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Items: 1 to 20 of 98


Discrimination of membrane antigen affinity by B cells requires dominance of kinetic proofreading over serial engagement.

Tsourkas PK, Liu W, Das SC, Pierce SK, Raychaudhuri S.

Cell Mol Immunol. 2012 Jan;9(1):62-74. doi: 10.1038/cmi.2011.29. Epub 2011 Sep 12.


Formation of BCR oligomers provides a mechanism for B cell affinity discrimination.

Tsourkas PK, Somkanya C D, Yu-Yang P, Liu W, Pierce SK, Raychaudhuri S.

J Theor Biol. 2012 Aug 21;307:174-82. doi: 10.1016/j.jtbi.2012.05.008. Epub 2012 May 19.


Floating the raft hypothesis: the roles of lipid rafts in B cell antigen receptor function.

Cheng PC, Cherukuri A, Dykstra M, Malapati S, Sproul T, Chen MR, Pierce SK.

Semin Immunol. 2001 Apr;13(2):107-14. Review.


Antigen affinity discrimination is an intrinsic function of the B cell receptor.

Liu W, Meckel T, Tolar P, Sohn HW, Pierce SK.

J Exp Med. 2010 May 10;207(5):1095-111. doi: 10.1084/jem.20092123. Epub 2010 Apr 19.


Lipid rafts and B cell signaling.

Gupta N, DeFranco AL.

Semin Cell Dev Biol. 2007 Oct;18(5):616-26. Epub 2007 Jul 24. Review.


B cell ligand discrimination through a spreading and contraction response.

Fleire SJ, Goldman JP, Carrasco YR, Weber M, Bray D, Batista FD.

Science. 2006 May 5;312(5774):738-41.


Force generation in B-cell synapses: mechanisms coupling B-cell receptor binding to antigen internalization and affinity discrimination.

Tolar P, Spillane KM.

Adv Immunol. 2014;123:69-100. doi: 10.1016/B978-0-12-800266-7.00002-9. Review.


An analysis of B cell selection mechanisms in germinal centers.

Meyer-Hermann ME, Maini PK, Iber D.

Math Med Biol. 2006 Sep;23(3):255-77. Epub 2006 May 17.


Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.

Swanson CL, Wilson TJ, Strauch P, Colonna M, Pelanda R, Torres RM.

J Exp Med. 2010 Jul 5;207(7):1485-500. doi: 10.1084/jem.20092695. Epub 2010 Jun 21.


Targeting antigens to CD180 rapidly induces antigen-specific IgG, affinity maturation, and immunological memory.

Chaplin JW, Chappell CP, Clark EA.

J Exp Med. 2013 Sep 23;210(10):2135-46. doi: 10.1084/jem.20130188. Epub 2013 Sep 9.


Diacylglycerol kinase ΞΆ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responses.

Wheeler ML, Dong MB, Brink R, Zhong XP, DeFranco AL.

Sci Signal. 2013 Oct 15;6(297):ra91. doi: 10.1126/scisignal.2004189.


Models of signal transduction through the B-cell antigen receptor.

Geisberger R, Crameri R, Achatz G.

Immunology. 2003 Dec;110(4):401-10. Review. No abstract available.


Core fucosylation of IgG B cell receptor is required for antigen recognition and antibody production.

Li W, Yu R, Ma B, Yang Y, Jiao X, Liu Y, Cao H, Dong W, Liu L, Ma K, Fukuda T, Liu Q, Ma T, Wang Z, Gu J, Zhang J, Taniguchi N.

J Immunol. 2015 Mar 15;194(6):2596-606. doi: 10.4049/jimmunol.1402678. Epub 2015 Feb 18.


A detailed mathematical model predicts that serial engagement of IgE-Fc epsilon RI complexes can enhance Syk activation in mast cells.

Nag A, Monine MI, Blinov ML, Goldstein B.

J Immunol. 2010 Sep 15;185(6):3268-76. doi: 10.4049/jimmunol.1000326. Epub 2010 Aug 23.


Cutting edge: B cell antigen receptor signaling occurs outside lipid rafts in immature B cells.

Sproul TW, Malapati S, Kim J, Pierce SK.

J Immunol. 2000 Dec 1;165(11):6020-3.


Floating the raft hypothesis for immune receptors: access to rafts controls receptor signaling and trafficking.

Dykstra ML, Cherukuri A, Pierce SK.

Traffic. 2001 Mar;2(3):160-6. Review.


Early and dynamic polarization of T cell membrane rafts and constituents prior to TCR stop signals.

Van Komen JS, Mishra S, Byrum J, Chichili GR, Yaciuk JC, Farris AD, Rodgers W.

J Immunol. 2007 Nov 15;179(10):6845-55.


Coalescence of B cell receptor and invariant chain MHC II in a raft-like membrane domain.

Hauser JT, Lindner R.

J Leukoc Biol. 2014 Nov;96(5):843-55. doi: 10.1189/jlb.2A0713-353R. Epub 2014 Jul 14.

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