK, Zhao Y.

FASEB J. 2013 Jul;27(7):2611-9. doi: 10.1096/fj.12-223099. Epub 2013 Mar 19.

PMID:
23512198
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.

Xu Y, Sengupta T, Kukreja L, Minella AC.

J Biol Chem. 2010 Nov 5;285(45):34439-46. doi: 10.1074/jbc.M110.152306. Epub 2010 Sep 7.

PMID:
20826802
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Polyubiquitination of the B-cell translocation gene 1 and 2 proteins is promoted by the SCF ubiquitin ligase complex containing βTrCP.

Sasajima H, Nakagawa K, Kashiwayanagi M, Yokosawa H.

Biol Pharm Bull. 2012;35(9):1539-45.

PMID:
22975506
[PubMed - indexed for MEDLINE]
Free Article
15.

F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage.

Santra MK, Wajapeyee N, Green MR.

Nature. 2009 Jun 4;459(7247):722-5. doi: 10.1038/nature08011. Epub 2009 May 3.

PMID:
19412162
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The centrosomal E3 ubiquitin ligase FBXO31-SCF regulates neuronal morphogenesis and migration.

Vadhvani M, Schwedhelm-Domeyer N, Mukherjee C, Stegmüller J.

PLoS One. 2013;8(2):e57530. doi: 10.1371/journal.pone.0057530. Epub 2013 Feb 28.

PMID:
23469015
[PubMed - indexed for MEDLINE]
Free PMC Article
17.
18.

Betulinic acid decreases specificity protein 1 (Sp1) level via increasing the sumoylation of sp1 to inhibit lung cancer growth.

Hsu TI, Wang MC, Chen SY, Huang ST, Yeh YM, Su WC, Chang WC, Hung JJ.

Mol Pharmacol. 2012 Dec;82(6):1115-28. doi: 10.1124/mol.112.078485. Epub 2012 Sep 5.

PMID:
22956772
[PubMed - indexed for MEDLINE]
Free Article
19.

The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation.

Vaites LP, Lee EK, Lian Z, Barbash O, Roy D, Wasik M, Klein-Szanto AJ, Rustgi AK, Diehl JA.

Mol Cell Biol. 2011 Nov;31(22):4513-23. doi: 10.1128/MCB.05733-11. Epub 2011 Sep 12.

PMID:
21911473
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.

Sun L, Shi L, Li W, Yu W, Liang J, Zhang H, Yang X, Wang Y, Li R, Yao X, Yi X, Shang Y.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10195-200. doi: 10.1073/pnas.0901864106. Epub 2009 Jun 9.

PMID:
19509332
[PubMed - indexed for MEDLINE]
Free PMC Article

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