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Results: 1 to 20 of 134

1.

Leishmania donovani encodes a functional enzyme involved in vitamin C biosynthesis: arabino-1,4-lactone oxidase.

Biyani N, Madhubala R.

Mol Biochem Parasitol. 2011 Dec;180(2):76-85. doi: 10.1016/j.molbiopara.2011.08.005. Epub 2011 Sep 3.

PMID:
21907739
[PubMed - indexed for MEDLINE]
2.

Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase.

Wolucka BA, Communi D.

FEBS J. 2006 Oct;273(19):4435-45. Epub 2006 Sep 5.

PMID:
16956367
[PubMed - indexed for MEDLINE]
3.

Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-gamma-lactone oxidase.

Ha MN, Graham FL, D'Souza CK, Muller WJ, Igdoura SA, Schellhorn HE.

Genomics. 2004 Mar;83(3):482-92.

PMID:
14962674
[PubMed - indexed for MEDLINE]
4.

Vitamin C biosynthesis in trypanosomes: a role for the glycosome.

Wilkinson SR, Prathalingam SR, Taylor MC, Horn D, Kelly JM.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11645-50. Epub 2005 Aug 8.

PMID:
16087875
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani.

Chawla B, Kumar RR, Tyagi N, Subramanian G, Srinivasan N, Park MH, Madhubala R.

PLoS One. 2012;7(3):e33138. doi: 10.1371/journal.pone.0033138. Epub 2012 Mar 16.

PMID:
22438895
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Cloning, overexpression and characterization of Leishmania donovani squalene synthase.

Bhargava P, Kumar K, Chaudhaery SS, Saxena AK, Roy U.

FEMS Microbiol Lett. 2010 Oct;311(1):82-92. doi: 10.1111/j.1574-6968.2010.02071.x. Epub 2010 Aug 16.

PMID:
20722739
[PubMed - indexed for MEDLINE]
7.

Identification and characterization of a novel Ribose 5-phosphate isomerase B from Leishmania donovani.

Kaur PK, Dinesh N, Soumya N, Babu NK, Singh S.

Biochem Biophys Res Commun. 2012 Apr 27;421(1):51-6. doi: 10.1016/j.bbrc.2012.03.107. Epub 2012 Mar 29.

PMID:
22483752
[PubMed - indexed for MEDLINE]
8.
9.

L-ascorbic acid biosynthesis.

Smirnoff N.

Vitam Horm. 2001;61:241-66. Review.

PMID:
11153268
[PubMed - indexed for MEDLINE]
10.

Characterization of the gene encoding glyoxalase II from Leishmania donovani: a potential target for anti-parasite drugs.

Padmanabhan PK, Mukherjee A, Madhubala R.

Biochem J. 2006 Jan 1;393(Pt 1):227-34.

PMID:
16159313
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Molecular basis for the deficiency in humans of gulonolactone oxidase, a key enzyme for ascorbic acid biosynthesis.

Nishikimi M, Yagi K.

Am J Clin Nutr. 1991 Dec;54(6 Suppl):1203S-1208S. Review.

PMID:
1962571
[PubMed - indexed for MEDLINE]
Free Article
12.

Isolation and characterization of cDNA sequences of L-gulono-gamma-lactone oxidase, a key enzyme for biosynthesis of ascorbic acid, from extant primitive fish groups.

Cho YS, Douglas SE, Gallant JW, Kim KY, Kim DS, Nam YK.

Comp Biochem Physiol B Biochem Mol Biol. 2007 Jun;147(2):178-90. Epub 2007 Jan 24.

PMID:
17317254
[PubMed - indexed for MEDLINE]
13.

A missense mutation of L-gulono-gamma-lactone oxidase causes the inability of scurvy-prone osteogenic disorder rats to synthesize L-ascorbic acid.

Kawai T, Nishikimi M, Ozawa T, Yagi K.

J Biol Chem. 1992 Oct 25;267(30):21973-6.

PMID:
1400508
[PubMed - indexed for MEDLINE]
Free Article
14.

Characterisation of the gene encoding type II DNA topoisomerase from Leishmania donovani: a key molecular target in antileishmanial therapy.

Das A, Dasgupta A, Sharma S, Ghosh M, Sengupta T, Bandopadhyay S, Majumder HK.

Nucleic Acids Res. 2001 May 1;29(9):1844-51.

PMID:
11328867
[PubMed - indexed for MEDLINE]
Free PMC Article
15.
16.

Molecular cloning, biochemical and structural analysis of elongation factor-1 alpha from Leishmania donovani: comparison with the mammalian homologue.

Nandan D, Cherkasov A, Sabouti R, Yi T, Reiner NE.

Biochem Biophys Res Commun. 2003 Mar 21;302(4):646-52.

PMID:
12646217
[PubMed - indexed for MEDLINE]
17.

Cloning and chromosomal mapping of the human nonfunctional gene for L-gulono-gamma-lactone oxidase, the enzyme for L-ascorbic acid biosynthesis missing in man.

Nishikimi M, Fukuyama R, Minoshima S, Shimizu N, Yagi K.

J Biol Chem. 1994 May 6;269(18):13685-8.

PMID:
8175804
[PubMed - indexed for MEDLINE]
Free Article
18.

Cloning and expression of a Leishmania donovani gene instructed by a peptide isolated from major histocompatibility complex class II molecules of infected macrophages.

Campos-Neto A, Soong L, Cordova JL, Sant'Angelo D, Skeiky YA, Ruddle NH, Reed SG, Janeway C Jr, McMahon-Pratt D.

J Exp Med. 1995 Nov 1;182(5):1423-33.

PMID:
7595213
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Glyoxalase I from Leishmania donovani: a potential target for anti-parasite drug.

Padmanabhan PK, Mukherjee A, Singh S, Chattopadhyaya S, Gowri VS, Myler PJ, Srinivasan N, Madhubala R.

Biochem Biophys Res Commun. 2005 Dec 2;337(4):1237-48. Epub 2005 Oct 7.

PMID:
16236261
[PubMed - indexed for MEDLINE]
20.

A biochemical and genetic study of Leishmania donovani pyruvate kinase.

Sandoval W, Isea R, Rodriguez E, Ramirez JL.

Gene. 2008 Nov 15;424(1-2):25-32. doi: 10.1016/j.gene.2008.07.034. Epub 2008 Aug 3.

PMID:
18725273
[PubMed - indexed for MEDLINE]

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