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Results: 1 to 20 of 102

1.

HCN2 ion channels play a central role in inflammatory and neuropathic pain.

Emery EC, Young GT, Berrocoso EM, Chen L, McNaughton PA.

Science. 2011 Sep 9;333(6048):1462-6. doi: 10.1126/science.1206243.

PMID:
21903816
[PubMed - indexed for MEDLINE]
Free Article
2.

A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain.

Hildebrand ME, Smith PL, Bladen C, Eduljee C, Xie JY, Chen L, Fee-Maki M, Doering CJ, Mezeyova J, Zhu Y, Belardetti F, Pajouhesh H, Parker D, Arneric SP, Parmar M, Porreca F, Tringham E, Zamponi GW, Snutch TP.

Pain. 2011 Apr;152(4):833-43. doi: 10.1016/j.pain.2010.12.035. Epub 2011 Feb 23.

PMID:
21349638
[PubMed - indexed for MEDLINE]
3.

Spontaneous pain, both neuropathic and inflammatory, is related to frequency of spontaneous firing in intact C-fiber nociceptors.

Djouhri L, Koutsikou S, Fang X, McMullan S, Lawson SN.

J Neurosci. 2006 Jan 25;26(4):1281-92.

PMID:
16436616
[PubMed - indexed for MEDLINE]
Free Article
4.

Expression and properties of hyperpolarization-activated current in rat dorsal root ganglion neurons with known sensory function.

Gao LL, McMullan S, Djouhri L, Acosta C, Harper AA, Lawson SN.

J Physiol. 2012 Oct 1;590(Pt 19):4691-705. doi: 10.1113/jphysiol.2012.238485. Epub 2012 Jul 2.

PMID:
22753545
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Chronic inflammatory pain is associated with increased excitability and hyperpolarization-activated current (Ih) in C- but not Aδ-nociceptors.

Weng X, Smith T, Sathish J, Djouhri L.

Pain. 2012 Apr;153(4):900-14. doi: 10.1016/j.pain.2012.01.019. Epub 2012 Feb 28.

PMID:
22377439
[PubMed - indexed for MEDLINE]
6.

HCN1 and HCN2 in Rat DRG neurons: levels in nociceptors and non-nociceptors, NT3-dependence and influence of CFA-induced skin inflammation on HCN2 and NT3 expression.

Acosta C, McMullan S, Djouhri L, Gao L, Watkins R, Berry C, Dempsey K, Lawson SN.

PLoS One. 2012;7(12):e50442. doi: 10.1371/journal.pone.0050442. Epub 2012 Dec 7.

PMID:
23236374
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Divergent peripheral effects of pituitary adenylate cyclase-activating polypeptide-38 on nociception in rats and mice.

Sándor K, Bölcskei K, McDougall JJ, Schuelert N, Reglodi D, Elekes K, Petho G, Pintér E, Szolcsányi J, Helyes Z.

Pain. 2009 Jan;141(1-2):143-50. doi: 10.1016/j.pain.2008.10.028. Epub 2008 Dec 16.

PMID:
19091468
[PubMed - indexed for MEDLINE]
8.

HCN2 ion channels: an emerging role as the pacemakers of pain.

Emery EC, Young GT, McNaughton PA.

Trends Pharmacol Sci. 2012 Aug;33(8):456-63. doi: 10.1016/j.tips.2012.04.004. Epub 2012 May 19. Review.

PMID:
22613784
[PubMed - indexed for MEDLINE]
9.

Regulation of firing frequency in nociceptive neurons by pro-inflammatory mediators.

Momin A, McNaughton PA.

Exp Brain Res. 2009 Jun;196(1):45-52. doi: 10.1007/s00221-009-1744-2. Epub 2009 Apr 7. Review.

PMID:
19350231
[PubMed - indexed for MEDLINE]
10.

A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats.

Zhang XF, Shieh CC, Chapman ML, Matulenko MA, Hakeem AH, Atkinson RN, Kort ME, Marron BE, Joshi S, Honore P, Faltynek CR, Krafte DS, Jarvis MF.

Neuropharmacology. 2010 Sep;59(3):201-7. doi: 10.1016/j.neuropharm.2010.05.009. Epub 2010 Jun 1.

PMID:
20566409
[PubMed - indexed for MEDLINE]
11.

Inhibition of peripheral vanilloid TRPV1 receptors reduces noxious heat-evoked responses of dorsal horn neurons in naïve, carrageenan-inflamed and neuropathic rats.

Jhaveri MD, Elmes SJ, Kendall DA, Chapman V.

Eur J Neurosci. 2005 Jul;22(2):361-70.

PMID:
16045489
[PubMed - indexed for MEDLINE]
12.

Mechanical and heat sensitization of cutaneous nociceptors after peripheral inflammation in the rat.

Andrew D, Greenspan JD.

J Neurophysiol. 1999 Nov;82(5):2649-56.

PMID:
10561434
[PubMed - indexed for MEDLINE]
Free Article
13.

The cell and molecular basis of mechanical, cold, and inflammatory pain.

Abrahamsen B, Zhao J, Asante CO, Cendan CM, Marsh S, Martinez-Barbera JP, Nassar MA, Dickenson AH, Wood JN.

Science. 2008 Aug 1;321(5889):702-5. doi: 10.1126/science.1156916.

PMID:
18669863
[PubMed - indexed for MEDLINE]
Free Article
14.

Mechanical and heat sensitization of cutaneous nociceptors in rats with experimental peripheral neuropathy.

Shim B, Kim DW, Kim BH, Nam TS, Leem JW, Chung JM.

Neuroscience. 2005;132(1):193-201.

PMID:
15780478
[PubMed - indexed for MEDLINE]
15.

Nociception and TRP Channels.

Numazaki M, Tominaga M.

Curr Drug Targets CNS Neurol Disord. 2004 Dec;3(6):479-85. Review.

PMID:
15578965
[PubMed - indexed for MEDLINE]
16.

Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain.

Chaplan SR, Guo HQ, Lee DH, Luo L, Liu C, Kuei C, Velumian AA, Butler MP, Brown SM, Dubin AE.

J Neurosci. 2003 Feb 15;23(4):1169-78.

PMID:
12598605
[PubMed - indexed for MEDLINE]
Free Article
17.

Dependence of hyperpolarisation-activated cyclic nucleotide-gated channel activity on basal cyclic adenosine monophosphate production in spontaneously firing GH3 cells.

Kretschmannova K, Gonzalez-Iglesias AE, Tomić M, Stojilkovic SS.

J Neuroendocrinol. 2006 Jul;18(7):484-93.

PMID:
16774497
[PubMed - indexed for MEDLINE]
18.

Heat hyperalgesia after incision requires TRPV1 and is distinct from pure inflammatory pain.

Pogatzki-Zahn EM, Shimizu I, Caterina M, Raja SN.

Pain. 2005 Jun;115(3):296-307. Epub 2005 Apr 20.

PMID:
15911156
[PubMed - indexed for MEDLINE]
19.

Marked attenuation of inflammatory mediator-induced C-fiber sensitization for mechanical and hypotonic stimuli in TRPV4-/- mice.

Chen X, Alessandri-Haber N, Levine JD.

Mol Pain. 2007 Oct 29;3:31.

PMID:
17967183
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.

Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q.

Neuron. 2006 Feb 2;49(3):365-77.

PMID:
16446141
[PubMed - indexed for MEDLINE]
Free Article

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