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Results: 1 to 20 of 102

1.

Causal models for investigating complex genetic disease: II. what causal models can tell us about penetrance for additive, heterogeneity, and multiplicative two-locus models.

Madsen AM, Ottman R, Hodge SE.

Hum Hered. 2011;72(1):63-72. doi: 10.1159/000330780. Epub 2011 Sep 9.

PMID:
21912139
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Causal models for investigating complex disease: I. A primer.

Madsen AM, Hodge SE, Ottman R.

Hum Hered. 2011;72(1):54-62. doi: 10.1159/000330779. Epub 2011 Sep 9.

PMID:
21912138
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

How to model a complex trait. 2. Analysis with two disease loci.

Strauch K, Fimmers R, Baur MP, Wienker TF.

Hum Hered. 2003;56(4):200-11.

PMID:
15031621
[PubMed - indexed for MEDLINE]
Free Article
4.

Evidence for an interaction of schizophrenia susceptibility loci on chromosome 6q23.3 and 10q24.33-q26.13 in Arab Israeli families.

Alkelai A, Kohn Y, Olender T, Sarner-Kanyas K, Rigbi A, Hamdan A, Ben-Asher E, Lancet D, Lerer B.

Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5;150B(7):914-25. doi: 10.1002/ajmg.b.30918.

PMID:
19152384
[PubMed - indexed for MEDLINE]
5.

Direct power comparisons between simple LOD scores and NPL scores for linkage analysis in complex diseases.

Abreu PC, Greenberg DA, Hodge SE.

Am J Hum Genet. 1999 Sep;65(3):847-57.

PMID:
10441591
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Affected-sib-pair data can be used to distinguish two-locus heterogeneity from two-locus epistasis.

Cordell HJ.

Am J Hum Genet. 2003 Dec;73(6):1468-71; author reply 1471-3. No abstract available.

PMID:
14655099
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A complete enumeration and classification of two-locus disease models.

Li W, Reich J.

Hum Hered. 2000 Nov-Dec;50(6):334-49.

PMID:
10899752
[PubMed - indexed for MEDLINE]
Free Article
8.

Sample size needed to detect gene-gene interactions using linkage analysis.

Wang S, Zhao H.

Ann Hum Genet. 2007 Nov;71(Pt 6):828-42. Epub 2007 May 22.

PMID:
17521308
[PubMed - indexed for MEDLINE]
9.

Optimal ascertainment strategies to detect linkage to common disease alleles.

Badner JA, Gershon ES, Goldin LR.

Am J Hum Genet. 1998 Sep;63(3):880-8.

PMID:
9718337
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Linkage analysis under "random" and "genetic" reduced penetrance.

Greenberg DA, Hodge SE.

Genet Epidemiol. 1989;6(1):259-64.

PMID:
2786485
[PubMed - indexed for MEDLINE]
11.

Deriving components of genetic variance for multilocus models.

Tiwari HK, Elston RC.

Genet Epidemiol. 1997;14(6):1131-6.

PMID:
9433636
[PubMed - indexed for MEDLINE]
12.

Multi-locus penetrance variance analysis method for association study in complex diseases.

Sun X, Zhang Z, Zhang Y, Zhang X, Li Y.

Hum Hered. 2005;60(3):143-9. Epub 2005 Nov 24.

PMID:
16319491
[PubMed - indexed for MEDLINE]
Free Article
13.

Evaluating genetic heterogeneity in complex disorders.

Pal DK, Greenberg DA.

Hum Hered. 2002;53(4):216-26.

PMID:
12435885
[PubMed - indexed for MEDLINE]
Free Article
14.

Two-locus models of disease: comparison of likelihood and nonparametric linkage methods.

Goldin LR, Weeks DE.

Am J Hum Genet. 1993 Oct;53(4):908-15.

PMID:
8213819
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Strategy for detecting susceptibility genes with weak or no marginal effect.

Kotti S, Bickeboller H, Clerget-Darpoux F.

Hum Hered. 2007;63(2):85-92. Epub 2007 Feb 2. Erratum in: Hum Hered. 2008;65(2):119.

PMID:
17283437
[PubMed - indexed for MEDLINE]
Free Article
16.

Restrictions on components of variance for epistatic models.

Tiwari HK, Elston RC.

Theor Popul Biol. 1998 Oct;54(2):161-74.

PMID:
9733657
[PubMed - indexed for MEDLINE]
17.

Allelic penetrance approach as a tool to model two-locus interaction in complex binary traits.

Sepúlveda N, Paulino CD, Carneiro J, Penha-Gonçalves C.

Heredity (Edinb). 2007 Aug;99(2):173-84. Epub 2007 Jun 6.

PMID:
17551528
[PubMed - indexed for MEDLINE]
Free Article
18.

Linkage analysis of quantitative trait loci in the presence of heterogeneity.

Ekstrøm CT, Dalgaard P.

Hum Hered. 2003;55(1):16-26.

PMID:
12890922
[PubMed - indexed for MEDLINE]
Free Article
19.

Explorative two-locus linkage analysis suggests a multiplicative interaction between the 7q32 and 16p13 myoclonic seizures-related photosensitivity loci.

Pinto D, Kasteleijn-Nolst Trenité DG, Cordell HJ, Mattheisen M, Strauch K, Lindhout D, Koeleman BP.

Genet Epidemiol. 2007 Jan;31(1):42-50.

PMID:
17123300
[PubMed - indexed for MEDLINE]
20.

Regressive threshold model for familial analysis of complex diseases with variable age of onset.

Briollais L, Demenais F.

Genet Epidemiol. 2002 Nov;23(4):375-97.

PMID:
12432505
[PubMed - indexed for MEDLINE]

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