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21972213,21126163,21993235,18594515,21548079,17724450,18951379,20689077,19816951,23264997,25181424,25437870,23132827,22420535,20965232,20504151,20336525,22868173,20513630,21074831,19736564,17971807,18425776,21478453,25422984,17314316,19409607,19415770,18185576,26604326,19030024,19060217,21252149,18045526,17632550,18656469,24892478,19697349,21956995,18157115,25418733,20014278,20575428,19922768,19618464,20221419,28636277,23326334,18983970,23278808,30013107,25194736,22079579,19605512,26947975,23280629,31389301,19337237,23333380,23747203,23050522,22578162,23613252,26877091,21933286,19178078,20698766,23524261,25889591,24123501,25513856,16904174,24501429,26785054,26657769,23421367,21975513,26776886,22976998,23264996,30277824,20380514,22697119,23782837,19403798,22293932,23828673,23731893,27514449,23276226,26992828,19041774,21944493,21958637,21131959,23089465,21085182,19696409,20096661,23748715,19890879,21103067,18845712,26740582,19501410,19645026,27600094,22653585,25441442,19637940,18957414,17515932,20936906,25619399,20945330,19944068,18818365,19554373,23314866,20510497,31393170,18414447,27247273,24945968,23877993,29531310,26453549,22589234,28230233,22014056,26882313,21852325,24618595,24560741,18388306,23132243,26053519,21254851,22508949,27012206,19522013,21391916,25542179,20025521,22659081,23097321,33226621,22897623,25185564,19139101,19738434,19839055,26982160,24183713,20303530,21909390,25825768,19036726,16894532,22205615,23295861,28436127,22217670,22031517,28253866,22327294,20146301,20879854,23213213,27790870,23527287,22743827,22204592,22761414,31298467,36927767,23780512,16460563,23283489,21962512,26505250,19696013,32991228,20384793,23871606,26756580,21609209,20621050,22909387,28776863,24879426,22528804,25529151,19136965,28731785,27459582,21982273,29685182,24153105,23329853,24929238,28533192,28632762,21380643,27460218,27625395,22745796,22989381,21048080,22686476,23279472,17827181,26975336,23846396,24036272,20621043,24504341,25342174,26411691,29180509,25385323,23788624,20203661,23159369,23571855,22215994,19345177,23065456,21844894,20937839,18806776,19542351,19383391,24113379,22127235,28545230,19797193,24630793,24464032,24325731,19151700,27048287,23386720,18024420,21089074,15582778,19008347,18946985,20410807,28378634,24360205,19564890,24038603,19631602,21457962,31576792,19492421,23934214,22479535,20457152,21547061,23257394,23088445,21804543,25509123,23939908,22787153,22217199,18724799,25495180,18154436,26991423,18802003,23225459,31353083,18330925,18824471,24338401,24256201,20920475,23244832,17554336,22339199,20417198,26938105,21988203,19541600,23625189,21681859,24623076,24742229,28111071,18571647,26203860,22914767,28247195,23178592,20646110,25501223,27245508,28509990,24170349,20850729,26206603,22355722,19376775,22034826,27996082,24018616,28103575,22531103,20574542,22539273,22576801,18347094,19591226,30196805,26733157,34037424,22639061,19096035,24553769,28091581,33451972,26447186,24679907,21732481,19216758,24602917,30770896,21244367,25736622,18682236,28557624,23057961,22539002,23762465,25145414,22669820,23708003,18996616,21276239,19809223,27495230,24511468,22258410,23376973,24884521,21678036,21241188,26416515,21261607,30735078,22339667,31444221,24389873,20512590,17196087,21729377,29135280,19199344,19815608,19848289,22357549,20353723,23719110,26661329,25377420,23301671,24889158,17636440,25940188,31227724,20974014,20668695,25851587,35788719,21483788,26836033,25223935,28241084,27253625,20212135,28665977,23271363,21419292,23762260,19701907,24236059,23311131,25077841,23256541,20962633,34502264,34879895,26654770,23863483,27442780,24244203,22444263,28004977,20232320,24930113,25628230,23554223,25421381,20736286,32798382,21617704,24563300,23246144,34839950,20089153,23119091,27732616,27406998,22865647,26896855,22515122,22992956,18371417,25209725,22334693,26298849,27622636,23426569,26369430,25173648,26076706,24051058,24125057,23172713,24462001,27015307,19049416,24056933,23088399,30325654,25633044,15749924,23649762,31983707,25775469,19669668,21480394,27225481,34250657,23969249,21419743,24020699,30277598,24836291,20936903,29943354,24167316,36001968,23441574,33810223,20132009,12381664,18983969,31218974,34452543,29546598,17009897,23706735,22948941,30447341,19906868,24037901,23251622,25660622,12620990,31182178,19421239,22977234,10993824,21706347,22871540,20133594,16978048,23468991,16513118,23752184,19845688,18181941,23272044,34440750,35883229,17671453,23287475,24076032,25360692,23544704,26660476,22562197,21209933,33180827,23303676,22311040,25312433,18942890,31161749,19763270,21543769,16791199,25429426,26884828,19622035,20580711,31429169,22038863,33668852,22381475,25476026,17442571,27015308,25556182,28805244,21705331,24023739,32518050,25267505,16988381,28711491,23613880,30055542,23307247,21885013,26299657,28446706,35733702,18578590,35432738,30981668,22406932,19537945,20715180,21547058,26518291,27472467,32578338,28264735,23272250,37041343,24957798,19937273,19341623,19845468,23979878,19447925,25685732,29974990,26086202,25895477,28684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674 results

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Overexpression Nanog activates pluripotent genes in porcine fetal fibroblasts and nuclear transfer embryos.

Zhang L, Luo YB, Bou G, Kong QR, Huan YJ, Zhu J, Wang JY, Li H, Wang F, Shi YQ, Wei YC, Liu ZH. Zhang L, et al. Anat Rec (Hoboken). 2011 Nov;294(11):1809-17. doi: 10.1002/ar.21457. Epub 2011 Oct 3. Anat Rec (Hoboken). 2011. PMID: 21972213 Free article.

Oct4-enhanced green fluorescent protein transgenic pigs: a new large animal model for reprogramming studies.

Nowak-Imialek M, Kues WA, Petersen B, Lucas-Hahn A, Herrmann D, Haridoss S, Oropeza M, Lemme E, Schöler HR, Carnwath JW, Niemann H. Nowak-Imialek M, et al. Stem Cells Dev. 2011 Sep;20(9):1563-75. doi: 10.1089/scd.2010.0399. Epub 2011 Jan 12. Stem Cells Dev. 2011. PMID: 21126163

Activation of pluripotency-associated genes in mouse embryonic fibroblasts by non-viral transfection with in vitro-derived mRNAs encoding Oct4, Sox2, Klf4 and cMyc.

Tavernier G, Wolfrum K, Demeester J, De Smedt SC, Adjaye J, Rejman J. Tavernier G, et al. Biomaterials. 2012 Jan;33(2):412-7. doi: 10.1016/j.biomaterials.2011.09.062. Epub 2011 Oct 10. Biomaterials. 2012. PMID: 21993235

Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors.

Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Araúzo-Bravo MJ, Ruau D, Han DW, Zenke M, Schöler HR. Kim JB, et al. Nature. 2008 Jul 31;454(7204):646-50. doi: 10.1038/nature07061. Epub 2008 Jun 29. Nature. 2008. PMID: 18594515

Optimal reprogramming factor stoichiometry increases colony numbers and affects molecular characteristics of murine induced pluripotent stem cells.

Tiemann U, Sgodda M, Warlich E, Ballmaier M, Schöler HR, Schambach A, Cantz T. Tiemann U, et al. Cytometry A. 2011 Jun;79(6):426-35. doi: 10.1002/cyto.a.21072. Epub 2011 May 4. Cytometry A. 2011. PMID: 21548079 Free article.

Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells.

Meissner A, Wernig M, Jaenisch R. Meissner A, et al. Nat Biotechnol. 2007 Oct;25(10):1177-81. doi: 10.1038/nbt1335. Epub 2007 Aug 27. Nat Biotechnol. 2007. PMID: 17724450

Gene expression and development of early pig embryos produced by serial nuclear transfer.

Xing X, Magnani L, Lee K, Wang C, Cabot RA, Machaty Z. Xing X, et al. Mol Reprod Dev. 2009 Jun;76(6):555-63. doi: 10.1002/mrd.20974. Mol Reprod Dev. 2009. PMID: 18951379

Endogenous KLF4 expression in human fetal endothelial cells allows for reprogramming to pluripotency with just OCT3/4 and SOX2--brief report.

Ho PJ, Yen ML, Lin JD, Chen LS, Hu HI, Yeh CK, Peng CY, Lin CY, Yet SF, Yen BL. Ho PJ, et al. Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):1905-7. doi: 10.1161/ATVBAHA.110.206540. Epub 2010 Aug 5. Arterioscler Thromb Vasc Biol. 2010. PMID: 20689077

Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming.

Wei Z, Yang Y, Zhang P, Andrianakos R, Hasegawa K, Lyu J, Chen X, Bai G, Liu C, Pera M, Lu W. Wei Z, et al. Stem Cells. 2009 Dec;27(12):2969-78. doi: 10.1002/stem.231. Stem Cells. 2009. PMID: 19816951

Generation of clinically relevant "induced pluripotent stem" (iPS) cells.

Heffernan C, Sumer H, Verma PJ. Heffernan C, et al. J Stem Cells. 2011;6(3):109-27. J Stem Cells. 2011. PMID: 23264997 Review.

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