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Items: 1 to 20 of 83

1.

Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations.

Janssen A, van der Burg M, Szuhai K, Kops GJ, Medema RH.

Science. 2011 Sep 30;333(6051):1895-8. doi: 10.1126/science.1210214.

2.

Chromosomal breaks during mitotic catastrophe trigger γH2AX-ATM-p53-mediated apoptosis.

Imreh G, Norberg HV, Imreh S, Zhivotovsky B.

J Cell Sci. 2011 Sep 1;124(Pt 17):2951-63. doi: 10.1242/jcs.081612.

3.

p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

Song H, Hollstein M, Xu Y.

Nat Cell Biol. 2007 May;9(5):573-80. Epub 2007 Apr 8.

PMID:
17417627
4.

Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability.

Kumareswaran R, Ludkovski O, Meng A, Sykes J, Pintilie M, Bristow RG.

J Cell Sci. 2012 Jan 1;125(Pt 1):189-99. doi: 10.1242/jcs.092262. Epub 2012 Jan 20.

5.

Clioquinol induces DNA double-strand breaks, activation of ATM, and subsequent activation of p53 signaling.

Katsuyama M, Iwata K, Ibi M, Matsuno K, Matsumoto M, Yabe-Nishimura C.

Toxicology. 2012 Sep 4;299(1):55-9. doi: 10.1016/j.tox.2012.05.013. Epub 2012 May 22.

PMID:
22627294
6.

Protein kinases that regulate chromosome stability and their downstream targets.

Nojima H.

Genome Dyn. 2006;1:131-48. doi: 10.1159/000092505. Review.

PMID:
18724058
7.

DNA-damage response during mitosis induces whole-chromosome missegregation.

Bakhoum SF, Kabeche L, Murnane JP, Zaki BI, Compton DA.

Cancer Discov. 2014 Nov;4(11):1281-9. doi: 10.1158/2159-8290.CD-14-0403. Epub 2014 Aug 8.

8.

Mitotic kinases: the key to duplication, segregation, and cytokinesis errors, chromosomal instability, and oncogenesis.

Li JJ, Li SA.

Pharmacol Ther. 2006 Sep;111(3):974-84. Epub 2006 Apr 17. Review.

PMID:
16603252
9.

Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity.

Goldstine JV, Nahas S, Gamo K, Gartler SM, Hansen RS, Roelfsema JH, Gatti RA, Marahrens Y.

DNA Repair (Amst). 2006 Apr 8;5(4):432-43. Epub 2006 Jan 19.

PMID:
16426903
10.

Widdrol activates DNA damage checkpoint through the signaling Chk2-p53-Cdc25A-p21-MCM4 pathway in HT29 cells.

Yun HJ, Hyun SK, Park JH, Kim BW, Kwon HJ.

Mol Cell Biochem. 2012 Apr;363(1-2):281-9. doi: 10.1007/s11010-011-1180-z. Epub 2011 Dec 11.

PMID:
22160829
11.

Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.

Tomimatsu N, Tahimic CG, Otsuki A, Burma S, Fukuhara A, Sato K, Shiota G, Oshimura M, Chen DJ, Kurimasa A.

J Biol Chem. 2007 Apr 6;282(14):10138-45. Epub 2007 Feb 1.

12.

[gamma H2AX in the recognition of DNA double-strand breaks].

Podhorecka M.

Postepy Hig Med Dosw (Online). 2009 Feb 27;63:92-8. Review. Polish.

13.

Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations.

Lee K, Zhang Y, Lee SE.

Nature. 2008 Jul 24;454(7203):543-6. doi: 10.1038/nature07054.

PMID:
18650924
14.

Breaks invisible to the DNA damage response machinery accumulate in ATM-deficient cells.

Martín M, Terradas M, Iliakis G, Tusell L, Genescà A.

Genes Chromosomes Cancer. 2009 Sep;48(9):745-59. doi: 10.1002/gcc.20679.

PMID:
19455703
15.
16.

E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.

Powers JT, Hong S, Mayhew CN, Rogers PM, Knudsen ES, Johnson DG.

Mol Cancer Res. 2004 Apr;2(4):203-14.

17.

Development of a high-content high-throughput screening assay for the discovery of ATM signaling inhibitors.

Bardelle C, Boros J.

J Biomol Screen. 2012 Aug;17(7):912-20. doi: 10.1177/1087057112448529. Epub 2012 May 31.

PMID:
22653913
18.
19.

Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair.

Gupta A, Yang Q, Pandita RK, Hunt CR, Xiang T, Misri S, Zeng S, Pagan J, Jeffery J, Puc J, Kumar R, Feng Z, Powell SN, Bhat A, Yaguchi T, Wadhwa R, Kaul SC, Parsons R, Khanna KK, Pandita TK.

Cell Cycle. 2009 Jul 15;8(14):2198-210. Epub 2009 Jul 7.

PMID:
19502790
20.

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.

Celli GB, de Lange T.

Nat Cell Biol. 2005 Jul;7(7):712-8. Epub 2005 Jun 19.

PMID:
15968270
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