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Items: 1 to 20 of 73

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2.

IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism.

Löb S, Königsrainer A, Zieker D, Brücher BL, Rammensee HG, Opelz G, Terness P.

Cancer Immunol Immunother. 2009 Jan;58(1):153-7. doi: 10.1007/s00262-008-0513-6. Epub 2008 Apr 17.

PMID:
18418598
3.

Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials.

Yuasa HJ, Ball HJ, Ho YF, Austin CJ, Whittington CM, Belov K, Maghzal GJ, Jermiin LS, Hunt NH.

Comp Biochem Physiol B Biochem Mol Biol. 2009 Jun;153(2):137-144. Epub 2009 Feb 7.

PMID:
19416693
4.

Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials.

Yuasa HJ, Ball HJ, Ho YF, Austin CJ, Whittington CM, Belov K, Maghzal GJ, Jermiin LS, Hunt NH.

Comp Biochem Physiol B Biochem Mol Biol. 2009 Jun;153(2):137-44.

PMID:
19402226
5.

IDO1 and IDO2 gene expression analysis by quantitative polymerase chain reaction.

Maiwald S, Wehner R, Schmitz M, Bornhäuser M, Loeb S, Wassmuth R.

Tissue Antigens. 2011 Feb;77(2):136-42. doi: 10.1111/j.1399-0039.2010.01585.x. Epub 2010 Nov 24.

PMID:
21092022
6.

Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis.

Fukunaga M, Yamamoto Y, Kawasoe M, Arioka Y, Murakami Y, Hoshi M, Saito K.

J Histochem Cytochem. 2012 Nov;60(11):854-60. doi: 10.1369/0022155412458926. Epub 2012 Aug 15.

7.

Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2.

Austin CJ, Mailu BM, Maghzal GJ, Sanchez-Perez A, Rahlfs S, Zocher K, Yuasa HJ, Arthur JW, Becker K, Stocker R, Hunt NH, Ball HJ.

Amino Acids. 2010 Jul;39(2):565-78. doi: 10.1007/s00726-010-0475-9. Epub 2010 Feb 7.

PMID:
20140689
8.

Novel 1-alkyl-tryptophan derivatives downregulate IDO1 and IDO2 mRNA expression induced by interferon-gamma in dendritic cells.

Sun T, Chen XH, Tang ZD, Cai J, Wang XY, Wang SC, Li ZL.

Mol Cell Biochem. 2010 Sep;342(1-2):29-34. doi: 10.1007/s11010-010-0465-y. Epub 2010 Apr 28.

PMID:
20424892
9.

Low efficiency IDO2 enzymes are conserved in lower vertebrates, whereas higher efficiency IDO1 enzymes are dispensable.

Yuasa HJ, Mizuno K, Ball HJ.

FEBS J. 2015 Jul;282(14):2735-45. doi: 10.1111/febs.13316. Epub 2015 May 20.

PMID:
25950090
10.

Indoleamine 2,3-dioxygenase activity in nonagenarians is markedly increased and predicts mortality.

Pertovaara M, Raitala A, Lehtimäki T, Karhunen PJ, Oja SS, Jylhä M, Hervonen A, Hurme M.

Mech Ageing Dev. 2006 May;127(5):497-9. Epub 2006 Feb 28.

PMID:
16513157
11.

IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis.

Merlo LM, Pigott E, DuHadaway JB, Grabler S, Metz R, Prendergast GC, Mandik-Nayak L.

J Immunol. 2014 Mar 1;192(5):2082-90. doi: 10.4049/jimmunol.1303012. Epub 2014 Jan 31.

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Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells.

Lob S, Konigsrainer A, Schafer R, Rammensee HG, Opelz G, Terness P.

Blood. 2008 Feb 15;111(4):2152-4. Epub 2007 Nov 28.

14.

Enhanced indoleamine 2,3-dioxygenase activity in patients with severe sepsis and septic shock.

Tattevin P, Monnier D, Tribut O, Dulong J, Bescher N, Mourcin F, Uhel F, Le Tulzo Y, Tarte K.

J Infect Dis. 2010 Mar 15;201(6):956-66. doi: 10.1086/650996.

15.

Molecular evolution and characterization of fungal indoleamine 2,3-dioxygenases.

Yuasa HJ, Ball HJ.

J Mol Evol. 2011 Feb;72(2):160-8. doi: 10.1007/s00239-010-9412-5. Epub 2010 Dec 18.

PMID:
21170645
16.

Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors.

Koblish HK, Hansbury MJ, Bowman KJ, Yang G, Neilan CL, Haley PJ, Burn TC, Waeltz P, Sparks RB, Yue EW, Combs AP, Scherle PA, Vaddi K, Fridman JS.

Mol Cancer Ther. 2010 Feb;9(2):489-98. doi: 10.1158/1535-7163.MCT-09-0628. Epub 2010 Feb 2.

17.

Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors.

Meininger D, Zalameda L, Liu Y, Stepan LP, Borges L, McCarter JD, Sutherland CL.

Biochim Biophys Acta. 2011 Dec;1814(12):1947-54. doi: 10.1016/j.bbapap.2011.07.023. Epub 2011 Jul 31.

PMID:
21835273
18.

Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway.

Ball HJ, Yuasa HJ, Austin CJ, Weiser S, Hunt NH.

Int J Biochem Cell Biol. 2009 Mar;41(3):467-71. doi: 10.1016/j.biocel.2008.01.005. Epub 2008 Jan 11. Review.

PMID:
18282734
19.

Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.

Schefold JC, Zeden JP, Fotopoulou C, von Haehling S, Pschowski R, Hasper D, Volk HD, Schuett C, Reinke P.

Nephrol Dial Transplant. 2009 Jun;24(6):1901-8. doi: 10.1093/ndt/gfn739. Epub 2009 Jan 20.

20.
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