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Results: 1 to 20 of 200

1.

ATM controls meiotic double-strand-break formation.

Lange J, Pan J, Cole F, Thelen MP, Jasin M, Keeney S.

Nature. 2011 Oct 16;479(7372):237-40. doi: 10.1038/nature10508.

PMID:
22002603
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR).

Gray S, Allison RM, Garcia V, Goldman AS, Neale MJ.

Open Biol. 2013 Jul 31;3(7):130019. doi: 10.1098/rsob.130019.

PMID:
23902647
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes.

Bellani MA, Romanienko PJ, Cairatti DA, Camerini-Otero RD.

J Cell Sci. 2005 Aug 1;118(Pt 15):3233-45. Epub 2005 Jul 5.

PMID:
15998665
[PubMed - indexed for MEDLINE]
Free Article
4.

ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes.

Barchi M, Roig I, Di Giacomo M, de Rooij DG, Keeney S, Jasin M.

PLoS Genet. 2008 May 23;4(5):e1000076. doi: 10.1371/journal.pgen.1000076.

PMID:
18497861
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages.

Liebe B, Petukhova G, Barchi M, Bellani M, Braselmann H, Nakano T, Pandita TK, Jasin M, Fornace A, Meistrich ML, Baarends WM, Schimenti J, de Lange T, Keeney S, Camerini-Otero RD, Scherthan H.

Exp Cell Res. 2006 Nov 15;312(19):3768-81. Epub 2006 Aug 2.

PMID:
17010969
[PubMed - indexed for MEDLINE]
6.

Endonucleolytic processing of covalent protein-linked DNA double-strand breaks.

Neale MJ, Pan J, Keeney S.

Nature. 2005 Aug 18;436(7053):1053-7.

PMID:
16107854
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair.

Joyce EF, Pedersen M, Tiong S, White-Brown SK, Paul A, Campbell SD, McKim KS.

J Cell Biol. 2011 Oct 31;195(3):359-67. doi: 10.1083/jcb.201104121. Epub 2011 Oct 24.

PMID:
22024169
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Budding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-regulating Rec114, an essential component of the DSB-machinery.

Carballo JA, Panizza S, Serrentino ME, Johnson AL, Geymonat M, Borde V, Klein F, Cha RS.

PLoS Genet. 2013 Jun;9(6):e1003545. doi: 10.1371/journal.pgen.1003545. Epub 2013 Jun 27.

PMID:
23825959
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.

Goodarzi AA, Jeggo P, Lobrich M.

DNA Repair (Amst). 2010 Dec 10;9(12):1273-82. doi: 10.1016/j.dnarep.2010.09.013. Epub 2010 Oct 30. Review.

PMID:
21036673
[PubMed - indexed for MEDLINE]
10.

Programmed phosphorylation of histone H2AX precedes a phase of DNA double-strand break-independent synapsis in mouse meiosis.

Blanco-Rodríguez J.

Reproduction. 2012 Dec;144(6):699-712. doi: 10.1530/REP-12-0326. Epub 2012 Oct 3.

PMID:
23035256
[PubMed - indexed for MEDLINE]
Free Article
11.

The mammalian mid-pachytene checkpoint: meiotic arrest in spermatocytes with a mutation in Atm alone or in combination with a Trp53 (p53) or Cdkn1a (p21/cip1) mutation.

Ashley T, Westphal C, Plug-de Maggio A, de Rooij DG.

Cytogenet Genome Res. 2004;107(3-4):256-62.

PMID:
15467370
[PubMed - indexed for MEDLINE]
12.

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.

Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW.

Nature. 2011 Jan 13;469(7329):250-4. doi: 10.1038/nature09604. Epub 2010 Dec 15.

PMID:
21160472
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The impact of heterochromatin on DSB repair.

Goodarzi AA, Noon AT, Jeggo PA.

Biochem Soc Trans. 2009 Jun;37(Pt 3):569-76. doi: 10.1042/BST0370569.

PMID:
19442252
[PubMed - indexed for MEDLINE]
14.

Direct and indirect control of the initiation of meiotic recombination by DNA damage checkpoint mechanisms in budding yeast.

Argunhan B, Farmer S, Leung WK, Terentyev Y, Humphryes N, Tsubouchi T, Toyoizumi H, Tsubouchi H.

PLoS One. 2013 Jun 10;8(6):e65875. doi: 10.1371/journal.pone.0065875. Print 2013.

PMID:
23762445
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mammalian meiosis involves DNA double-strand breaks with 3' overhangs.

Zenvirth D, Richler C, Bardhan A, Baudat F, Barzilai A, Wahrman J, Simchen G.

Chromosoma. 2003 Mar;111(6):369-76. Epub 2003 Jan 25.

PMID:
12644952
[PubMed - indexed for MEDLINE]
16.

Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants.

Di Giacomo M, Barchi M, Baudat F, Edelmann W, Keeney S, Jasin M.

Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):737-42. Epub 2005 Jan 7.

PMID:
15640358
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.

Tomimatsu N, Tahimic CG, Otsuki A, Burma S, Fukuhara A, Sato K, Shiota G, Oshimura M, Chen DJ, Kurimasa A.

J Biol Chem. 2007 Apr 6;282(14):10138-45. Epub 2007 Feb 1.

PMID:
17272272
[PubMed - indexed for MEDLINE]
Free Article
18.

Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Xue L, Yu D, Furusawa Y, Okayasu R, Tong J, Cao J, Fan S.

Mutat Res. 2009 Nov 2;670(1-2):15-23. doi: 10.1016/j.mrfmmm.2009.06.016. Epub 2009 Jul 5.

PMID:
19583974
[PubMed - indexed for MEDLINE]
19.

Both ATM and ATR promote the efficient and accurate processing of programmed meiotic double-strand breaks.

Culligan KM, Britt AB.

Plant J. 2008 Aug;55(4):629-38. doi: 10.1111/j.1365-313X.2008.03530.x. Epub 2008 Apr 24.

PMID:
18435824
[PubMed - indexed for MEDLINE]
20.

Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells.

Rass E, Chandramouly G, Zha S, Alt FW, Xie A.

J Biol Chem. 2013 Mar 8;288(10):7086-95. doi: 10.1074/jbc.M112.445825. Epub 2013 Jan 26.

PMID:
23355489
[PubMed - indexed for MEDLINE]
Free PMC Article

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