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Results: 1 to 20 of 120

1.

Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1.

Platta HW, Abrahamsen H, Thoresen SB, Stenmark H.

Biochem J. 2012 Jan 1;441(1):399-406. doi: 10.1042/BJ20111424.

PMID:
21936852
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes.

Vina-Vilaseca A, Sorkin A.

J Biol Chem. 2010 Mar 5;285(10):7645-56. doi: 10.1074/jbc.M109.058990. Epub 2010 Jan 5.

PMID:
20051513
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic.

Thoresen SB, Pedersen NM, Liestøl K, Stenmark H.

Exp Cell Res. 2010 Dec 10;316(20):3368-78. doi: 10.1016/j.yexcr.2010.07.008. Epub 2010 Jul 17.

PMID:
20643123
[PubMed - indexed for MEDLINE]
4.

The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation.

Wang C, An J, Zhang P, Xu C, Gao K, Wu D, Wang D, Yu H, Liu JO, Yu L.

Biochem J. 2012 Jun 1;444(2):279-89. doi: 10.1042/BJ20111983.

PMID:
22385262
[PubMed - indexed for MEDLINE]
Free Article
5.

Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression.

Abrahamsen H, Stenmark H, Platta HW.

FEBS Lett. 2012 Jun 4;586(11):1584-91. doi: 10.1016/j.febslet.2012.04.046. Epub 2012 May 3. Review.

PMID:
22673570
[PubMed - indexed for MEDLINE]
Free Article
6.

Regulation of the human ether-a-go-go-related gene (hERG) channel by Rab4 protein through neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2).

Cui Z, Zhang S.

J Biol Chem. 2013 Jul 26;288(30):21876-86. doi: 10.1074/jbc.M113.461715. Epub 2013 Jun 21.

PMID:
23792956
[PubMed - indexed for MEDLINE]
7.

NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway.

Eide PW, Cekaite L, Danielsen SA, Eilertsen IA, Kjenseth A, Fykerud TA, Ågesen TH, Bruun J, Rivedal E, Lothe RA, Leithe E.

Cell Signal. 2013 Jan;25(1):12-8. doi: 10.1016/j.cellsig.2012.08.012. Epub 2012 Sep 5.

PMID:
22974840
[PubMed - indexed for MEDLINE]
8.

The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.

Ahn Y, Hwang CY, Lee SR, Kwon KS, Lee C.

Biochem J. 2008 Jun 1;412(2):331-8. doi: 10.1042/BJ20071403.

PMID:
18307411
[PubMed - indexed for MEDLINE]
Free Article
9.

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination.

Xia P, Wang S, Du Y, Zhao Z, Shi L, Sun L, Huang G, Ye B, Li C, Dai Z, Hou N, Cheng X, Sun Q, Li L, Yang X, Fan Z.

EMBO J. 2013 Oct 16;32(20):2685-96. doi: 10.1038/emboj.2013.189. Epub 2013 Aug 23.

PMID:
23974797
[PubMed - indexed for MEDLINE]
Free Article
10.

Nedd4 and Nedd4-2: ubiquitin ligases at work in the neuron.

Donovan P, Poronnik P.

Int J Biochem Cell Biol. 2013 Mar;45(3):706-10. doi: 10.1016/j.biocel.2012.12.006. Epub 2012 Dec 20. Review.

PMID:
23262292
[PubMed - indexed for MEDLINE]
11.

Oncogenic role of the E3 ubiquitin ligase NEDD4-1, a PTEN negative regulator, in non-small-cell lung carcinomas.

Amodio N, Scrima M, Palaia L, Salman AN, Quintiero A, Franco R, Botti G, Pirozzi P, Rocco G, De Rosa N, Viglietto G.

Am J Pathol. 2010 Nov;177(5):2622-34. doi: 10.2353/ajpath.2010.091075. Epub 2010 Oct 1.

PMID:
20889565
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.

Skouloudaki K, Walz G.

PLoS One. 2012;7(4):e35735. doi: 10.1371/journal.pone.0035735. Epub 2012 Apr 27.

PMID:
22558212
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.

Itakura E, Kishi C, Inoue K, Mizushima N.

Mol Biol Cell. 2008 Dec;19(12):5360-72. doi: 10.1091/mbc.E08-01-0080. Epub 2008 Oct 8.

PMID:
18843052
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway.

Tofaris GK, Kim HT, Hourez R, Jung JW, Kim KP, Goldberg AL.

Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17004-9. doi: 10.1073/pnas.1109356108. Epub 2011 Sep 27.

PMID:
21953697
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels.

Rougier JS, Albesa M, Abriel H, Viard P.

J Biol Chem. 2011 Mar 18;286(11):8829-38. doi: 10.1074/jbc.M110.166520. Epub 2011 Jan 10.

PMID:
21220429
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Ndfip1 expression in developing neurons indicates a role for protein ubiquitination by Nedd4 E3 ligases during cortical development.

Goh CP, Low LH, Putz U, Gunnersen J, Hammond V, Howitt J, Tan SS.

Neurosci Lett. 2013 Oct 25;555:225-30. doi: 10.1016/j.neulet.2013.09.017. Epub 2013 Sep 13.

PMID:
24036464
[PubMed - indexed for MEDLINE]
17.

Phosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney development.

Terabayashi T, Sakaguchi M, Shinmyozu K, Ohshima T, Johjima A, Ogura T, Miki H, Nishinakamura R.

PLoS One. 2012;7(6):e39714. doi: 10.1371/journal.pone.0039714. Epub 2012 Jun 29.

PMID:
22768111
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Ubiquitylation of Fe65 adaptor protein by neuronal precursor cell expressed developmentally down regulated 4-2 (Nedd4-2) via the WW domain interaction with Fe65.

Lee EJ, Hyun S, Chun J, Shin SH, Kang SS.

Exp Mol Med. 2009 Aug 31;41(8):555-68. doi: 10.3858/emm.2009.41.8.061.

PMID:
19381069
[PubMed - indexed for MEDLINE]
Free PMC Article
19.
20.

Upregulation of SIRT1 by 17β-estradiol depends on ubiquitin-proteasome degradation of PPAR-γ mediated by NEDD4-1.

Han L, Wang P, Zhao G, Wang H, Wang M, Chen J, Tong T.

Protein Cell. 2013 Apr;4(4):310-21. doi: 10.1007/s13238-013-2124-z.

PMID:
23549616
[PubMed - indexed for MEDLINE]

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