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A directed protein interaction network for investigating intracellular signal transduction.

Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE.

Sci Signal. 2011 Sep 6;4(189):rs8. doi: 10.1126/scisignal.2001699.


Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition.

Shin SY, Rath O, Zebisch A, Choo SM, Kolch W, Cho KH.

Cancer Res. 2010 Sep 1;70(17):6715-24. doi: 10.1158/0008-5472.CAN-10-1377. Epub 2010 Aug 24.


Protein evolution on a human signaling network.

Cui Q, Purisima EO, Wang E.

BMC Syst Biol. 2009 Feb 18;3:21. doi: 10.1186/1752-0509-3-21.


Causal protein-signaling networks derived from multiparameter single-cell data.

Sachs K, Perez O, Pe'er D, Lauffenburger DA, Nolan GP.

Science. 2005 Apr 22;308(5721):523-9. Erratum in: Science. 2005 Aug 19;309(5738):1187.


Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain.

Engelman JA, Chu C, Lin A, Jo H, Ikezu T, Okamoto T, Kohtz DS, Lisanti MP.

FEBS Lett. 1998 May 29;428(3):205-11.


Functional proteomics mapping of a human signaling pathway.

Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM.

Genome Res. 2004 Jul;14(7):1324-32.


The potential for signal integration and processing in interacting MAP kinase cascades.

Schwacke JH, Voit EO.

J Theor Biol. 2007 Jun 21;246(4):604-20. Epub 2007 Jan 14.


Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

Tong J, Taylor P, Peterman SM, Prakash A, Moran MF.

Mol Cell Proteomics. 2009 Sep;8(9):2131-44. doi: 10.1074/mcp.M900148-MCP200. Epub 2009 Jun 15.


Integration of G protein signals by extracellular signal-regulated protein kinases in SK-N-MC neuroepithelioma cells.

Chan AS, Yeung WW, Wong YH.

J Neurochem. 2005 Sep;94(5):1457-70. Epub 2005 Jun 30.


Global protein-protein interaction network in the human pathogen Mycobacterium tuberculosis H37Rv.

Wang Y, Cui T, Zhang C, Yang M, Huang Y, Li W, Zhang L, Gao C, He Y, Li Y, Huang F, Zeng J, Huang C, Yang Q, Tian Y, Zhao C, Chen H, Zhang H, He ZG.

J Proteome Res. 2010 Dec 3;9(12):6665-77. doi: 10.1021/pr100808n. Epub 2010 Nov 10.


Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.

Wallach T, Schellenberg K, Maier B, Kalathur RK, Porras P, Wanker EE, Futschik ME, Kramer A.

PLoS Genet. 2013 Mar;9(3):e1003398. doi: 10.1371/journal.pgen.1003398. Epub 2013 Mar 28.


Causal inference in biomolecular pathways using a Bayesian network approach and an Implicit method.

Ben Hassen H, Masmoudi A, Rebai A.

J Theor Biol. 2008 Aug 21;253(4):717-24. doi: 10.1016/j.jtbi.2008.04.030. Epub 2008 May 4.


Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP).

Meyer zu Schwabedissen HE, Grube M, Dreisbach A, Jedlitschky G, Meissner K, Linnemann K, Fusch C, Ritter CA, Völker U, Kroemer HK.

Drug Metab Dispos. 2006 Apr;34(4):524-33. Epub 2006 Jan 13.


A framework for elucidating regulatory networks based on prior information and expression data.

Gevaert O, Van Vooren S, De Moor B.

Ann N Y Acad Sci. 2007 Dec;1115:240-8. Epub 2007 Oct 9.

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