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Acetate scavenging activity in Escherichia coli: interplay of acetyl-CoA synthetase and the PEP-glyoxylate cycle in chemostat cultures.

Renilla S, Bernal V, Fuhrer T, Castaño-Cerezo S, Pastor JM, Iborra JL, Sauer U, Cánovas M. Renilla S, et al. Appl Microbiol Biotechnol. 2012 Mar;93(5):2109-24. doi: 10.1007/s00253-011-3536-4. Epub 2011 Sep 1. Appl Microbiol Biotechnol. 2012. PMID: 21881893

Catabolite regulation analysis of Escherichia coli for acetate overflow mechanism and co-consumption of multiple sugars based on systems biology approach using computer simulation.

Matsuoka Y, Shimizu K. Matsuoka Y, et al. J Biotechnol. 2013 Oct 20;168(2):155-73. doi: 10.1016/j.jbiotec.2013.06.023. Epub 2013 Jul 10. J Biotechnol. 2013. PMID: 23850830

Characterizing the effect of expression of an acetyl-CoA synthetase insensitive to acetylation on co-utilization of glucose and acetate in batch and continuous cultures of E. coli W.

Novak K, Flöckner L, Erian AM, Freitag P, Herwig C, Pflügl S. Novak K, et al. Microb Cell Fact. 2018 Jul 9;17(1):109. doi: 10.1186/s12934-018-0955-2. Microb Cell Fact. 2018. PMID: 29986728 Free PMC article.

Characterization of mutants of the yeast Yarrowia lipolytica defective in acetyl-coenzyme A synthetase.

Kujau M, Weber H, Barth G. Kujau M, et al. Yeast. 1992 Mar;8(3):193-203. doi: 10.1002/yea.320080305. Yeast. 1992. PMID: 1349449

Glucose metabolism at high density growth of E. coli B and E. coli K: differences in metabolic pathways are responsible for efficient glucose utilization in E. coli B as determined by microarrays and Northern blot analyses.

Phue JN, Noronha SB, Hattacharyya R, Wolfe AJ, Shiloach J. Phue JN, et al. Biotechnol Bioeng. 2005 Jun 30;90(7):805-20. doi: 10.1002/bit.20478. Biotechnol Bioeng. 2005. PMID: 15806547

Acetyl-CoA synthetase overexpression in Escherichia coli demonstrates more efficient acetate assimilation and lower acetate accumulation: a potential tool in metabolic engineering.

Lin H, Castro NM, Bennett GN, San KY. Lin H, et al. Appl Microbiol Biotechnol. 2006 Aug;71(6):870-4. doi: 10.1007/s00253-005-0230-4. Epub 2006 Feb 22. Appl Microbiol Biotechnol. 2006. PMID: 16496143

Improving the production of acetyl-CoA-derived chemicals in Escherichia coli BL21(DE3) through iclR and arcA deletion.

Liu M, Ding Y, Chen H, Zhao Z, Liu H, Xian M, Zhao G. Liu M, et al. BMC Microbiol. 2017 Jan 7;17(1):10. doi: 10.1186/s12866-016-0913-2. BMC Microbiol. 2017. PMID: 28061812 Free PMC article.

Global gene expression analysis of glucose overflow metabolism in Escherichia coli and reduction of aerobic acetate formation.

Veit A, Polen T, Wendisch VF. Veit A, et al. Appl Microbiol Biotechnol. 2007 Feb;74(2):406-21. doi: 10.1007/s00253-006-0680-3. Epub 2006 Nov 25. Appl Microbiol Biotechnol. 2007. PMID: 17273855

Transcription levels of key metabolic genes are the cause for different glucose utilization pathways in E. coli B (BL21) and E. coli K (JM109).

Phue JN, Shiloach J. Phue JN, et al. J Biotechnol. 2004 Apr 8;109(1-2):21-30. doi: 10.1016/j.jbiotec.2003.10.038. J Biotechnol. 2004. PMID: 15063611

Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetase.

Valgepea K, Adamberg K, Nahku R, Lahtvee PJ, Arike L, Vilu R. Valgepea K, et al. BMC Syst Biol. 2010 Dec 1;4:166. doi: 10.1186/1752-0509-4-166. BMC Syst Biol. 2010. PMID: 21122111 Free PMC article.

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