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Washing red blood cells and platelets transfused in cardiac surgery reduces postoperative inflammation and number of transfusions: results of a prospective, randomized, controlled clinical trial.

Cholette JM, Henrichs KF, Alfieris GM, Powers KS, Phipps R, Spinelli SL, Swartz M, Gensini F, Daugherty LE, Nazarian E, Rubenstein JS, Sweeney D, Eaton M, Lerner NB, Blumberg N.

Pediatr Crit Care Med. 2012 May;13(3):290-9. doi: 10.1097/PCC.0b013e31822f173c.


Transfusion of cell saver salvaged blood in neonates and infants undergoing open heart surgery significantly reduces RBC and coagulant product transfusions and donor exposures: results of a prospective, randomized, clinical trial.

Cholette JM, Powers KS, Alfieris GM, Angona R, Henrichs KF, Masel D, Swartz MF, Daugherty LE, Belmont K, Blumberg N.

Pediatr Crit Care Med. 2013 Feb;14(2):137-47. doi: 10.1097/PCC.0b013e31826e741c.


Longer RBC storage duration is associated with increased postoperative infections in pediatric cardiac surgery.

Cholette JM, Pietropaoli AP, Henrichs KF, Alfieris GM, Powers KS, Phipps R, Spinelli SL, Swartz M, Gensini F, Daugherty LE, Nazarian E, Rubenstein JS, Sweeney D, Eaton M, Blumberg N.

Pediatr Crit Care Med. 2015 Mar;16(3):227-35. doi: 10.1097/PCC.0000000000000320.


Transfusion of washed red blood cells and platelets: what is left behind?.

Zabala L, Sheeran P, Kern FH.

Pediatr Crit Care Med. 2012 May;13(3):357-60. doi: 10.1097/PCC.0b013e318245c74e. No abstract available.


Washing of irradiated red blood cells prevents hyperkalaemia during cardiopulmonary bypass in neonates and infants undergoing surgery for complex congenital heart disease.

Swindell CG, Barker TA, McGuirk SP, Jones TJ, Barron DJ, Brawn WJ, Horsburgh A, Willetts RG.

Eur J Cardiothorac Surg. 2007 Apr;31(4):659-64. Epub 2007 Feb 8.


Duration of red blood cell storage and outcomes in pediatric cardiac surgery: an association found for pump prime blood.

Ranucci M, Carlucci C, Isgrò G, Boncilli A, De Benedetti D, De la Torre T, Brozzi S, Frigiola A.

Crit Care. 2009;13(6):R207. doi: 10.1186/cc8217. Epub 2009 Dec 21.


Use of modified ultrafiltration in adults undergoing coronary artery bypass grafting is associated with inflammatory modulation and less postoperative blood loss: a randomized and controlled study.

Torina AG, Silveira-Filho LM, Vilarinho KA, Eghtesady P, Oliveira PP, Sposito AC, Petrucci O.

J Thorac Cardiovasc Surg. 2012 Sep;144(3):663-70. doi: 10.1016/j.jtcvs.2012.04.012. Epub 2012 May 9.


Effects of allogeneic leukocytes in blood transfusions during cardiac surgery on inflammatory mediators and postoperative complications.

Bilgin YM, van de Watering LM, Versteegh MI, van Oers MH, Brand A.

Crit Care Med. 2010 Feb;38(2):546-52. doi: 10.1097/CCM.0b013e3181c0de7b.


The effectiveness of prestorage leukocyte-reduced red blood cell transfusion on perioperative inflammatory response with a miniaturized biocompatible bypass system.

Miyaji K, Miyamoto T, Kohira S, Itatani K, Tomoyasu T, Sato H, Ohara K.

J Thorac Cardiovasc Surg. 2010 Jun;139(6):1561-7. doi: 10.1016/j.jtcvs.2009.10.016. Epub 2009 Dec 28.


Effect of inhaled corticosteroid on pulmonary injury and inflammatory mediator production after cardiopulmonary bypass in children.

Santos AR, Heidemann SM, Walters HL 3rd, Delius RE.

Pediatr Crit Care Med. 2007 Sep;8(5):465-9.


Stress doses of hydrocortisone in high-risk patients undergoing cardiac surgery: effects on interleukin-6 to interleukin-10 ratio and early outcome.

Weis F, Beiras-Fernandez A, Schelling G, Briegel J, Lang P, Hauer D, Kreth S, Kaufmann I, Lamm P, Kilger E.

Crit Care Med. 2009 May;37(5):1685-90. doi: 10.1097/CCM.0b013e31819fca77.


Preoperative platelet dysfunction predicts blood product transfusion in children undergoing cardiac surgery.

Zubair MM, Bailly DK, Lantz G, Sunstrom RE, Saharan S, Boshkov LK, Sochacki P, Roger Hohimer A, Lasarev MR, Langley SM.

Interact Cardiovasc Thorac Surg. 2015 Jan;20(1):24-30. doi: 10.1093/icvts/ivu315. Epub 2014 Oct 3.


The indication for perioperative red blood cell transfusions is a predictive risk factor for severe postoperative morbidity and mortality in children undergoing cardiac surgery.

Willems A, Van Lerberghe C, Gonsette K, De Villé A, Melot C, Hardy JF, Van der Linden P.

Eur J Cardiothorac Surg. 2014 Jun;45(6):1050-7. doi: 10.1093/ejcts/ezt548. Epub 2014 Jan 14.


Association of complications with blood transfusions in pediatric cardiac surgery patients.

Iyengar A, Scipione CN, Sheth P, Ohye RG, Riegger L, Bove EL, Devaney EJ, Hirsch-Romano JC.

Ann Thorac Surg. 2013 Sep;96(3):910-6. doi: 10.1016/j.athoracsur.2013.05.003. Epub 2013 Jul 16.


Autologous platelet-rich plasma reduces transfusions during ascending aortic arch repair: a prospective, randomized, controlled trial.

Zhou SF, Estrera AL, Loubser P, Ignacio C, Panthayi S, Miller C 3rd, Sheinbaum R, Safi HJ.

Ann Thorac Surg. 2015 Apr;99(4):1282-90. doi: 10.1016/j.athoracsur.2014.11.007. Epub 2015 Feb 7.


Fresh whole blood versus reconstituted blood for pump priming in heart surgery in infants.

Mou SS, Giroir BP, Molitor-Kirsch EA, Leonard SR, Nikaidoh H, Nizzi F, Town DA, Roy LC, Scott W, Stromberg D.

N Engl J Med. 2004 Oct 14;351(16):1635-44.


Prophylactic peritoneal dialysis following cardiopulmonary bypass in children is associated with decreased inflammation and improved clinical outcomes.

Sasser WC, Dabal RJ, Askenazi DJ, Borasino S, Moellinger AB, Kirklin JK, Alten JA.

Congenit Heart Dis. 2014 Mar-Apr;9(2):106-15. doi: 10.1111/chd.12072. Epub 2013 May 7.


Angiotensin-converting enzyme inhibition alters the inflammatory and fibrinolytic response to cardiopulmonary bypass in children.

Fleming GA, Billings FT 4th, Klein TM, Bichell DP, Christian KG, Pretorius M.

Pediatr Crit Care Med. 2011 Sep;12(5):532-8. doi: 10.1097/PCC.0b013e3181fe3925.


Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial.

Bhutta AT, Schmitz ML, Swearingen C, James LP, Wardbegnoche WL, Lindquist DM, Glasier CM, Tuzcu V, Prodhan P, Dyamenahalli U, Imamura M, Jaquiss RD, Anand KJ.

Pediatr Crit Care Med. 2012 May;13(3):328-37. doi: 10.1097/PCC.0b013e31822f18f9.

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