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Results: 1 to 20 of 102

1.

Identification of the Schistosoma mansoni molecular target for the antimalarial drug artemether.

Lepore R, Simeoni S, Raimondo D, Caroli A, Tramontano A, Via A.

J Chem Inf Model. 2011 Nov 28;51(11):3005-16. doi: 10.1021/ci2001764. Epub 2011 Oct 28.

PMID:
21995318
[PubMed - indexed for MEDLINE]
2.

Effect of artemether administered alone or in combination with praziquantel to mice infected with Plasmodium berghei or Schistosoma mansoni or both.

Shu-Hua X, Utzinger J, Chollet J, Tanner M.

Int J Parasitol. 2006 Jul;36(8):957-64. Epub 2006 Apr 25.

PMID:
16750833
[PubMed - indexed for MEDLINE]
3.

The binding modes and binding affinities of artemisinin derivatives with Plasmodium falciparum Ca2+-ATPase (PfATP6).

Naik PK, Srivastava M, Bajaj P, Jain S, Dubey A, Ranjan P, Kumar R, Singh H.

J Mol Model. 2011 Feb;17(2):333-57. doi: 10.1007/s00894-010-0726-4. Epub 2010 May 12.

PMID:
20461426
[PubMed - indexed for MEDLINE]
4.

Combined receptor-based and ligand-based approach to delineate the mode of binding of guaianolide-endoperoxides to PfATP6.

Helal MA, Avery MA.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5410-4. doi: 10.1016/j.bmcl.2012.07.053. Epub 2012 Jul 20.

PMID:
22877631
[PubMed - indexed for MEDLINE]
5.

Oral artemether for prevention of Schistosoma mansoni infection: randomised controlled trial.

Utzinger J, N'Goran EK, N'Dri A, Lengeler C, Xiao S, Tanner M.

Lancet. 2000 Apr 15;355(9212):1320-5.

PMID:
10776745
[PubMed - indexed for MEDLINE]
6.

Mechanism of antimalarial action of the synthetic trioxolane RBX11160 (OZ277).

Uhlemann AC, Wittlin S, Matile H, Bustamante LY, Krishna S.

Antimicrob Agents Chemother. 2007 Feb;51(2):667-72. Epub 2006 Dec 4.

PMID:
17145800
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A single amino acid residue can determine the sensitivity of SERCAs to artemisinins.

Uhlemann AC, Cameron A, Eckstein-Ludwig U, Fischbarg J, Iserovich P, Zuniga FA, East M, Lee A, Brady L, Haynes RK, Krishna S.

Nat Struct Mol Biol. 2005 Jul;12(7):628-9. Epub 2005 Jun 5. Erratum in: Nat Struct Mol Biol. 2012 Feb;19(2):264.

PMID:
15937493
[PubMed - indexed for MEDLINE]
8.

Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents.

Lanfranchi DA, Cesar-Rodo E, Bertrand B, Huang HH, Day L, Johann L, Elhabiri M, Becker K, Williams DL, Davioud-Charvet E.

Org Biomol Chem. 2012 Aug 21;10(31):6375-87. doi: 10.1039/c2ob25812a. Epub 2012 Jul 10.

PMID:
22777178
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Antimalarial screening via large-scale purification of Plasmodium falciparum Ca2+-ATPase 6 and in vitro studies.

David-Bosne S, Florent I, Lund-Winther AM, Hansen JB, Buch-Pedersen M, Machillot P, le Maire M, Jaxel C.

FEBS J. 2013 Nov;280(21):5419-29. doi: 10.1111/febs.12244. Epub 2013 Apr 8.

PMID:
23497141
[PubMed - indexed for MEDLINE]
10.

Effect of combined treatment with praziquantel and artemether on Schistosoma japonicum and Schistosoma mansoni in experimentally infected animals.

Utzinger J, Chollet J, You J, Mei J, Tanner M, Xiao S.

Acta Trop. 2001 Sep 1;80(1):9-18.

PMID:
11495639
[PubMed - indexed for MEDLINE]
11.

In vitro and in vivo studies of the effect of artemether on Schistosoma mansoni.

Xiao SH, Catto BA.

Antimicrob Agents Chemother. 1989 Sep;33(9):1557-62.

PMID:
2510595
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Malaria: to kill a parasite.

Ridley RG.

Nature. 2003 Aug 21;424(6951):887-9. No abstract available.

PMID:
12931167
[PubMed - indexed for MEDLINE]
13.

Docking studies of structurally diverse antimalarial drugs targeting PfATP6: no correlation between in silico binding affinity and in vitro antimalarial activity.

Garah FB, Stigliani JL, Coslédan F, Meunier B, Robert A.

ChemMedChem. 2009 Sep;4(9):1469-79. doi: 10.1002/cmdc.200900200.

PMID:
19645001
[PubMed - indexed for MEDLINE]
14.

Effect of artemether on Schistosoma mansoni: dose-efficacy relationship, and changes in worm morphology and histopathology.

Xiao SH, Guo J, Chollet J, Wu JT, Tanner M, Utzinger J.

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2004 Jun;22(3):148-53.

PMID:
15597709
[PubMed - indexed for MEDLINE]
15.

Antimalarial activity of artemisinins: identification of a novel target?

Mercereau-Puijalon O, Fandeur T.

Lancet. 2003 Dec 20;362(9401):2035-6. No abstract available.

PMID:
14697798
[PubMed - indexed for MEDLINE]
16.

Artemisinins target the SERCA of Plasmodium falciparum.

Eckstein-Ludwig U, Webb RJ, Van Goethem ID, East JM, Lee AG, Kimura M, O'Neill PM, Bray PG, Ward SA, Krishna S.

Nature. 2003 Aug 21;424(6951):957-61.

PMID:
12931192
[PubMed - indexed for MEDLINE]
17.

[Antischistosomal activity of artemether in experimental Schistosomiasis mansoni].

Lescano SZ, Chieffi PP, Canhassi RR, Boulos M, Amato Neto V.

Rev Saude Publica. 2004 Feb;38(1):71-5. Epub 2004 Jan 30. Portuguese.

PMID:
14963544
[PubMed - indexed for MEDLINE]
Free Article
18.

Tegumental changes in adult Schistosoma mansoni harbored in mice treated with artemether.

Xiao S, Shen B, Chollet J, Utzinger J, Tanner M.

J Parasitol. 2000 Oct;86(5):1125-32.

PMID:
11128492
[PubMed - indexed for MEDLINE]
19.

Diversity of the sarco/endoplasmic reticulum Ca(2+)-ATPase orthologue of Plasmodium falciparum (PfATP6).

Dahlström S, Veiga MI, Ferreira P, Mårtensson A, Kaneko A, Andersson B, Björkman A, Gil JP.

Infect Genet Evol. 2008 May;8(3):340-5. doi: 10.1016/j.meegid.2008.02.002. Epub 2008 Feb 15.

PMID:
18359278
[PubMed - indexed for MEDLINE]

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