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Results: 1 to 20 of 99

1.

Exploiting bias in a non-immune human antibody library to predict antigenicity.

Ackerman ME, Lai JI, Pastan I, Wittrup KD.

Protein Eng Des Sel. 2011 Nov;24(11):845-53. doi: 10.1093/protein/gzr046. Epub 2011 Sep 9.

PMID:
21908549
[PubMed - indexed for MEDLINE]
Free Article
2.

Optimal construction of non-immune scFv phage display libraries from mouse bone marrow and spleen established to select specific scFvs efficiently binding to antigen.

Okamoto T, Mukai Y, Yoshioka Y, Shibata H, Kawamura M, Yamamoto Y, Nakagawa S, Kamada H, Hayakawa T, Mayumi T, Tsutsumi Y.

Biochem Biophys Res Commun. 2004 Oct 15;323(2):583-91.

PMID:
15369791
[PubMed - indexed for MEDLINE]
3.

Synthetic single-framework antibody library integrated with rapid affinity maturation by VL shuffling.

Brockmann EC, Akter S, Savukoski T, Huovinen T, Lehmusvuori A, Leivo J, Saavalainen O, Azhayev A, Lövgren T, Hellman J, Lamminmäki U.

Protein Eng Des Sel. 2011 Sep;24(9):691-700. doi: 10.1093/protein/gzr023. Epub 2011 Jun 16.

PMID:
21680620
[PubMed - indexed for MEDLINE]
Free Article
4.

Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays.

Chan CE, Chan AH, Lim AP, Hanson BJ.

J Immunol Methods. 2011 Oct 28;373(1-2):79-88. doi: 10.1016/j.jim.2011.08.005. Epub 2011 Aug 12.

PMID:
21856306
[PubMed - indexed for MEDLINE]
5.

Generation of a stable anti-human CD44v6 scFv and analysis of its cancer-targeting ability in vitro.

Chen Y, Huang K, Li X, Lin X, Zhu Z, Wu Y.

Cancer Immunol Immunother. 2010 Jun;59(6):933-42. doi: 10.1007/s00262-010-0819-z. Epub 2010 Mar 12.

PMID:
20224978
[PubMed - indexed for MEDLINE]
6.

Phage versus phagemid libraries for generation of human monoclonal antibodies.

O'Connell D, Becerril B, Roy-Burman A, Daws M, Marks JD.

J Mol Biol. 2002 Aug 2;321(1):49-56.

PMID:
12139932
[PubMed - indexed for MEDLINE]
7.

High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries.

Fellouse FA, Esaki K, Birtalan S, Raptis D, Cancasci VJ, Koide A, Jhurani P, Vasser M, Wiesmann C, Kossiakoff AA, Koide S, Sidhu SS.

J Mol Biol. 2007 Nov 2;373(4):924-40. Epub 2007 Aug 19.

PMID:
17825836
[PubMed - indexed for MEDLINE]
8.

Isolation of functional single domain antibody by whole cell immunization: implications for cancer treatment.

Baral TN, Murad Y, Nguyen TD, Iqbal U, Zhang J.

J Immunol Methods. 2011 Aug 31;371(1-2):70-80. doi: 10.1016/j.jim.2011.06.017. Epub 2011 Jun 30.

PMID:
21741385
[PubMed - indexed for MEDLINE]
9.

Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC.

Repp R, Kellner C, Muskulus A, Staudinger M, Nodehi SM, Glorius P, Akramiene D, Dechant M, Fey GH, van Berkel PH, van de Winkel JG, Parren PW, Valerius T, Gramatzki M, Peipp M.

J Immunol Methods. 2011 Oct 28;373(1-2):67-78. doi: 10.1016/j.jim.2011.08.003. Epub 2011 Aug 9.

PMID:
21855548
[PubMed - indexed for MEDLINE]
10.

The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.

Rothe C, Urlinger S, Löhning C, Prassler J, Stark Y, Jäger U, Hubner B, Bardroff M, Pradel I, Boss M, Bittlingmaier R, Bataa T, Frisch C, Brocks B, Honegger A, Urban M.

J Mol Biol. 2008 Feb 29;376(4):1182-200. doi: 10.1016/j.jmb.2007.12.018. Epub 2007 Dec 15.

PMID:
18191144
[PubMed - indexed for MEDLINE]
11.

Simplified synthetic antibody libraries.

Rajan S, Sidhu SS.

Methods Enzymol. 2012;502:3-23. doi: 10.1016/B978-0-12-416039-2.00001-X.

PMID:
22208979
[PubMed - indexed for MEDLINE]
12.

Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent.

Beiboer SH, Reurs A, Roovers RC, Arends JW, Whitelegg NR, Rees AR, Hoogenboom HR.

J Mol Biol. 2000 Feb 25;296(3):833-49.

PMID:
10677285
[PubMed - indexed for MEDLINE]
13.

Specificity grafting of human antibody frameworks selected from a phage display library: generation of a highly stable humanized anti-CD22 single-chain Fv fragment.

Krauss J, Arndt MA, Martin AC, Liu H, Rybak SM.

Protein Eng. 2003 Oct;16(10):753-9.

PMID:
14600205
[PubMed - indexed for MEDLINE]
Free Article
14.

A large human domain antibody library combining heavy and light chain CDR3 diversity.

Chen W, Zhu Z, Feng Y, Dimitrov DS.

Mol Immunol. 2010 Jan;47(4):912-21. doi: 10.1016/j.molimm.2009.09.039. Epub 2009 Nov 1.

PMID:
19883941
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Discovery of diverse and functional antibodies from large human repertoire antibody libraries.

Schwimmer LJ, Huang B, Giang H, Cotter RL, Chemla-Vogel DS, Dy FV, Tam EM, Zhang F, Toy P, Bohmann DJ, Watson SR, Beaber JW, Reddy N, Kuan HF, Bedinger DH, Rondon IJ.

J Immunol Methods. 2013 May 31;391(1-2):60-71. doi: 10.1016/j.jim.2013.02.010. Epub 2013 Feb 27.

PMID:
23454004
[PubMed - indexed for MEDLINE]
Free Article
16.

A V(L) single-domain antibody library shows a high-propensity to yield non-aggregating binders.

Hussack G, Keklikian A, Alsughayyir J, Hanifi-Moghaddam P, Arbabi-Ghahroudi M, van Faassen H, Hou ST, Sad S, MacKenzie R, Tanha J.

Protein Eng Des Sel. 2012 Jun;25(6):313-8. doi: 10.1093/protein/gzs014. Epub 2012 Apr 6.

PMID:
22490957
[PubMed - indexed for MEDLINE]
Free Article
17.

Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-beta oligomers.

Meli G, Visintin M, Cannistraci I, Cattaneo A.

J Mol Biol. 2009 Apr 3;387(3):584-606. doi: 10.1016/j.jmb.2009.01.061. Epub 2009 Feb 4.

PMID:
19361429
[PubMed - indexed for MEDLINE]
18.

Construction of a large phage-displayed human antibody domain library with a scaffold based on a newly identified highly soluble, stable heavy chain variable domain.

Chen W, Zhu Z, Feng Y, Xiao X, Dimitrov DS.

J Mol Biol. 2008 Oct 10;382(3):779-89. doi: 10.1016/j.jmb.2008.07.054. Epub 2008 Jul 26.

PMID:
18687338
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning.

Klimka A, Matthey B, Roovers RC, Barth S, Arends JW, Engert A, Hoogenboom HR.

Br J Cancer. 2000 Jul;83(2):252-60.

PMID:
10901379
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Molecular characterization of the circulating anti-HIV-1 gp120-specific B cell repertoire using antibody phage display libraries generated from pre-selected HIV-1 gp120 binding PBLs.

Koefoed K, Farnaes L, Wang M, Svejgaard A, Burton DR, Ditzel HJ.

J Immunol Methods. 2005 Feb;297(1-2):187-201. Epub 2005 Jan 27.

PMID:
15777942
[PubMed - indexed for MEDLINE]

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