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Items: 1 to 20 of 96

1.

Predicting the emetic liability of novel chemical entities: a comparative study.

Percie du Sert N, Holmes AM, Wallis R, Andrews PL.

Br J Pharmacol. 2012 Mar;165(6):1848-67. doi: 10.1111/j.1476-5381.2011.01669.x. Review.

2.

The broad-spectrum anti-emetic activity of the novel non-peptide tachykinin NK1 receptor antagonist GR203040.

Gardner CJ, Twissell DJ, Dale TJ, Gale JD, Jordan CC, Kilpatrick GJ, Bountra C, Ward P.

Br J Pharmacol. 1995 Dec;116(8):3158-63.

3.

Vomiting induction by ipecac syrup in dogs and ferrets.

Yamashita M, Yamashita M, Tanaka J, Chagi K, Takeda S, Kurihara T, Takeda Y, Fujii Y.

J Toxicol Sci. 1997 Dec;22(5):409-12.

PMID:
9442450
4.

Diphenidol has no actual broad antiemetic activity in dogs and ferrets.

Nakayama H, Yamakuni H, Nakayama A, Maeda Y, Imazumi K, Matsuo M, Mutoh S.

J Pharmacol Sci. 2004 Nov;96(3):301-6. Epub 2004 Nov 5.

5.

Olvanil: a non-pungent TRPV1 activator has anti-emetic properties in the ferret.

Chu KM, Ngan MP, Wai MK, Yeung CK, Andrews PL, Percie du Sert N, Rudd JA.

Neuropharmacology. 2010 Feb;58(2):383-91. doi: 10.1016/j.neuropharm.2009.10.002. Epub 2009 Oct 13.

PMID:
19825380
6.
7.

Cisplatin-induced emesis in the Ferret: a new animal model.

Florczyk AP, Schurig JE, Bradner WT.

Cancer Treat Rep. 1982 Jan;66(1):187-9.

PMID:
7198011
8.

Fluphenazine, ICS 205-930 and dl-fenfluramine differentially antagonise drug-induced emesis in the ferret.

Costall B, Domeney AM, Naylor RJ, Owera-Atepo JB, Rudd JA, Tattersall FD.

Neuropharmacology. 1990 May;29(5):453-62.

PMID:
1972549
9.

Comparison of three preclinical models for nausea and vomiting assessment.

Goineau S, Castagné V.

J Pharmacol Toxicol Methods. 2016 Jul 28;82:45-53. doi: 10.1016/j.vascn.2016.07.006. [Epub ahead of print]

PMID:
27477617
10.

Characterization of radiation-induced emesis in the ferret.

King GL.

Radiat Res. 1988 Jun;114(3):599-612.

PMID:
3375446
11.

Morphine 6-glucuronide: a metabolite of morphine with greater emetic potency than morphine in the ferret.

Thompson PI, Bingham S, Andrews PL, Patel N, Joel SP, Slevin ML.

Br J Pharmacol. 1992 May;106(1):3-8.

12.

Behavioral studies of emetic sensitivity in the ferret.

Knox AP, Strominger NL, Battles AH, Carpenter DO.

Brain Res Bull. 1993;31(5):477-84.

PMID:
8495372
13.

Animal models in the study of vomiting.

King GL.

Can J Physiol Pharmacol. 1990 Feb;68(2):260-8. Review.

PMID:
2178751
14.

Emesis induced by cisplatin in the ferret as a model for the detection of anti-emetic drugs.

Costall B, Domeney AM, Naylor RJ, Tattersall FD.

Neuropharmacology. 1987 Sep;26(9):1321-6.

PMID:
2890117
15.

Anti-emetic activity of ghrelin in ferrets exposed to the cytotoxic anti-cancer agent cisplatin.

Rudd JA, Ngan MP, Wai MK, King AG, Witherington J, Andrews PL, Sanger GJ.

Neurosci Lett. 2006 Jan 9;392(1-2):79-83. Epub 2005 Sep 22.

PMID:
16182445
16.

The identification of a novel phosphodiesterase 4 inhibitor, 1-ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (EPPA-1), with improved therapeutic index using pica feeding in rats as a measure of emetogenicity.

Davis TG, Peterson JJ, Kou JP, Capper-Spudich EA, Ball D, Nials AT, Wiseman J, Solanke YE, Lucas FS, Williamson RA, Ferrari L, Wren P, Knowles RG, Barnette MS, Podolin PL.

J Pharmacol Exp Ther. 2009 Sep;330(3):922-31. doi: 10.1124/jpet.109.152454. Epub 2009 Jun 4.

17.

Effects of lerisetron, a new 5-HT3 receptor antagonist, on ipecacuanha-induced emesis in healthy volunteers.

Cooper M, Sologuren A, Valiente R, Smith J.

Arzneimittelforschung. 2002;52(9):689-94.

PMID:
12404884
18.

Resiniferatoxin antagonizes cisplatin-induced emesis in dogs and ferrets.

Yamakuni H, Sawai-Nakayama H, Imazumi K, Maeda Y, Matsuo M, Manda T, Mutoh S.

Eur J Pharmacol. 2002 May 10;442(3):273-8.

PMID:
12065081
19.

The value of integrating pre-clinical data to predict nausea and vomiting risk in humans as illustrated by AZD3514, a novel androgen receptor modulator.

Grant C, Ewart L, Muthas D, Deavall D, Smith SA, Clack G, Newham P.

Toxicol Appl Pharmacol. 2016 Apr 1;296:10-8. doi: 10.1016/j.taap.2016.02.007. Epub 2016 Feb 11.

PMID:
26876616
20.

RG 12915: a potent 5-hydroxytryptamine-3 antagonist that is an orally effective inhibitor of cytotoxic drug-induced emesis in the ferret and dog.

Fitzpatrick LR, Lambert RM, Pendley CE, Martin GE, Bostwick JS, Gessner GW, Airey JE, Youssefyeh RD, Pendleton RG, Decktor DL.

J Pharmacol Exp Ther. 1990 Aug;254(2):450-5.

PMID:
2166791
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