Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 110

1.

Overexpression of the HIF hydroxylases PHD1, PHD2, PHD3 and FIH are individually and collectively unfavorable prognosticators for NSCLC survival.

Andersen S, Donnem T, Stenvold H, Al-Saad S, Al-Shibli K, Busund LT, Bremnes RM.

PLoS One. 2011;6(8):e23847. doi: 10.1371/journal.pone.0023847. Epub 2011 Aug 22.

2.

DNA methylation analysis of the HIF-1α prolyl hydroxylase domain genes PHD1, PHD2, PHD3 and the factor inhibiting HIF gene FIH in invasive breast carcinomas.

Huang KT, Mikeska T, Dobrovic A, Fox SB.

Histopathology. 2010 Sep;57(3):451-60. doi: 10.1111/j.1365-2559.2010.03633.x. Epub 2010 Aug 19.

PMID:
20727020
3.

Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer.

Rawluszko AA, Bujnicka KE, Horbacka K, Krokowicz P, Jagodziński PP.

BMC Cancer. 2013 Nov 6;13:526. doi: 10.1186/1471-2407-13-526.

4.

BRCA1 tumours correlate with a HIF-1alpha phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expression.

Yan M, Rayoo M, Takano EA; KConFab Investigators, Fox SB.

Br J Cancer. 2009 Oct 6;101(7):1168-74. doi: 10.1038/sj.bjc.6605287. Epub 2009 Sep 1. Erratum in: Br J Cancer. 2009 Nov 17;101(10):1806. Thorne, H [removed].

5.

Expressions of individual PHDs associate with good prognostic factors and increased proliferation in breast cancer patients.

Peurala E, Koivunen P, Bloigu R, Haapasaari KM, Jukkola-Vuorinen A.

Breast Cancer Res Treat. 2012 May;133(1):179-88. doi: 10.1007/s10549-011-1750-5. Epub 2011 Aug 30.

PMID:
21877141
6.

[The expression of hypoxia-inducible factor-1alpha and its hydroxylases in pulmonary arteries of patient with chronic obstructive pulmonary disease].

Chen YR, Dai AG, Hu RC, Kong CC.

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2012 May;28(3):234-8. Chinese.

PMID:
22860423
7.

Low expression of prolyl hydroxylase 2 is associated with tumor grade and poor prognosis in patients with colorectal cancer.

Xie G, Zheng L, Ou J, Huang H, He J, Li J, Pan F, Liang H.

Exp Biol Med (Maywood). 2012 Jul;237(7):860-6. doi: 10.1258/ebm.2012.011331. Epub 2012 Jul 16.

PMID:
22802519
8.

Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness.

Jokilehto T, Rantanen K, Luukkaa M, Heikkinen P, Grenman R, Minn H, Kronqvist P, Jaakkola PM.

Clin Cancer Res. 2006 Feb 15;12(4):1080-7.

9.

Expression of key hypoxia sensing prolyl-hydroxylases PHD1, -2 and -3 in pancreaticobiliary cancer.

Gossage L, Zaitoun A, Fareed KR, Turley H, Aloysius M, Lobo DN, Harris AL, Madhusudan S.

Histopathology. 2010 Jun;56(7):908-20. doi: 10.1111/j.1365-2559.2010.03566.x. Epub 2010 May 15.

PMID:
20497244
10.

Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway.

Giatromanolaki A, Koukourakis MI, Pezzella F, Turley H, Sivridis E, Bouros D, Bougioukas G, Harris AL, Gatter KC.

Cancer Lett. 2008 Apr 8;262(1):87-93. doi: 10.1016/j.canlet.2007.11.041. Epub 2008 Jan 9.

PMID:
18187257
11.

Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.

Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto T, Wagner T, Jelkmann W, Jaakkola P, Metzen E.

Biochem J. 2004 Aug 1;381(Pt 3):761-7.

12.

Overexpression of the HIF hydroxylase PHD3 is a favorable prognosticator for gastric cancer.

Su C, Huang K, Sun L, Yang D, Zheng H, Gao C, Tong J, Zhang Q.

Med Oncol. 2012 Dec;29(4):2710-5.

PMID:
22290580
13.

The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen.

Fox SB, Generali D, Berruti A, Brizzi MP, Campo L, Bonardi S, Bersiga A, Allevi G, Milani M, Aguggini S, Mele T, Dogliotti L, Bottini A, Harris AL.

Breast Cancer Res. 2011 Feb 3;13(1):R16. doi: 10.1186/bcr2825.

14.

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.

Metzen E, Berchner-Pfannschmidt U, Stengel P, Marxsen JH, Stolze I, Klinger M, Huang WQ, Wotzlaw C, Hellwig-Bürgel T, Jelkmann W, Acker H, Fandrey J.

J Cell Sci. 2003 Apr 1;116(Pt 7):1319-26.

15.

Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors.

Henze AT, Riedel J, Diem T, Wenner J, Flamme I, Pouyseggur J, Plate KH, Acker T.

Cancer Res. 2010 Jan 1;70(1):357-66. doi: 10.1158/0008-5472.CAN-09-1876. Epub 2009 Dec 22.

16.

[Reciprocal regulation between hypoxia-inducible factor-1alpha and its prolyl hydroxylases in hypoxic pulmonary hypertension rats].

Chen YR, Dai AG, Hu RC.

Zhonghua Jie He He Hu Xi Za Zhi. 2006 Oct;29(10):668-73. Chinese.

PMID:
17129494
18.

Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.

Tarhonskaya H, Hardy AP, Howe EA, Loik ND, Kramer HB, McCullagh JS, Schofield CJ, Flashman E.

J Biol Chem. 2015 Aug 7;290(32):19726-42. doi: 10.1074/jbc.M115.653014. Epub 2015 Jun 25.

19.

Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.

Aprelikova O, Chandramouli GV, Wood M, Vasselli JR, Riss J, Maranchie JK, Linehan WM, Barrett JC.

J Cell Biochem. 2004 Jun 1;92(3):491-501. Erratum in: J Cell Biochem. 2004 Oct 15;93(3):639.

PMID:
15156561
20.
Items per page

Supplemental Content

Write to the Help Desk