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Delineation of a core RNA element required for Kaposi's sarcoma-associated herpesvirus ORF57 binding and activity.

Sei E, Conrad NK.

Virology. 2011 Oct 25;419(2):107-16. doi: 10.1016/j.virol.2011.08.006. Epub 2011 Sep 1.


Kaposi's sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncoding RNA from cellular RNA decay pathways.

Sahin BB, Patel D, Conrad NK.

PLoS Pathog. 2010 Mar 5;6(3):e1000799. doi: 10.1371/journal.ppat.1000799.


Kaposi's sarcoma-associated herpesvirus ORF57 protein enhances mRNA accumulation independently of effects on nuclear RNA export.

Nekorchuk M, Han Z, Hsieh TT, Swaminathan S.

J Virol. 2007 Sep;81(18):9990-8. Epub 2007 Jul 3.


Kaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59.

Majerciak V, Uranishi H, Kruhlak M, Pilkington GR, Massimelli MJ, Bear J, Pavlakis GN, Felber BK, Zheng ZM.

J Virol. 2011 Feb;85(4):1528-40. doi: 10.1128/JVI.01709-10. Epub 2010 Nov 24.


Stability of a long noncoding viral RNA depends on a 9-nt core element at the RNA 5' end to interact with viral ORF57 and cellular PABPC1.

Massimelli MJ, Kang JG, Majerciak V, Le SY, Liewehr DJ, Steinberg SM, Zheng ZM.

Int J Biol Sci. 2011;7(8):1145-60. Epub 2011 Oct 16.


Chromatin immunoprecipitation and microarray analysis suggest functional cooperation between Kaposi's Sarcoma-associated herpesvirus ORF57 and K-bZIP.

Hunter OV, Sei E, Richardson RB, Conrad NK.

J Virol. 2013 Apr;87(7):4005-16. doi: 10.1128/JVI.03459-12. Epub 2013 Jan 30.


A posttranscriptional regulator of Kaposi's sarcoma-associated herpesvirus interacts with RNA-binding protein PCBP1 and controls gene expression through the IRES.

Nishimura K, Ueda K, Guwanan E, Sakakibara S, Do E, Osaki E, Yada K, Okuno T, Yamanishi K.

Virology. 2004 Aug 1;325(2):364-78.


Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.

Majerciak V, Zheng ZM.

Front Biosci (Landmark Ed). 2009 Jan 1;14:1516-28. Review.


Interplay between polyadenylate-binding protein 1 and Kaposi's sarcoma-associated herpesvirus ORF57 in accumulation of polyadenylated nuclear RNA, a viral long noncoding RNA.

Massimelli MJ, Majerciak V, Kruhlak M, Zheng ZM.

J Virol. 2013 Jan;87(1):243-56. doi: 10.1128/JVI.01693-12. Epub 2012 Oct 17.


Kaposi's sarcoma-associated herpesvirus ORF57 is not a bona fide export factor.

Pilkington GR, Majerciak V, Bear J, Uranishi H, Zheng ZM, Felber BK.

J Virol. 2012 Dec;86(23):13089-94. doi: 10.1128/JVI.00606-12. Epub 2012 Sep 19.


Identification of the physiological gene targets of the essential lytic replicative Kaposi's sarcoma-associated herpesvirus ORF57 protein.

Verma D, Li DJ, Krueger B, Renne R, Swaminathan S.

J Virol. 2015 Feb;89(3):1688-702. doi: 10.1128/JVI.02663-14. Epub 2014 Nov 19.


Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

Boyne JR, Colgan KJ, Whitehouse A.

PLoS Pathog. 2008 Oct;4(10):e1000194. doi: 10.1371/journal.ppat.1000194. Epub 2008 Oct 31.


Kaposi's sarcoma-associated herpesvirus ORF57 promotes escape of viral and human interleukin-6 from microRNA-mediated suppression.

Kang JG, Pripuzova N, Majerciak V, Kruhlak M, Le SY, Zheng ZM.

J Virol. 2011 Mar;85(6):2620-30. doi: 10.1128/JVI.02144-10. Epub 2011 Jan 5.


Mutation of a C-terminal motif affects Kaposi's sarcoma-associated herpesvirus ORF57 RNA binding, nuclear trafficking, and multimerization.

Taylor A, Jackson BR, Noerenberg M, Hughes DJ, Boyne JR, Verow M, Harris M, Whitehouse A.

J Virol. 2011 Aug;85(15):7881-91. doi: 10.1128/JVI.00138-11. Epub 2011 May 18.


Kaposi's sarcoma-associated herpesvirus ORF57 functions as a viral splicing factor and promotes expression of intron-containing viral lytic genes in spliceosome-mediated RNA splicing.

Majerciak V, Yamanegi K, Allemand E, Kruhlak M, Krainer AR, Zheng ZM.

J Virol. 2008 Mar;82(6):2792-801. doi: 10.1128/JVI.01856-07. Epub 2008 Jan 9.

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