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Results: 1 to 20 of 81

1.

Gadd45β is an inducible coactivator of transcription that facilitates rapid liver growth in mice.

Tian J, Huang H, Hoffman B, Liebermann DA, Ledda-Columbano GM, Columbano A, Locker J.

J Clin Invest. 2011 Nov;121(11):4491-502. doi: 10.1172/JCI38760. Epub 2011 Oct 3.

PMID:
21965327
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Gadd45beta is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia.

Columbano A, Ledda-Columbano GM, Pibiri M, Cossu C, Menegazzi M, Moore DD, Huang W, Tian J, Locker J.

Hepatology. 2005 Nov;42(5):1118-26.

PMID:
16231353
[PubMed - indexed for MEDLINE]
3.

The antiapoptotic factor growth arrest and DNA-damage-inducible 45 beta regulates the nuclear receptor constitutive active/androstane receptor-mediated transcription.

Yamamoto Y, Negishi M.

Drug Metab Dispos. 2008 Jul;36(7):1189-93. doi: 10.1124/dmd.108.020628. Epub 2008 Mar 24.

PMID:
18362160
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Gadd45 in the liver: signal transduction and transcriptional mechanisms.

Tian J, Locker J.

Adv Exp Med Biol. 2013;793:69-80. doi: 10.1007/978-1-4614-8289-5_5. Review.

PMID:
24104474
[PubMed - indexed for MEDLINE]
5.

Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport.

Petrick JS, Klaassen CD.

Drug Metab Dispos. 2007 Oct;35(10):1806-15. Epub 2007 Jul 12.

PMID:
17627975
[PubMed - indexed for MEDLINE]
Free Article
6.

SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism.

Chen T, Chen Q, Xu Y, Zhou Q, Zhu J, Zhang H, Wu Q, Xu J, Yu C.

J Hepatol. 2012 Jan;56(1):210-7. doi: 10.1016/j.jhep.2011.07.015. Epub 2011 Aug 7.

PMID:
21827731
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins.

Baskin-Bey ES, Huang W, Ishimura N, Isomoto H, Bronk SF, Braley K, Craig RW, Moore DD, Gores GJ.

Hepatology. 2006 Jul;44(1):252-62.

PMID:
16799968
[PubMed - indexed for MEDLINE]
8.

Peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP) but not PPAR-interacting protein (PRIP) is required for nuclear translocation of constitutive androstane receptor in mouse liver.

Guo D, Sarkar J, Ahmed MR, Viswakarma N, Jia Y, Yu S, Sambasiva Rao M, Reddy JK.

Biochem Biophys Res Commun. 2006 Aug 25;347(2):485-95. Epub 2006 Jun 30.

PMID:
16828057
[PubMed - indexed for MEDLINE]
9.

Gadd45beta promotes hepatocyte survival during liver regeneration in mice by modulating JNK signaling.

Papa S, Zazzeroni F, Fu YX, Bubici C, Alvarez K, Dean K, Christiansen PA, Anders RA, Franzoso G.

J Clin Invest. 2008 May;118(5):1911-23. doi: 10.1172/JCI33913.

PMID:
18382767
[PubMed - indexed for MEDLINE]
Free PMC Article
10.
11.

Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver.

Chen WD, Fu X, Dong B, Wang YD, Shiah S, Moore DD, Huang W.

Hepatology. 2012 Oct;56(4):1499-509. doi: 10.1002/hep.25766.

PMID:
22488010
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B.

Yamamoto Y, Moore R, Flavell RA, Lu B, Negishi M.

PLoS One. 2010 Apr 12;5(4):e10121. doi: 10.1371/journal.pone.0010121.

PMID:
20404936
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The time point of β-catenin knockout in hepatocytes determines their response to xenobiotic activation of the constitutive androstane receptor.

Ganzenberg K, Singh Y, Braeuning A.

Toxicology. 2013 Jun 7;308:113-21. doi: 10.1016/j.tox.2013.03.019. Epub 2013 Apr 8.

PMID:
23578392
[PubMed - indexed for MEDLINE]
14.

Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers.

Rezen T, Tamasi V, Lövgren-Sandblom A, Björkhem I, Meyer UA, Rozman D.

BMC Genomics. 2009 Aug 19;10:384. doi: 10.1186/1471-2164-10-384.

PMID:
19691840
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.

Roth A, Looser R, Kaufmann M, Meyer UA.

Pharmacogenet Genomics. 2008 Apr;18(4):325-37. doi: 10.1097/FPC.0b013e3282f706e0.

PMID:
18334917
[PubMed - indexed for MEDLINE]
16.

C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia.

Blanco-Bose WE, Murphy MJ, Ehninger A, Offner S, Dubey C, Huang W, Moore DD, Trumpp A.

Hepatology. 2008 Oct;48(4):1302-11. doi: 10.1002/hep.22475.

PMID:
18798339
[PubMed - indexed for MEDLINE]
17.

Sex difference in the proliferative response of mouse hepatocytes to treatment with the CAR ligand, TCPOBOP.

Ledda-Columbano GM, Pibiri M, Concas D, Molotzu F, Simbula G, Cossu C, Columbano A.

Carcinogenesis. 2003 Jun;24(6):1059-65. Epub 2003 Apr 24.

PMID:
12807759
[PubMed - indexed for MEDLINE]
Free Article
18.

The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways.

Cai Y, Konishi T, Han G, Campwala KH, French SW, Wan YJ.

Eur J Pharm Sci. 2002 Feb;15(1):89-96.

PMID:
11803135
[PubMed - indexed for MEDLINE]
19.

The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress.

Maglich JM, Lobe DC, Moore JT.

J Lipid Res. 2009 Mar;50(3):439-45. doi: 10.1194/jlr.M800226-JLR200. Epub 2008 Oct 21.

PMID:
18941143
[PubMed - indexed for MEDLINE]
Free Article
20.

Constitutive androstane receptor activation stimulates faecal bile acid excretion and reverse cholesterol transport in mice.

Sberna AL, Assem M, Gautier T, Grober J, Guiu B, Jeannin A, Pais de Barros JP, Athias A, Lagrost L, Masson D.

J Hepatol. 2011 Jul;55(1):154-61. doi: 10.1016/j.jhep.2010.10.029. Epub 2010 Nov 23.

PMID:
21145854
[PubMed - indexed for MEDLINE]
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