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Results: 1 to 20 of 98

1.

SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance.

Ramadori G, Fujikawa T, Anderson J, Berglund ED, Frazao R, Michán S, Vianna CR, Sinclair DA, Elias CF, Coppari R.

Cell Metab. 2011 Sep 7;14(3):301-12. doi: 10.1016/j.cmet.2011.06.014.

PMID:
21907137
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.

Klöckener T, Hess S, Belgardt BF, Paeger L, Verhagen LA, Husch A, Sohn JW, Hampel B, Dhillon H, Zigman JM, Lowell BB, Williams KW, Elmquist JK, Horvath TL, Kloppenburg P, Brüning JC.

Nat Neurosci. 2011 Jun 5;14(7):911-8. doi: 10.1038/nn.2847.

PMID:
21642975
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity.

Ramadori G, Fujikawa T, Fukuda M, Anderson J, Morgan DA, Mostoslavsky R, Stuart RC, Perello M, Vianna CR, Nillni EA, Rahmouni K, Coppari R.

Cell Metab. 2010 Jul 7;12(1):78-87. doi: 10.1016/j.cmet.2010.05.010.

PMID:
20620997
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight.

Zhang R, Dhillon H, Yin H, Yoshimura A, Lowell BB, Maratos-Flier E, Flier JS.

Endocrinology. 2008 Nov;149(11):5654-61. doi: 10.1210/en.2008-0805. Epub 2008 Jul 31.

PMID:
18669597
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity.

Funato H, Tsai AL, Willie JT, Kisanuki Y, Williams SC, Sakurai T, Yanagisawa M.

Cell Metab. 2009 Jan 7;9(1):64-76. doi: 10.1016/j.cmet.2008.10.010.

PMID:
19117547
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Role of orexin in the regulation of glucose homeostasis.

Tsuneki H, Wada T, Sasaoka T.

Acta Physiol (Oxf). 2010 Mar;198(3):335-48. doi: 10.1111/j.1748-1716.2009.02008.x. Epub 2009 May 28. Review.

PMID:
19489767
[PubMed - indexed for MEDLINE]
7.

Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance.

Leinninger GM, Opland DM, Jo YH, Faouzi M, Christensen L, Cappellucci LA, Rhodes CJ, Gnegy ME, Becker JB, Pothos EN, Seasholtz AF, Thompson RC, Myers MG Jr.

Cell Metab. 2011 Sep 7;14(3):313-23. doi: 10.1016/j.cmet.2011.06.016.

PMID:
21907138
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Metabolic actions of hypothalamic SIRT1.

Coppari R.

Trends Endocrinol Metab. 2012 Apr;23(4):179-85. doi: 10.1016/j.tem.2012.01.002. Epub 2012 Feb 28. Review.

PMID:
22382036
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction.

Schenk S, McCurdy CE, Philp A, Chen MZ, Holliday MJ, Bandyopadhyay GK, Osborn O, Baar K, Olefsky JM.

J Clin Invest. 2011 Nov;121(11):4281-8. doi: 10.1172/JCI58554. Epub 2011 Oct 10.

PMID:
21985785
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Amylin improves the effect of leptin on insulin sensitivity in leptin-resistant diet-induced obese mice.

Kusakabe T, Ebihara K, Sakai T, Miyamoto L, Aotani D, Yamamoto Y, Yamamoto-Kataoka S, Aizawa-Abe M, Fujikura J, Hosoda K, Nakao K.

Am J Physiol Endocrinol Metab. 2012 Apr 15;302(8):E924-31. doi: 10.1152/ajpendo.00198.2011. Epub 2012 Jan 24.

PMID:
22275759
[PubMed - indexed for MEDLINE]
Free Article
11.

Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding.

Purushotham A, Xu Q, Li X.

FASEB J. 2012 Feb;26(2):656-67. doi: 10.1096/fj.11-195172. Epub 2011 Oct 17.

PMID:
22006157
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ablation of Sim1 neurons causes obesity through hyperphagia and reduced energy expenditure.

Xi D, Gandhi N, Lai M, Kublaoui BM.

PLoS One. 2012;7(4):e36453. doi: 10.1371/journal.pone.0036453. Epub 2012 Apr 27.

PMID:
22558467
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.

Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S Jr, Elmquist JK, Lowell BB.

Neuron. 2006 Jan 19;49(2):191-203.

PMID:
16423694
[PubMed - indexed for MEDLINE]
Free Article
14.

Effects of body weight and alcohol consumption on insulin sensitivity.

Paulson QX, Hong J, Holcomb VB, Nunez NP.

Nutr J. 2010 Mar 22;9:14. doi: 10.1186/1475-2891-9-14.

PMID:
20307313
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced obese mice.

Lee SJ, Verma S, Simonds SE, Kirigiti MA, Kievit P, Lindsley SR, Loche A, Smith MS, Cowley MA, Grove KL.

J Neurosci. 2013 Sep 18;33(38):15306-17. doi: 10.1523/JNEUROSCI.0837-13.2013.

PMID:
24048859
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation.

Feige JN, Lagouge M, Canto C, Strehle A, Houten SM, Milne JC, Lambert PD, Mataki C, Elliott PJ, Auwerx J.

Cell Metab. 2008 Nov;8(5):347-58. doi: 10.1016/j.cmet.2008.08.017. Erratum in: Cell Metab. 2009 Feb;9(2):210.

PMID:
19046567
[PubMed - indexed for MEDLINE]
Free Article
17.

The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1.

Yang Z, Wang X, He Y, Qi L, Yu L, Xue B, Shi H.

PLoS One. 2012;7(11):e49935. doi: 10.1371/journal.pone.0049935. Epub 2012 Nov 21.

PMID:
23183898
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons.

Cristino L, Busetto G, Imperatore R, Ferrandino I, Palomba L, Silvestri C, Petrosino S, Orlando P, Bentivoglio M, Mackie K, Di Marzo V.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):E2229-38. doi: 10.1073/pnas.1219485110. Epub 2013 Apr 29.

PMID:
23630288
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice.

Li H, Xu M, Lee J, He C, Xie Z.

Am J Physiol Endocrinol Metab. 2012 Nov 15;303(10):E1234-44. doi: 10.1152/ajpendo.00198.2012. Epub 2012 Sep 11.

PMID:
22967499
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

An obligate role of oxytocin neurons in diet induced energy expenditure.

Wu Z, Xu Y, Zhu Y, Sutton AK, Zhao R, Lowell BB, Olson DP, Tong Q.

PLoS One. 2012;7(9):e45167. doi: 10.1371/journal.pone.0045167. Epub 2012 Sep 18.

PMID:
23028821
[PubMed - indexed for MEDLINE]
Free PMC Article
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