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Self-renewal gene tracking to identify tumour-initiating cells associated with metastatic potential.

Darini CY, Pisani DF, Hofman P, Pedeutour F, Sudaka I, Chomienne C, Dani C, Ladoux A.

Oncogene. 2012 May 10;31(19):2438-49. doi: 10.1038/onc.2011.421. Epub 2011 Sep 19.


Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor.

Beltran AS, Rivenbark AG, Richardson BT, Yuan X, Quian H, Hunt JP, Zimmerman E, Graves LM, Blancafort P.

Breast Cancer Res. 2011 Sep 27;13(5):R94. doi: 10.1186/bcr3019.


CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis.

Gassenmaier M, Chen D, Buchner A, Henkel L, Schiemann M, Mack B, Schendel DJ, Zimmermann W, Pohla H.

Stem Cells. 2013 Aug;31(8):1467-76. doi: 10.1002/stem.1407.


Isolation of tumour stem-like cells from benign tumours.

Xu Q, Yuan X, Tunici P, Liu G, Fan X, Xu M, Hu J, Hwang JY, Farkas DL, Black KL, Yu JS.

Br J Cancer. 2009 Jul 21;101(2):303-11. doi: 10.1038/sj.bjc.6605142. Epub 2009 Jun 30.


OCT-4, an embryonic stem cell marker, is highly expressed in bladder cancer.

Atlasi Y, Mowla SJ, Ziaee SA, Bahrami AR.

Int J Cancer. 2007 Apr 1;120(7):1598-602.


Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells.

Chen YC, Hsu HS, Chen YW, Tsai TH, How CK, Wang CY, Hung SC, Chang YL, Tsai ML, Lee YY, Ku HH, Chiou SH.

PLoS One. 2008 Jul 9;3(7):e2637. doi: 10.1371/journal.pone.0002637.


Essential role for activation of the Polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer.

Berezovska OP, Glinskii AB, Yang Z, Li XM, Hoffman RM, Glinsky GV.

Cell Cycle. 2006 Aug;5(16):1886-901. Epub 2006 Aug 15.


STAT3 and Oct-3/4 control histone modification through induction of Eed in embryonic stem cells.

Ura H, Usuda M, Kinoshita K, Sun C, Mori K, Akagi T, Matsuda T, Koide H, Yokota T.

J Biol Chem. 2008 Apr 11;283(15):9713-23. doi: 10.1074/jbc.M707275200. Epub 2008 Jan 16.


Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis.

Botchkina IL, Rowehl RA, Rivadeneira DE, Karpeh MS Jr, Crawford H, Dufour A, Ju J, Wang Y, Leyfman Y, Botchkina GI.

Cancer Genomics Proteomics. 2009 Jan-Feb;6(1):19-29.


Screening for genes essential for mouse embryonic stem cell self-renewal using a subtractive RNA interference library.

Zhang JZ, Gao W, Yang HB, Zhang B, Zhu ZY, Xue YF.

Stem Cells. 2006 Dec;24(12):2661-8. Epub 2006 Sep 7.


Small nucleolar RNA signatures of lung tumor-initiating cells.

Mannoor K, Shen J, Liao J, Liu Z, Jiang F.

Mol Cancer. 2014 May 6;13:104. doi: 10.1186/1476-4598-13-104.


The reprogramming factor nuclear receptor subfamily 5, group A, member 2 cannot replace octamer-binding transcription factor 4 function in the self-renewal of embryonic stem cells.

Choi KW, Oh HR, Lee J, Lim B, Han YM, Oh J, Kim J.

FEBS J. 2014 Feb;281(4):1029-45. doi: 10.1111/febs.12665. Epub 2013 Dec 16.


The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling.

Ping YF, Yao XH, Jiang JY, Zhao LT, Yu SC, Jiang T, Lin MC, Chen JH, Wang B, Zhang R, Cui YH, Qian C, Wang Jm, Bian XW.

J Pathol. 2011 Jul;224(3):344-54. doi: 10.1002/path.2908. Epub 2011 May 27.


A CD90(+) tumor-initiating cell population with an aggressive signature and metastatic capacity in esophageal cancer.

Tang KH, Dai YD, Tong M, Chan YP, Kwan PS, Fu L, Qin YR, Tsao SW, Lung HL, Lung ML, Tong DK, Law S, Chan KW, Ma S, Guan XY.

Cancer Res. 2013 Apr 1;73(7):2322-32. doi: 10.1158/0008-5472.CAN-12-2991. Epub 2013 Feb 4.


Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells.

Chang CC, Shieh GS, Wu P, Lin CC, Shiau AL, Wu CL.

Cancer Res. 2008 Aug 1;68(15):6281-91. doi: 10.1158/0008-5472.CAN-08-0094.


Sphere culture of murine lung cancer cell lines are enriched with cancer initiating cells.

Morrison BJ, Steel JC, Morris JC.

PLoS One. 2012;7(11):e49752. doi: 10.1371/journal.pone.0049752. Epub 2012 Nov 13.


Overlapping genes may control reprogramming of mouse somatic cells into induced pluripotent stem cells (iPSCs) and breast cancer stem cells.

Mosca E, Cocola C, Sabour D, Pelucchi P, Bertalot G, Palumbo O, Carella M, Götte M, Schöler HR, Reinbold R, Zucchi I, Milanesi L.

In Silico Biol. 2010;10(5-6):207-21. doi: 10.3233/ISB-2010-0437.


Isolation and characterization of hepatic cancer cells with stem-like properties from hepatocellular carcinoma.

Tomuleasa C, Soritau O, Rus-Ciuca D, Pop T, Todea D, Mosteanu O, Pintea B, Foris V, Susman S, Kacsó G, Irimie A.

J Gastrointestin Liver Dis. 2010 Mar;19(1):61-7.


Neuron-like differentiation and selective ablation of undifferentiated embryonic stem cells containing suicide gene with Oct-4 promoter.

Hara A, Aoki H, Taguchi A, Niwa M, Yamada Y, Kunisada T, Mori H.

Stem Cells Dev. 2008 Aug;17(4):619-27. doi: 10.1089/scd.2007.0235.

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