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Results: 1 to 20 of 106

1.

Targeting the restricted α-subunit repertoire of airway smooth muscle GABAA receptors augments airway smooth muscle relaxation.

Gallos G, Yim P, Chang S, Zhang Y, Xu D, Cook JM, Gerthoffer WT, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2012 Jan 15;302(2):L248-56. doi: 10.1152/ajplung.00131.2011. Epub 2011 Sep 23.

PMID:
21949156
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol-mediated relaxation.

Gallos G, Gleason NR, Zhang Y, Pak SW, Sonett JR, Yang J, Emala CW.

Am J Physiol Lung Cell Mol Physiol. 2008 Dec;295(6):L1040-7. doi: 10.1152/ajplung.90330.2008. Epub 2008 Sep 12.

PMID:
18790991
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

GABAA receptors are expressed and facilitate relaxation in airway smooth muscle.

Mizuta K, Xu D, Pan Y, Comas G, Sonett JR, Zhang Y, Panettieri RA Jr, Yang J, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1206-16. doi: 10.1152/ajplung.00287.2007. Epub 2008 Apr 11.

PMID:
18408071
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Airway epithelium is a predominant source of endogenous airway GABA and contributes to relaxation of airway smooth muscle tone.

Gallos G, Townsend E, Yim P, Virag L, Zhang Y, Xu D, Bacchetta M, Emala CW.

Am J Physiol Lung Cell Mol Physiol. 2013 Feb 1;304(3):L191-7. doi: 10.1152/ajplung.00274.2012. Epub 2012 Nov 30.

PMID:
23204068
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Endogenous gamma-aminobutyric acid modulates tonic guinea pig airway tone and propofol-induced airway smooth muscle relaxation.

Gallos G, Gleason NR, Virag L, Zhang Y, Mizuta K, Whittington RA, Emala CW.

Anesthesiology. 2009 Apr;110(4):748-58.

PMID:
19322939
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Chloride in airway smooth muscle: the ignored anion no longer?

Gallos G, Yim P, Emala CW.

Am J Physiol Lung Cell Mol Physiol. 2012 Apr 15;302(8):L733-5. doi: 10.1152/ajplung.00053.2012. Epub 2012 Feb 17.

PMID:
22345576
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Gi-coupled γ-aminobutyric acid-B receptors cross-regulate phospholipase C and calcium in airway smooth muscle.

Mizuta K, Mizuta F, Xu D, Masaki E, Panettieri RA Jr, Emala CW.

Am J Respir Cell Mol Biol. 2011 Dec;45(6):1232-8. doi: 10.1165/rcmb.2011-0088OC. Epub 2011 Jun 30.

PMID:
21719794
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Recombinant GABAA receptor desensitization: the role of the gamma 2 subunit and its physiological significance.

Dominguez-Perrot C, Feltz P, Poulter MO.

J Physiol. 1996 Nov 15;497 ( Pt 1):145-59.

PMID:
8951718
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Activation of the midbrain periaqueductal gray induces airway smooth muscle relaxation.

Haxhiu MA, Yamamoto BK, Dreshaj IA, Ferguson DG.

J Appl Physiol (1985). 2002 Aug;93(2):440-9.

PMID:
12133848
[PubMed - indexed for MEDLINE]
Free Article
10.

Differentiation of functional adrenoceptors in human and guinea pig airways.

Zaagsma J, van der Heijden PJ, van der Schaar MW, Bank CM.

Eur J Respir Dis Suppl. 1984;135:16-33.

PMID:
6203772
[PubMed - indexed for MEDLINE]
11.

Characterization of the histamine receptors in the guinea-pig lung: evidence for relaxant histamine H3 receptors in the trachea.

Cardell LO, Edvinsson L.

Br J Pharmacol. 1994 Feb;111(2):445-54.

PMID:
7911715
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Functional expression of the GABAB receptor in human airway smooth muscle.

Osawa Y, Xu D, Sternberg D, Sonett JR, D'Armiento J, Panettieri RA, Emala CW.

Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L923-31. Epub 2006 Jul 7.

PMID:
16829628
[PubMed - indexed for MEDLINE]
Free Article
13.

The dopamine D(2) receptor is expressed and sensitizes adenylyl cyclase activity in airway smooth muscle.

Mizuta K, Zhang Y, Xu D, Masaki E, Panettieri RA Jr, Emala CW.

Am J Physiol Lung Cell Mol Physiol. 2012 Feb 1;302(3):L316-24. doi: 10.1152/ajplung.00130.2011. Epub 2011 Sep 30.

PMID:
21964403
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle.

Gallos G, Remy KE, Danielsson J, Funayama H, Fu XW, Chang HY, Yim P, Xu D, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2013 Nov 1;305(9):L625-34. doi: 10.1152/ajplung.00068.2013. Epub 2013 Aug 30.

PMID:
23997176
[PubMed - indexed for MEDLINE]
15.

Airway smooth muscle electrophysiology in a state of flux?

Janssen LJ.

Am J Physiol Lung Cell Mol Physiol. 2012 Apr 15;302(8):L730-2. doi: 10.1152/ajplung.00032.2012. Epub 2012 Feb 17.

PMID:
22345577
[PubMed - indexed for MEDLINE]
Free Article
16.

An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neurons.

Jia F, Pignataro L, Schofield CM, Yue M, Harrison NL, Goldstein PA.

J Neurophysiol. 2005 Dec;94(6):4491-501. Epub 2005 Sep 14.

PMID:
16162835
[PubMed - indexed for MEDLINE]
Free Article
17.

Epac as a novel effector of airway smooth muscle relaxation.

Roscioni SS, Maarsingh H, Elzinga CR, Schuur J, Menzen M, Halayko AJ, Meurs H, Schmidt M.

J Cell Mol Med. 2011 Jul;15(7):1551-63. doi: 10.1111/j.1582-4934.2010.01150.x.

PMID:
20716113
[PubMed - indexed for MEDLINE]
18.

The GABAA agonist muscimol attenuates induced airway constriction in guinea pigs in vivo.

Gleason NR, Gallos G, Zhang Y, Emala CW.

J Appl Physiol (1985). 2009 Apr;106(4):1257-63. doi: 10.1152/japplphysiol.91314.2008. Epub 2009 Feb 12.

PMID:
19213928
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

MaxiK channel mediates beta2-adrenoceptor-activated relaxation to isoprenaline through cAMP-dependent and -independent mechanisms in guinea-pig tracheal smooth muscle.

Tanaka Y, Yamashita Y, Yamaki F, Horinouchi T, Shigenobu K, Koike K.

J Smooth Muscle Res. 2003 Dec;39(6):205-19.

PMID:
15048013
[PubMed - indexed for MEDLINE]
Free Article
20.

Role of GABA receptors in the bronchial response: studies in sensitized guinea-pigs.

Tohda Y, Ohkawa K, Kubo H, Muraki M, Fukuoka M, Nakajima S.

Clin Exp Allergy. 1998 Jun;28(6):772-7.

PMID:
9677144
[PubMed - indexed for MEDLINE]

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