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Items: 1 to 20 of 168

1.

Protein arginine methyltransferase Prmt5-Mep50 methylates histones H2A and H4 and the histone chaperone nucleoplasmin in Xenopus laevis eggs.

Wilczek C, Chitta R, Woo E, Shabanowitz J, Chait BT, Hunt DF, Shechter D.

J Biol Chem. 2011 Dec 9;286(49):42221-31. doi: 10.1074/jbc.M111.303677. Epub 2011 Oct 18.

2.

Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.

Burgos ES, Wilczek C, Onikubo T, Bonanno JB, Jansong J, Reimer U, Shechter D.

J Biol Chem. 2015 Apr 10;290(15):9674-89. doi: 10.1074/jbc.M115.636894. Epub 2015 Feb 24.

3.

Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.

Ho MC, Wilczek C, Bonanno JB, Xing L, Seznec J, Matsui T, Carter LG, Onikubo T, Kumar PR, Chan MK, Brenowitz M, Cheng RH, Reimer U, Almo SC, Shechter D.

PLoS One. 2013;8(2):e57008. doi: 10.1371/journal.pone.0057008. Epub 2013 Feb 25. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/e6b5348e-9052-4a3b-8f06-90d01dc88fc2.

4.

Phosphorylation and arginine methylation mark histone H2A prior to deposition during Xenopus laevis development.

Wang WL, Anderson LC, Nicklay JJ, Chen H, Gamble MJ, Shabanowitz J, Hunt DF, Shechter D.

Epigenetics Chromatin. 2014 Sep 6;7:22. doi: 10.1186/1756-8935-7-22. eCollection 2014.

5.

Nucleoplasmin-mediated unfolding of chromatin involves the displacement of linker-associated chromatin proteins.

Ramos I, Prado A, Finn RM, Muga A, Ausió J.

Biochemistry. 2005 Jun 14;44(23):8274-81.

PMID:
15938617
6.

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.

Pal S, Vishwanath SN, Erdjument-Bromage H, Tempst P, Sif S.

Mol Cell Biol. 2004 Nov;24(21):9630-45.

8.

Chromatin decondensation and nuclear reprogramming by nucleoplasmin.

Tamada H, Van Thuan N, Reed P, Nelson D, Katoku-Kikyo N, Wudel J, Wakayama T, Kikyo N.

Mol Cell Biol. 2006 Feb;26(4):1259-71. Erratum in: Mol Cell Biol. 2007 Sep;27(18):6580.

9.

MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.

Saha K, Adhikary G, Eckert RL.

J Invest Dermatol. 2016 Jan;136(1):214-24. doi: 10.1038/JID.2015.400.

10.

Interaction of nucleoplasmin with core histones.

Arnan C, Saperas N, Prieto C, Chiva M, Ausió J.

J Biol Chem. 2003 Aug 15;278(33):31319-24. Epub 2003 Jun 5.

11.

Human protein arginine methyltransferase 7 (PRMT7) is a type III enzyme forming ω-NG-monomethylated arginine residues.

Zurita-Lopez CI, Sandberg T, Kelly R, Clarke SG.

J Biol Chem. 2012 Mar 9;287(11):7859-70. doi: 10.1074/jbc.M111.336271. Epub 2012 Jan 12.

12.

Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion.

Wang M, Fuhrmann J, Thompson PR.

Biochemistry. 2014 Dec 23;53(50):7884-92. doi: 10.1021/bi501279g. Epub 2014 Dec 8.

PMID:
25485739
13.

Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene Expression.

Saha K, Eckert RL.

J Biol Chem. 2015 May 22;290(21):13521-30. doi: 10.1074/jbc.M115.642868. Epub 2015 Apr 7.

14.

Nucleoplasmin binds histone H2A-H2B dimers through its distal face.

Ramos I, Martín-Benito J, Finn R, Bretaña L, Aloria K, Arizmendi JM, Ausió J, Muga A, Valpuesta JM, Prado A.

J Biol Chem. 2010 Oct 29;285(44):33771-8. doi: 10.1074/jbc.M110.150664. Epub 2010 Aug 9.

15.

Co-existence of two different types of soluble histone complexes in nuclei of Xenopus laevis oocytes.

Kleinschmidt JA, Fortkamp E, Krohne G, Zentgraf H, Franke WW.

J Biol Chem. 1985 Jan 25;260(2):1166-76.

16.

Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition.

Onikubo T, Nicklay JJ, Xing L, Warren C, Anson B, Wang WL, Burgos ES, Ruff SE, Shabanowitz J, Cheng RH, Hunt DF, Shechter D.

Cell Rep. 2015 Mar 11. pii: S2211-1247(15)00196-5. doi: 10.1016/j.celrep.2015.02.038. [Epub ahead of print]

17.

A mechanism for histone chaperoning activity of nucleoplasmin: thermodynamic and structural models.

Taneva SG, Bañuelos S, Falces J, Arregi I, Muga A, Konarev PV, Svergun DI, Velázquez-Campoy A, Urbaneja MA.

J Mol Biol. 2009 Oct 23;393(2):448-63. doi: 10.1016/j.jmb.2009.08.005. Epub 2009 Aug 13.

PMID:
19683001
18.

The Kruppel-like zinc finger protein ZNF224 recruits the arginine methyltransferase PRMT5 on the transcriptional repressor complex of the aldolase A gene.

Cesaro E, De Cegli R, Medugno L, Florio F, Grosso M, Lupo A, Izzo P, Costanzo P.

J Biol Chem. 2009 Nov 20;284(47):32321-30. doi: 10.1074/jbc.M109.043349. Epub 2009 Sep 9.

19.

Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.

Ancelin K, Lange UC, Hajkova P, Schneider R, Bannister AJ, Kouzarides T, Surani MA.

Nat Cell Biol. 2006 Jun;8(6):623-30. Epub 2006 May 14.

PMID:
16699504
20.

The role of nucleoplasmin in chromatin assembly and disassembly.

Laskey RA, Mills AD, Philpott A, Leno GH, Dilworth SM, Dingwall C.

Philos Trans R Soc Lond B Biol Sci. 1993 Mar 29;339(1289):263-9; discussion 268-9. Review.

PMID:
8098530
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