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Items: 1 to 20 of 187

1.

Parthenolide attenuates LPS-induced fever, circulating cytokines and markers of brain inflammation in rats.

Rummel C, Gerstberger R, Roth J, Hübschle T.

Cytokine. 2011 Dec;56(3):739-48. doi: 10.1016/j.cyto.2011.09.022. Epub 2011 Oct 17.

PMID:
22004922
2.

Spatiotemporal nuclear factor interleukin-6 expression in the rat brain during lipopolysaccharide-induced fever is linked to sustained hypothalamic inflammatory target gene induction.

Damm J, Luheshi GN, Gerstberger R, Roth J, Rummel C.

J Comp Neurol. 2011 Feb 15;519(3):480-505. doi: 10.1002/cne.22529.

PMID:
21192080
3.

Parthenolide has limited effects on nuclear factor-kappa beta increases and worsens survival in lipopolysaccharide-challenged C57BL/6J mice.

Li X, Cui X, Li Y, Fitz Y, Hsu L, Eichacker PQ.

Cytokine. 2006 Mar 21;33(6):299-308. Epub 2006 May 23.

PMID:
16720096
4.

The putative JAK-STAT inhibitor AG490 exacerbates LPS-fever, reduces sickness behavior, and alters the expression of pro- and anti-inflammatory genes in the rat brain.

Damm J, Harden LM, Gerstberger R, Roth J, Rummel C.

Neuropharmacology. 2013 Aug;71:98-111. doi: 10.1016/j.neuropharm.2013.03.014. Epub 2013 Mar 30.

PMID:
23548702
5.

Salvianolic acid B inhibits the TLR4-NFκB-TNFα pathway and attenuates neonatal rat cardiomyocyte injury induced by lipopolysaccharide.

Wang J, Zhang Y, Guo LL, Wu GJ, Liu RH.

Chin J Integr Med. 2011 Oct;17(10):775-9. doi: 10.1007/s11655-011-0877-x. Epub 2011 Nov 19.

PMID:
22101700
6.

Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain.

Rummel C, Sachot C, Poole S, Luheshi GN.

Am J Physiol Regul Integr Comp Physiol. 2006 Nov;291(5):R1316-26. Epub 2006 Jun 29.

7.

Fever, sickness behavior, and expression of inflammatory genes in the hypothalamus after systemic and localized subcutaneous stimulation of rats with the Toll-like receptor 7 agonist imiquimod.

Damm J, Wiegand F, Harden LM, Gerstberger R, Rummel C, Roth J.

Neuroscience. 2012 Jan 10;201:166-83. doi: 10.1016/j.neuroscience.2011.11.013. Epub 2011 Nov 12.

PMID:
22116053
8.

Site-specific modulation of LPS-induced fever and interleukin-1 beta expression in rats by interleukin-10.

Ledeboer A, Binnekade R, Brevé JJ, Bol JG, Tilders FJ, Van Dam AM.

Am J Physiol Regul Integr Comp Physiol. 2002 Jun;282(6):R1762-72.

9.

Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits.

Huang WT, Niu KC, Chang CK, Lin MT, Chang CP.

Eur J Pharmacol. 2008 Sep 28;593(1-3):105-11. doi: 10.1016/j.ejphar.2008.07.017. Epub 2008 Jul 15.

PMID:
18664365
10.

Fever suppression in near-term pregnant rats is dissociated from LPS-activated signaling pathways.

Mouihate A, Ellis S, Harré EM, Pittman QJ.

Am J Physiol Regul Integr Comp Physiol. 2005 Nov;289(5):R1265-72. Epub 2005 Jul 21.

12.

Blocking NF-kappaB activation may be an effective strategy in the fever therapy.

Lee JJ, Huang WT, Shao DZ, Liao JF, Lin MT.

Jpn J Physiol. 2003 Oct;53(5):367-75.

PMID:
14975183
13.

Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain.

Fuchs F, Damm J, Gerstberger R, Roth J, Rummel C.

J Neuroinflammation. 2013 Nov 26;10:140. doi: 10.1186/1742-2094-10-140.

14.

Sesquiterpene lactones are potent inhibitors of interleukin 8 gene expression in cultured human respiratory epithelium.

Mazor RL, Menendez IY, Ryan MA, Fiedler MA, Wong HR.

Cytokine. 2000 Mar;12(3):239-45.

PMID:
10704251
15.

Sesquiterpene lactone parthenolide blocks lipopolysaccharide-induced osteolysis through the suppression of NF-kappaB activity.

Yip KH, Zheng MH, Feng HT, Steer JH, Joyce DA, Xu J.

J Bone Miner Res. 2004 Nov;19(11):1905-16. Epub 2004 Sep 27.

17.

Nuclear translocation of the transcription factor STAT3 in the guinea pig brain during systemic or localized inflammation.

Rummel C, Hübschle T, Gerstberger R, Roth J.

J Physiol. 2004 Jun 1;557(Pt 2):671-87. Epub 2004 Feb 13.

18.

Insulin regulates cytokines and intercellular adhesion molecule-1 gene expression through nuclear factor-kappaB activation in LPS-induced acute lung injury in rats.

Martins JO, Zanoni FL, Martins DO, Coimbra R, Krieger JE, Jancar S, Sannomiya P.

Shock. 2009 Apr;31(4):404-9. doi: 10.1097/SHK.0b013e318186275e.

PMID:
18791499
19.

Macrophage-activating lipopeptide-2 (MALP-2) induces a localized inflammatory response in rats resulting in activation of brain sites implicated in fever.

Knorr C, Hübschle T, Murgott J, Mühlradt P, Gerstberger R, Roth J.

Brain Res. 2008 Apr 18;1205:36-46. doi: 10.1016/j.brainres.2008.02.021. Epub 2008 Feb 21.

PMID:
18353287
20.

Fever induction pathways: evidence from responses to systemic or local cytokine formation.

Roth J, De Souza GE.

Braz J Med Biol Res. 2001 Mar;34(3):301-14. Review.

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