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Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells.

Grüning NM, Rinnerthaler M, Bluemlein K, Mülleder M, Wamelink MM, Lehrach H, Jakobs C, Breitenbach M, Ralser M.

Cell Metab. 2011 Sep 7;14(3):415-27. doi: 10.1016/j.cmet.2011.06.017.


Negative Feedback of Glycolysis and Oxidative Phosphorylation: Mechanisms of and Reasons for It.

Sokolov SS, Balakireva AV, Markova OV, Severin FF.

Biochemistry (Mosc). 2015 May;80(5):559-64. doi: 10.1134/S0006297915050065.


Metabolic reconfiguration of the central glucose metabolism: a crucial strategy of Leishmania donovani for its survival during oxidative stress.

Ghosh AK, Sardar AH, Mandal A, Saini S, Abhishek K, Kumar A, Purkait B, Singh R, Das S, Mukhopadhyay R, Roy S, Das P.

FASEB J. 2015 May;29(5):2081-98. doi: 10.1096/fj.14-258624. Epub 2015 Feb 17.


Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast.

Dephoure N, Hwang S, O'Sullivan C, Dodgson SE, Gygi SP, Amon A, Torres EM.

Elife. 2014 Jul 29;3:e03023. doi: 10.7554/eLife.03023.


Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis.

Grüning NM, Du D, Keller MA, Luisi BF, Ralser M.

Open Biol. 2014 Mar 5;4:130232. doi: 10.1098/rsob.130232.


Differential regulation of mitochondrial pyruvate carrier genes modulates respiratory capacity and stress tolerance in yeast.

Timón-Gómez A, Proft M, Pascual-Ahuir A.

PLoS One. 2013 Nov 14;8(11):e79405. doi: 10.1371/journal.pone.0079405. eCollection 2013.


Tuning the range and stability of multiple phenotypic states with coupled positive-negative feedback loops.

Avendaño MS, Leidy C, Pedraza JM.

Nat Commun. 2013;4:2605. doi: 10.1038/ncomms3605.


ML285 affects reactive oxygen species’ inhibition of pyruvate kinase M2.

Brimacombe KR, Anastasiou D, Hong BS, Tempel W, Dimov S, Veith H, Auld DS, Vander Heiden MG, Thomas CJ, Park HW, Shen M, Cantley LC, Boxer MB.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Aug 3 [updated 2013 May 8].


Catabolite regulation analysis of Escherichia coli for acetate overflow mechanism and co-consumption of multiple sugars based on systems biology approach using computer simulation.

Matsuoka Y, Shimizu K.

J Biotechnol. 2013 Oct 20;168(2):155-73. doi: 10.1016/j.jbiotec.2013.06.023. Epub 2013 Jul 10.


Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.

Iqbal MA, Siddiqui FA, Gupta V, Chattopadhyay S, Gopinath P, Kumar B, Manvati S, Chaman N, Bamezai RN.

Mol Cancer. 2013 Jul 9;12:72. doi: 10.1186/1476-4598-12-72.


A reversible Warburg effect is induced by Theileria parasites to transform host leukocytes.

Medjkane S, Weitzman JB.

Cell Cycle. 2013 Jul 15;12(14):2167-8. No abstract available.


Mn²⁺/Mg ²⁺-dependent pyruvate kinase from a D-lactic acid-producing bacterium Sporolactobacillus inulinus: characterization of a novel Mn²⁺-mediated allosterically regulated enzyme.

Zheng L, Xu T, Bai Z, He B.

Appl Microbiol Biotechnol. 2014 Feb;98(4):1583-93. doi: 10.1007/s00253-013-4907-9. Epub 2013 May 22.


Temporal system-level organization of the switch from glycolytic to gluconeogenic operation in yeast.

Zampar GG, Kümmel A, Ewald J, Jol S, Niebel B, Picotti P, Aebersold R, Sauer U, Zamboni N, Heinemann M.

Mol Syst Biol. 2013;9:651. doi: 10.1038/msb.2013.11.


Why are chlorinated pollutants so difficult to degrade aerobically? Redox stress limits 1,3-dichloroprop-1-ene metabolism by Pseudomonas pavonaceae.

Nikel PI, Pérez-Pantoja D, de Lorenzo V.

Philos Trans R Soc Lond B Biol Sci. 2013 Mar 11;368(1616):20120377. doi: 10.1098/rstb.2012.0377. Print 2013 Apr 19.


Early mitochondrial dysfunction leads to altered redox chemistry underlying pathogenesis of TPI deficiency.

Hrizo SL, Fisher IJ, Long DR, Hutton JA, Liu Z, Palladino MJ.

Neurobiol Dis. 2013 Jun;54:289-96. doi: 10.1016/j.nbd.2012.12.020. Epub 2013 Jan 12.


Broad distribution of TPI-GAPDH fusion proteins among eukaryotes: evidence for glycolytic reactions in the mitochondrion?

Nakayama T, Ishida K, Archibald JM.

PLoS One. 2012;7(12):e52340. doi: 10.1371/journal.pone.0052340. Epub 2012 Dec 20.


Energetic coupling between an oxidizable cysteine and the phosphorylatable N-terminus of human liver pyruvate kinase.

Holyoak T, Zhang B, Deng J, Tang Q, Prasannan CB, Fenton AW.

Biochemistry. 2013 Jan 22;52(3):466-76. doi: 10.1021/bi301341r. Epub 2013 Jan 11.


M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth.

Cortés-Cros M, Hemmerlin C, Ferretti S, Zhang J, Gounarides JS, Yin H, Muller A, Haberkorn A, Chene P, Sellers WR, Hofmann F.

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):489-94. doi: 10.1073/pnas.1212780110. Epub 2012 Dec 24.


Evaluation of control mechanisms for Saccharomyces cerevisiae central metabolic reactions using metabolome data of eight single-gene deletion mutants.

Shirai T, Matsuda F, Okamoto M, Kondo A.

Appl Microbiol Biotechnol. 2013 Apr;97(8):3569-77. doi: 10.1007/s00253-012-4597-8. Epub 2012 Dec 7.

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