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Items: 1 to 20 of 180

1.

Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked inhibitor of apoptosis protein (XIAP) to promote survival of Epstein-Barr virus+ (EBV+) B cell lymphomas.

Hatton O, Phillips LK, Vaysberg M, Hurwich J, Krams SM, Martinez OM.

J Biol Chem. 2011 Oct 28;286(43):37368-78. doi: 10.1074/jbc.M111.255125. Epub 2011 Sep 9.

2.

Syk-induced phosphatidylinositol-3-kinase activation in Epstein-Barr virus posttransplant lymphoproliferative disorder.

Hatton O, Lambert SL, Phillips LK, Vaysberg M, Natkunam Y, Esquivel CO, Krams SM, Martinez OM.

Am J Transplant. 2013 Apr;13(4):883-90. doi: 10.1111/ajt.12137. Epub 2013 Feb 7.

3.

Src kinase and Syk activation initiate PI3K signaling by a chimeric latent membrane protein 1 in Epstein-Barr virus (EBV)+ B cell lymphomas.

Hatton O, Lambert SL, Krams SM, Martinez OM.

PLoS One. 2012;7(8):e42610. doi: 10.1371/journal.pone.0042610. Epub 2012 Aug 3.

4.

PI3Kδ inhibition augments the efficacy of rapamycin in suppressing proliferation of Epstein-Barr virus (EBV)+ B cell lymphomas.

Furukawa S, Wei L, Krams SM, Esquivel CO, Martinez OM.

Am J Transplant. 2013 Aug;13(8):2035-43. doi: 10.1111/ajt.12328. Epub 2013 Jul 10.

5.

The Epstein-Barr virus causes epithelial-mesenchymal transition in human corneal epithelial cells via Syk/src and Akt/Erk signaling pathways.

Park GB, Kim D, Kim YS, Kim S, Lee HK, Yang JW, Hur DY.

Invest Ophthalmol Vis Sci. 2014 Mar 20;55(3):1770-9. doi: 10.1167/iovs.13-12988.

PMID:
24569586
6.

Membrane-associated signaling in human B-lymphoma lines.

Tauzin S, Ding H, Burdevet D, Borisch B, Hoessli DC.

Exp Cell Res. 2011 Jan 15;317(2):151-62. doi: 10.1016/j.yexcr.2010.09.011. Epub 2010 Sep 25.

PMID:
20875408
7.

Epstein-Barr virus latent membrane protein-2A induces ITAM/Syk- and Akt-dependent epithelial migration through αv-integrin membrane translocation.

Fotheringham JA, Coalson NE, Raab-Traub N.

J Virol. 2012 Oct;86(19):10308-20. doi: 10.1128/JVI.00853-12. Epub 2012 Jul 25.

9.

Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway.

Swart R, Ruf IK, Sample J, Longnecker R.

J Virol. 2000 Nov;74(22):10838-45.

10.

LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells.

Shin JY, Kim JO, Lee SK, Chae HS, Kang JH.

BMC Cancer. 2010 Aug 13;10:425. doi: 10.1186/1471-2407-10-425.

11.

SYK regulates mTOR signaling in AML.

Carnevale J, Ross L, Puissant A, Banerji V, Stone RM, DeAngelo DJ, Ross KN, Stegmaier K.

Leukemia. 2013 Nov;27(11):2118-28. doi: 10.1038/leu.2013.89. Epub 2013 Mar 28.

12.

(-)-Epigallocatechin-3-gallate inhibition of Epstein-Barr virus spontaneous lytic infection involves ERK1/2 and PI3-K/Akt signaling in EBV-positive cells.

Liu S, Li H, Chen L, Yang L, Li L, Tao Y, Li W, Li Z, Liu H, Tang M, Bode AM, Dong Z, Cao Y.

Carcinogenesis. 2013 Mar;34(3):627-37. doi: 10.1093/carcin/bgs364. Epub 2012 Nov 24.

13.

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells.

Longo PG, Laurenti L, Gobessi S, Sica S, Leone G, Efremov DG.

Blood. 2008 Jan 15;111(2):846-55. Epub 2007 Oct 10.

14.

A20 (TNFAIP3) deletion in Epstein-Barr virus-associated lymphoproliferative disorders/lymphomas.

Ando M, Sato Y, Takata K, Nomoto J, Nakamura S, Ohshima K, Takeuchi T, Orita Y, Kobayashi Y, Yoshino T.

PLoS One. 2013;8(2):e56741. doi: 10.1371/journal.pone.0056741. Epub 2013 Feb 13.

15.

The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulation.

Jeon YK, Park CH, Kim KY, Li YC, Kim J, Kim YA, Paik JH, Park BK, Kim CW, Kim YN.

J Pathol. 2007 Oct;213(2):170-9.

PMID:
17768706
17.

Emerging therapeutic strategies for Epstein-Barr virus+ post-transplant lymphoproliferative disorder.

Hatton O, Martinez OM, Esquivel CO.

Pediatr Transplant. 2012 May;16(3):220-9. doi: 10.1111/j.1399-3046.2012.01656.x. Epub 2012 Feb 21. Review.

18.

Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia.

Buchner M, Baer C, Prinz G, Dierks C, Burger M, Zenz T, Stilgenbauer S, Jumaa H, Veelken H, Zirlik K.

Blood. 2010 Jun 3;115(22):4497-506. doi: 10.1182/blood-2009-07-233692. Epub 2010 Mar 24.

19.
20.

Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells.

Morrison JA, Klingelhutz AJ, Raab-Traub N.

J Virol. 2003 Nov;77(22):12276-84.

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