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Results: 1 to 20 of 113

1.

Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model.

Li J, Hsu HC, Yang P, Wu Q, Li H, Edgington LE, Bogyo M, Kimberly RP, Mountz JD.

Arthritis Rheum. 2012 Apr;64(4):1098-109. doi: 10.1002/art.33423. Epub 2011 Oct 13.

PMID:
22006294
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Death receptor 5-targeted depletion of interleukin-23-producing macrophages, Th17, and Th1/17 associated with defective tyrosine phosphatase in mice and patients with rheumatoid arthritis.

Li J, Yang P, Wu Q, Li H, Ding Y, Hsu HC, Spalding DM, Mountz JD.

Arthritis Rheum. 2013 Oct;65(10):2594-605. doi: 10.1002/art.38057.

PMID:
23818173
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis.

Joosten LA, Lubberts E, Helsen MM, Saxne T, Coenen-de Roo CJ, Heinegård D, van den Berg WB.

Arthritis Res. 1999;1(1):81-91. Epub 1999 Oct 26.

PMID:
11056663
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

CXC chemokine receptor 4 expressed in T cells plays an important role in the development of collagen-induced arthritis.

Chung SH, Seki K, Choi BI, Kimura KB, Ito A, Fujikado N, Saijo S, Iwakura Y.

Arthritis Res Ther. 2010;12(5):R188. doi: 10.1186/ar3158. Epub 2010 Oct 12.

PMID:
20939892
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor β-chain.

Merky P, Batsalova T, Bockermann R, Dzhambazov B, Sehnert B, Burkhardt H, Bäcklund J.

Arthritis Res Ther. 2010;12(4):R155. doi: 10.1186/ar3108. Epub 2010 Aug 3.

PMID:
20682070
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

TRAIL-R2 (DR5) mediates apoptosis of synovial fibroblasts in rheumatoid arthritis.

Ichikawa K, Liu W, Fleck M, Zhang H, Zhao L, Ohtsuka T, Wang Z, Liu D, Mountz JD, Ohtsuki M, Koopman WJ, Kimberly R, Zhou T.

J Immunol. 2003 Jul 15;171(2):1061-9.

PMID:
12847280
[PubMed - indexed for MEDLINE]
Free Article
7.

Anti-DR5 mAb ameliorate adjuvant arthritis rats through inducing synovial cells apoptosis.

Li W, Liu Z, Zhuang G, Yin P, Tao H, Qiu J, Hu Q, Zhang J.

Exp Biol Med (Maywood). 2009 Dec;234(12):1468-76. doi: 10.3181/0811-RM-342.

PMID:
19934367
[PubMed - indexed for MEDLINE]
8.

Treatment with anti-gamma-glutamyl transpeptidase antibody attenuates osteolysis in collagen-induced arthritis mice.

Ishizuka Y, Moriwaki S, Kawahara-Hanaoka M, Uemura Y, Serizawa I, Miyauchi M, Shibata S, Kanaya T, Takata T, Taniguchi N, Niida S.

J Bone Miner Res. 2007 Dec;22(12):1933-42.

PMID:
17680722
[PubMed - indexed for MEDLINE]
9.

Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11.

Oliver PG, LoBuglio AF, Zinn KR, Kim H, Nan L, Zhou T, Wang W, Buchsbaum DJ.

Clin Cancer Res. 2008 Apr 1;14(7):2180-9. doi: 10.1158/1078-0432.CCR-07-1392.

PMID:
18381960
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis.

Put S, Schoonooghe S, Devoogdt N, Schurgers E, Avau A, Mitera T, D'Huyvetter M, De Baetselier P, Raes G, Lahoutte T, Matthys P.

J Nucl Med. 2013 May;54(5):807-14. doi: 10.2967/jnumed.112.111781. Epub 2013 Feb 27.

PMID:
23447654
[PubMed - indexed for MEDLINE]
Free Article
11.

Long-term amelioration of established collagen-induced arthritis achieved with short-term therapy combining anti-CD3 and anti-tumor necrosis factor treatments.

Dépis F, Hatterer E, Lamacchia C, Waldburger JM, Gabay C, Reith W, Kosco-Vilbois M, Dean Y.

Arthritis Rheum. 2012 Oct;64(10):3189-98. doi: 10.1002/art.34497.

PMID:
22508436
[PubMed - indexed for MEDLINE]
Free Article
12.

Effect of tumor necrosis factor-related apoptosis-inducing ligand on the reduction of joint inflammation in experimental rheumatoid arthritis.

Jin CH, Chae SY, Kim TH, Yang HK, Lee EY, Song YW, Jo DG, Lee KC.

J Pharmacol Exp Ther. 2010 Mar;332(3):858-65. doi: 10.1124/jpet.109.159517. Epub 2009 Nov 20.

PMID:
19933369
[PubMed - indexed for MEDLINE]
Free Article
13.

Blockade of the interleukin-7 receptor inhibits collagen-induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators.

Hartgring SA, Willis CR, Alcorn D, Nelson LJ, Bijlsma JW, Lafeber FP, van Roon JA.

Arthritis Rheum. 2010 Sep;62(9):2716-25. doi: 10.1002/art.27578.

PMID:
20499386
[PubMed - indexed for MEDLINE]
Free Article
14.

Angiopoietin-2 promotes inflammatory activation of human macrophages and is essential for murine experimental arthritis.

Krausz S, Garcia S, Ambarus CA, de Launay D, Foster M, Naiman B, Iverson W, Connor JR, Sleeman MA, Coyle AJ, Hamann J, Baeten D, Tak PP, Reedquist KA.

Ann Rheum Dis. 2012 Aug;71(8):1402-10. doi: 10.1136/annrheumdis-2011-200718. Epub 2012 Jun 22.

PMID:
22730375
[PubMed - indexed for MEDLINE]
15.

Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis.

Palmer G, Talabot-Ayer D, Lamacchia C, Toy D, Seemayer CA, Viatte S, Finckh A, Smith DE, Gabay C.

Arthritis Rheum. 2009 Mar;60(3):738-49. doi: 10.1002/art.24305.

PMID:
19248109
[PubMed - indexed for MEDLINE]
Free Article
16.

Expression and function of junctional adhesion molecule-C in human and experimental arthritis.

Palmer G, Busso N, Aurrand-Lions M, Talabot-Ayer D, Chobaz-Péclat V, Zimmerli C, Hammel P, Imhof BA, Gabay C.

Arthritis Res Ther. 2007;9(4):R65.

PMID:
17612407
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model.

Buchsbaum DJ, Zhou T, Grizzle WE, Oliver PG, Hammond CJ, Zhang S, Carpenter M, LoBuglio AF.

Clin Cancer Res. 2003 Sep 1;9(10 Pt 1):3731-41.

PMID:
14506165
[PubMed - indexed for MEDLINE]
Free Article
18.

GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis.

van Hamburg JP, Mus AM, de Bruijn MJ, de Vogel L, Boon L, Cornelissen F, Asmawidjaja P, Hendriks RW, Lubberts E.

Arthritis Rheum. 2009 Mar;60(3):750-9. doi: 10.1002/art.24329.

PMID:
19248112
[PubMed - indexed for MEDLINE]
Free Article
19.

Impact of Schistosoma japonicum infection on collagen-induced arthritis in DBA/1 mice: a murine model of human rheumatoid arthritis.

Song X, Shen J, Wen H, Zhong Z, Luo Q, Chu D, Qi Y, Xu Y, Wei W.

PLoS One. 2011;6(8):e23453. doi: 10.1371/journal.pone.0023453. Epub 2011 Aug 8.

PMID:
21858123
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production.

Lo CK, Lam QL, Sun L, Wang S, Ko KH, Xu H, Wu CY, Zheng BJ, Lu L.

Arthritis Rheum. 2008 Sep;58(9):2700-11. doi: 10.1002/art.23760.

PMID:
18759269
[PubMed - indexed for MEDLINE]
Free Article

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