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Results: 1 to 20 of 93

1.

N-acetylgalactosamine kinase: a naturally promiscuous small molecule kinase.

Kristiansson H, Timson DJ.

Appl Biochem Biotechnol. 2012 Jan;166(1):57-63. doi: 10.1007/s12010-011-9403-z. Epub 2011 Oct 8.

PMID:
21984386
[PubMed - indexed for MEDLINE]
2.

The molecular architecture of human N-acetylgalactosamine kinase.

Thoden JB, Holden HM.

J Biol Chem. 2005 Sep 23;280(38):32784-91. Epub 2005 Jul 8.

PMID:
16006554
[PubMed - indexed for MEDLINE]
Free Article
3.

Mechanistic studies on human N-acetylgalactosamine kinase.

Agnew A, Timson D.

J Enzyme Inhib Med Chem. 2010 Jun;25(3):370-6. doi: 10.3109/14756360903179492.

PMID:
19874134
[PubMed - indexed for MEDLINE]
4.

Sugar recognition by human galactokinase.

Timson DJ, Reece RJ.

BMC Biochem. 2003 Nov 4;4:16.

PMID:
14596685
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Increased promiscuity of human galactokinase following alteration of a single amino acid residue distant from the active site.

Kristiansson H, Timson DJ.

Chembiochem. 2011 Sep 5;12(13):2081-7. doi: 10.1002/cbic.201100308. Epub 2011 Jul 11.

PMID:
21748839
[PubMed - indexed for MEDLINE]
6.

Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.

Zhou T, Daugherty M, Grishin NV, Osterman AL, Zhang H.

Structure. 2000 Dec 15;8(12):1247-57.

PMID:
11188689
[PubMed - indexed for MEDLINE]
7.

Role of Arg228 in the phosphorylation of galactokinase: the mechanism of GHMP kinases by quantum mechanics/molecular mechanics studies.

Huang M, Li X, Zou JW, Timson DJ.

Biochemistry. 2013 Jul 16;52(28):4858-68. doi: 10.1021/bi400228e. Epub 2013 Jul 1.

PMID:
23786354
[PubMed - indexed for MEDLINE]
8.

Identification of the GalNAc kinase amino acid sequence.

Pastuszak I, O'Donnell J, Elbein AD.

J Biol Chem. 1996 Sep 27;271(39):23653-6.

PMID:
8798585
[PubMed - indexed for MEDLINE]
Free Article
9.

The role of the active site residues in human galactokinase: implications for the mechanisms of GHMP kinases.

Megarity CF, Huang M, Warnock C, Timson DJ.

Bioorg Chem. 2011 Jun;39(3):120-6. doi: 10.1016/j.bioorg.2011.03.001. Epub 2011 Mar 21.

PMID:
21474160
[PubMed - indexed for MEDLINE]
10.

Kidney N-acetylgalactosamine (GalNAc)-1-phosphate kinase, a new pathway of GalNAc activation.

Pastuszak I, Drake R, Elbein AD.

J Biol Chem. 1996 Aug 23;271(34):20776-82.

PMID:
8702831
[PubMed - indexed for MEDLINE]
Free Article
11.

Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily.

Yang D, Shipman LW, Roessner CA, Scott AI, Sacchettini JC.

J Biol Chem. 2002 Mar 15;277(11):9462-7. Epub 2001 Dec 19.

PMID:
11751891
[PubMed - indexed for MEDLINE]
Free Article
12.

Structures of human N-Acetylglucosamine kinase in two complexes with N-Acetylglucosamine and with ADP/glucose: insights into substrate specificity and regulation.

Weihofen WA, Berger M, Chen H, Saenger W, Hinderlich S.

J Mol Biol. 2006 Dec 1;364(3):388-99. Epub 2006 Sep 3.

PMID:
17010375
[PubMed - indexed for MEDLINE]
13.

The nucleotide-binding site of human sphingosine kinase 1.

Pitson SM, Moretti PA, Zebol JR, Zareie R, Derian CK, Darrow AL, Qi J, D'Andrea RJ, Bagley CJ, Vadas MA, Wattenberg BW.

J Biol Chem. 2002 Dec 20;277(51):49545-53. Epub 2002 Oct 18.

PMID:
12393916
[PubMed - indexed for MEDLINE]
Free Article
14.

Creation of the first anomeric D/L-sugar kinase by means of directed evolution.

Hoffmeister D, Yang J, Liu L, Thorson JS.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13184-9.

PMID:
14612558
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase.

Hartley A, Glynn SE, Barynin V, Baker PJ, Sedelnikova SE, Verhees C, de Geus D, van der Oost J, Timson DJ, Reece RJ, Rice DW.

J Mol Biol. 2004 Mar 19;337(2):387-98.

PMID:
15003454
[PubMed - indexed for MEDLINE]
16.

Crystal structures of N-acetylmannosamine kinase provide insights into enzyme activity and inhibition.

Martinez J, Nguyen LD, Hinderlich S, Zimmer R, Tauberger E, Reutter W, Saenger W, Fan H, Moniot S.

J Biol Chem. 2012 Apr 20;287(17):13656-65. doi: 10.1074/jbc.M111.318170. Epub 2012 Feb 16.

PMID:
22343627
[PubMed - indexed for MEDLINE]
Free PMC Article
17.
18.

Biosynthesis of N-acetylneuraminic acid in cells lacking UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.

Hinderlich S, Berger M, Keppler OT, Pawlita M, Reutter W.

Biol Chem. 2001 Feb;382(2):291-7.

PMID:
11308027
[PubMed - indexed for MEDLINE]
19.

Molecular functions of conserved aspects of the GHMP kinase family.

Andreassi JL 2nd, Leyh TS.

Biochemistry. 2004 Nov 23;43(46):14594-601.

PMID:
15544330
[PubMed - indexed for MEDLINE]
20.

Wide sugar substrate specificity of galactokinase from Streptococcus pneumoniae TIGR4.

Chen M, Chen LL, Zou Y, Xue M, Liang M, Jin L, Guan WY, Shen J, Wang W, Wang L, Liu J, Wang PG.

Carbohydr Res. 2011 Nov 8;346(15):2421-5. doi: 10.1016/j.carres.2011.08.014. Epub 2011 Aug 22.

PMID:
21903203
[PubMed - indexed for MEDLINE]

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