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Results: 1 to 20 of 103

1.

Gamma-secretase inhibitor enhances the cytotoxic effect of bortezomib in multiple myeloma.

Chen F, Pisklakova A, Li M, Baz R, Sullivan DM, Nefedova Y.

Cell Oncol (Dordr). 2011 Dec;34(6):545-51. doi: 10.1007/s13402-011-0060-6. Epub 2011 Oct 1.

PMID:
21965140
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Proteasome inhibition as a novel mechanism of the proapoptotic activity of γ-secretase inhibitor I in cutaneous T-cell lymphoma.

Biskup E, Kamstrup MR, Manfé V, Gniadecki R.

Br J Dermatol. 2013 Mar;168(3):504-12. doi: 10.1111/bjd.12071.

PMID:
23445313
[PubMed - indexed for MEDLINE]
3.
4.

Bortezomib resistance in a myeloma cell line is associated to PSMβ5 overexpression and polyploidy.

Balsas P, Galán-Malo P, Marzo I, Naval J.

Leuk Res. 2012 Feb;36(2):212-8. doi: 10.1016/j.leukres.2011.09.011. Epub 2011 Oct 5.

PMID:
21978467
[PubMed - indexed for MEDLINE]
5.

Inhibition of interleukin-6 signaling with CNTO 328 enhances the activity of bortezomib in preclinical models of multiple myeloma.

Voorhees PM, Chen Q, Kuhn DJ, Small GW, Hunsucker SA, Strader JS, Corringham RE, Zaki MH, Nemeth JA, Orlowski RZ.

Clin Cancer Res. 2007 Nov 1;13(21):6469-78.

PMID:
17975159
[PubMed - indexed for MEDLINE]
Free Article
6.

Dll1/Notch activation contributes to bortezomib resistance by upregulating CYP1A1 in multiple myeloma.

Xu D, Hu J, De Bruyne E, Menu E, Schots R, Vanderkerken K, Van Valckenborgh E.

Biochem Biophys Res Commun. 2012 Nov 30;428(4):518-24. doi: 10.1016/j.bbrc.2012.10.071. Epub 2012 Oct 27.

PMID:
23111325
[PubMed - indexed for MEDLINE]
7.

Effect of noncompetitive proteasome inhibition on bortezomib resistance.

Li X, Wood TE, Sprangers R, Jansen G, Franke NE, Mao X, Wang X, Zhang Y, Verbrugge SE, Adomat H, Li ZH, Trudel S, Chen C, Religa TL, Jamal N, Messner H, Cloos J, Rose DR, Navon A, Guns E, Batey RA, Kay LE, Schimmer AD.

J Natl Cancer Inst. 2010 Jul 21;102(14):1069-82. doi: 10.1093/jnci/djq198. Epub 2010 May 26.

PMID:
20505154
[PubMed - indexed for MEDLINE]
Free Article
8.

Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy.

Nefedova Y, Sullivan DM, Bolick SC, Dalton WS, Gabrilovich DI.

Blood. 2008 Feb 15;111(4):2220-9. Epub 2007 Nov 26.

PMID:
18039953
[PubMed - indexed for MEDLINE]
Free Article
9.

The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro.

Poulaki V, Mitsiades CS, Kotoula V, Negri J, McMillin D, Miller JW, Mitsiades N.

Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4706-19.

PMID:
17898295
[PubMed - indexed for MEDLINE]
Free Article
10.

Knockdown of c-Met enhances sensitivity to bortezomib in human multiple myeloma U266 cells via inhibiting Akt/mTOR activity.

Que W, Chen J, Chuang M, Jiang D.

APMIS. 2012 Mar;120(3):195-203. doi: 10.1111/j.1600-0463.2011.02836.x. Epub 2011 Nov 11.

PMID:
22339676
[PubMed - indexed for MEDLINE]
11.
12.

The histone deacetylase inhibitor, PXD101, potentiates bortezomib-induced anti-multiple myeloma effect by induction of oxidative stress and DNA damage.

Feng R, Oton A, Mapara MY, Anderson G, Belani C, Lentzsch S.

Br J Haematol. 2007 Nov;139(3):385-97.

PMID:
17910628
[PubMed - indexed for MEDLINE]
13.

Bortezomib sensitizes primary human esthesioneuroblastoma cells to TRAIL-induced apoptosis.

Koschny R, Holland H, Sykora J, Erdal H, Krupp W, Bauer M, Bockmuehl U, Ahnert P, Meixensberger J, Stremmel W, Walczak H, Ganten TM.

J Neurooncol. 2010 Apr;97(2):171-85. doi: 10.1007/s11060-009-0010-6. Epub 2009 Sep 20.

PMID:
19768634
[PubMed - indexed for MEDLINE]
14.

Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells.

Cascone T, Morelli MP, Morgillo F, Kim WY, Rodolico G, Pepe S, Tortora G, Berrino L, Lee HY, Heymach JV, Ciardiello F.

J Cell Physiol. 2008 Sep;216(3):698-707. doi: 10.1002/jcp.21444. Erratum in: J Cell Physiol. 2008 Oct;217(1):290. Tortora, Giampaolo [added].

PMID:
18381602
[PubMed - indexed for MEDLINE]
15.

Targeting MAGE-C1/CT7 expression increases cell sensitivity to the proteasome inhibitor bortezomib in multiple myeloma cell lines.

de Carvalho F, Costa ET, Camargo AA, Gregorio JC, Masotti C, Andrade VC, Strauss BE, Caballero OL, Atanackovic D, Colleoni GW.

PLoS One. 2011;6(11):e27707. doi: 10.1371/journal.pone.0027707. Epub 2011 Nov 16.

PMID:
22110734
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Caspase-2 functions upstream of mitochondria in endoplasmic reticulum stress-induced apoptosis by bortezomib in human myeloma cells.

Gu H, Chen X, Gao G, Dong H.

Mol Cancer Ther. 2008 Aug;7(8):2298-307. doi: 10.1158/1535-7163.MCT-08-0186.

PMID:
18723477
[PubMed - indexed for MEDLINE]
Free Article
17.

Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.

Gomez-Bougie P, Wuillème-Toumi S, Ménoret E, Trichet V, Robillard N, Philippe M, Bataille R, Amiot M.

Cancer Res. 2007 Jun 1;67(11):5418-24.

PMID:
17545623
[PubMed - indexed for MEDLINE]
Free Article
18.

Cooperation between Apo2L/TRAIL and bortezomib in multiple myeloma apoptosis.

Balsas P, López-Royuela N, Galán-Malo P, Anel A, Marzo I, Naval J.

Biochem Pharmacol. 2009 Mar 1;77(5):804-12. doi: 10.1016/j.bcp.2008.11.024. Epub 2008 Dec 3.

PMID:
19100720
[PubMed - indexed for MEDLINE]
19.

Potentiation of (-)-epigallocatechin-3-gallate-induced apoptosis by bortezomib in multiple myeloma cells.

Wang Q, Li J, Gu J, Huang B, Zhao Y, Zheng D, Ding Y, Zeng L.

Acta Biochim Biophys Sin (Shanghai). 2009 Dec;41(12):1018-26.

PMID:
20011976
[PubMed - indexed for MEDLINE]
Free Article
20.

Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model.

Wang C, Gao D, Guo K, Kang X, Jiang K, Sun C, Li Y, Sun L, Shu H, Jin G, Sun H, Wu W, Liu Y.

BMC Cancer. 2012 May 4;12:166. doi: 10.1186/1471-2407-12-166.

PMID:
22559167
[PubMed - indexed for MEDLINE]
Free PMC Article

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