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21878957,11979347,18089344,25886278,14560345,17043779,15115259,23827456,16169836,16820193,26137654,16865747,12180000,20594233,23473764,18586656,22890010,26040482,20589617,23954866,15935452,15002923,15889539,17596690,16472406,20031640,18234410,34145098,22425007,21770021,14714317,15871858,17214272,28094233,20979787,18068006,22470444,19083485,24797049,17725378,21367581,12186157,17522601,17243563,16418743,16303969,16489563,15103481,18328637,16953277,12855226,18333369,15259035,14679361,12454698,11601248,18951534,17215186,15216546,23095199,16828193,22902176,20805077,29395581,23612630,19694922,19954568,22375042,22664498,29926428,17685092,29796841,30245375,11523237,32549258,15840222,29407547,26142939,17002799,27545030,16936384,34167037,26559681,23818036,17284634,22595450,15192249,28252168,22846211,24491881,23382314,22519865,14603192,24519513,12083316,17449548,28598562,27783031,22084937,15831132,35346016,30904222,14626640,25449138,23936521,14656021,16379339,29572125,15681105,17551576,22034983,17914182,15719048,14997992,16522920,23314883,32645905,18979127,22926161,27759072,30255822,22354693,15952099,28689805,27187171,28440964,16197296,28526947,26031567,23346725,23698160,28981944,34134041,22360438,11918280,16244782,21947961,23172871,33693455,27065203,24193367,34855899,22188475,19742390,19598005,21854603,17028545,23024114,30098259,11683544,20221815,29695256,28514598,28463405,28004270,15856723,29532755,36530035,12964808,25948668,29716764,10381282,23610979,25985325,10782453,18386810,11343335,37121723,17333388,12877902,15051606,12801808,22219102,16391331,30120883,19342053,25395544,27756315,24656138,23885778,27755291,20696177,32064757,27905104,24943588,24131523,25557154,37111114,14628648,37101129,30052162,23110422,24449370,31630933,19094231,12707953,21338559,25634595,27973419,28472811,15181872,11375284,25601573,32888843,26689687,18716749,14580166,33219830,34409847,29461227,23287069,36308028,30451038,22217364,25456744,30999684,22147263,26667891,22983814,24223459,17024957,14633777,17238009,28261756,21543238,12540403,25591618,26421712,25854931,16379338,23161188,35822733,19768245,17654449,33612626,33013017,24846903,18074111,15970629,14656031,19178787,36876682,27086212,26797484,23586533,10996831,19625220,34836291,34907829,14746246,22610053,11708307,31651110,20216556,30074003,21475950,16445837,22833659,24018893,16570355,12512994,22648085,18309641,19204075,23887113,29117460,19560954,30837427,11592431,12450964,23741716,32199937,28397471,27864850,29600437,22116453,25168958,34717141,20399291,23385809,26837347,29062354,22824326,25048341,16763373,22647793,23787008,24247916,9359935,24572592,30114345,16599836,14657334,35832851,30781775,30405296,20818966,22069468,12720045,23285280,24448492,15765596,19372453,32325916,25998928,12694331,36806868,35463099,16612468,10446525,25536437,31277918,19093229,33724098,15189123,25173634,16723687,31446167,19450180,29722849,17726145,12482561,31362840,19219535,30278440,28854002,22237773,30592864,15354385,24656904,17885260,22611939,17024599,19294496,14752013,33486813,31440871,35750632,409812,21607713,22432562,32623588,15834031,35337625,24040787,35896125,34469084,27130656,15335152,30207526,18051992,34960114,16917400,24927906,16872232,26282718,24705833,18626236,27822905,17052662,31908954,10026668,29072168,11048629,1516378,19565010,19967264,36169739,9155210,17598967,16915776,33000156,28024829,20082058,32790014,19618311,27392858,30747607,37076800,16375580,15976531,33282308,34792727,21161416,24524080,18787277,17534029,22649899,25717482,29384828,30696543,25766590,23146986,19359001,27863359,14630804,15847753,10881913,26569075,18226574,33348139,28108882,34540786,36004588,35820507,29564841,24605633,18234134,19069163,15630149,35406106,33290257,21051057,25846884,30116976,15951337,22419558,19169966,27046515,23902779,31353838,22022143,17340683,27336853,32498429,17908667,24864108,29644956,17220211,23846402,27905385,11279635,26285484,27908565,26246496,27747917,24434266,32845472,23396527,28250422,33526724,15607115,18067447,31076249,27086080,23153734,24197804,8642469,24501746,34175159,35807880,24554143,19676146,22623744,18313674,14561573,33373019,26689889,26036286,23526309,11585023,16002792,22425167,19943541,19075497,24122186,31735046,12022240,25063980,17454207,12936915,26929921,31127676,20585951,36643223,18447992,14613740,32117640,10809271,12652108,30055159,36571739,22521537,32873057,19381504,11837987,23869894,10669187,22222235,18468429,28917233,35784143,13931577,17541043,30900398,30158810,18457979,17689540,23823922,30646578,25155498,27904562,18067446,25902009,30732165,17550314,23105344,30581350,28383037,888556,26376956,32798344,35060542,3591524,24101362,15097236,10100295,15139834,16480506,32487371,27743313,31670376,27941660,31391724,26734634,37002758,15692239,16872354,19630705,17305530,11470714,20634032,30773142,11737234,31269461,22573925,32855035,4301514,31942115,31111486,32161077,34498733,24298825,18415702,16596546,25815319,16361298,16376461,10881911,25952147,27730072,26343924,25778468,19267198,13428740,30761552,316423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Association of MTHFR and RFC1 gene polymorphism with hyperhomocysteinemia and its modulation by vitamin B12 and folic acid in an Indian population.

Sukla KK, Raman R. Sukla KK, et al. Eur J Clin Nutr. 2012 Jan;66(1):111-8. doi: 10.1038/ejcn.2011.152. Epub 2011 Aug 31. Eur J Clin Nutr. 2012. PMID: 21878957

Methylenetetrahydrofolate reductase genotype, vitamin B12, and folate influence plasma homocysteine in hemodialysis patients.

Nakamura T, Saionji K, Hiejima Y, Hirayama H, Tago K, Takano H, Tajiri M, Hayashi K, Kawabata M, Funamizu M, Makita Y, Hata A. Nakamura T, et al. Am J Kidney Dis. 2002 May;39(5):1032-9. doi: 10.1053/ajkd.2002.32779. Am J Kidney Dis. 2002. PMID: 11979347

Effect of folate, vitamin B6, and vitamin B12 intake and MTHFR C677T polymorphism on homocysteine concentrations of renal transplant recipients.

Biselli PM, Sanches de Alvarenga MP, Abbud-Filho M, Ferreira-Baptista MA, Galbiatti AL, Goto MT, Cardoso MA, Eberlin MN, Haddad R, Goloni-Bertollo EM, Pavarino-Bertelli EC. Biselli PM, et al. Transplant Proc. 2007 Dec;39(10):3163-5. doi: 10.1016/j.transproceed.2007.08.098. Transplant Proc. 2007. PMID: 18089344

Folate, vitamin B12 and Homocysteine status in the post-folic acid fortification era in different subgroups of the Brazilian population attended to at a public health care center.

Barnabé A, Aléssio AC, Bittar LF, de Moraes Mazetto B, Bicudo AM, de Paula EV, Höehr NF, Annichino-Bizzacchi JM. Barnabé A, et al. Nutr J. 2015 Feb 19;14:19. doi: 10.1186/s12937-015-0006-3. Nutr J. 2015. PMID: 25886278 Free PMC article.

The C677T mutation in methylenetetrahydrofolate reductase gene, plasma homocysteine concentration and the risk of coronary artery disease.

Kadziela J, Janas J, Dzielińska Z, Szperl M, Gaździk D, Chotkowska E, Piotrowski W, Ruzyłło W. Kadziela J, et al. Kardiol Pol. 2003 Jul;59(7):17-26; discussion 26. Kardiol Pol. 2003. PMID: 14560345

Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss.

Nadir Y, Hoffman R, Brenner B. Nadir Y, et al. Ann Hematol. 2007 Jan;86(1):35-40. doi: 10.1007/s00277-006-0194-1. Epub 2006 Oct 17. Ann Hematol. 2007. PMID: 17043779

Comparative study of response to treatment with supraphysiologic doses of B-vitamins in hyperhomocysteinemic hemodialysis patients.

Nakhoul F, Abassi Z, Plawner M, Khankin E, Ramadan R, Lanir N, Brenner B, Green J. Nakhoul F, et al. Isr Med Assoc J. 2004 Apr;6(4):213-7. Isr Med Assoc J. 2004. PMID: 15115259 Free article. Clinical Trial.

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and variations of homocysteine concentrations in patients with Behcet's disease.

Messedi M, Frigui M, Chaabouni Kh, Turki M, Neifer M, Lahiyani A, Messaouad M, Bahloul Z, Ayedi F, Jamoussi K. Messedi M, et al. Gene. 2013 Sep 15;527(1):306-10. doi: 10.1016/j.gene.2013.06.041. Epub 2013 Jul 1. Gene. 2013. PMID: 23827456

Association of B vitamins status and homocysteine levels in elderly Taiwanese.

Chen KJ, Pan WH, Yang FL, Wei IL, Shaw NS, Lin BF. Chen KJ, et al. Asia Pac J Clin Nutr. 2005;14(3):250-5. Asia Pac J Clin Nutr. 2005. PMID: 16169836 Free article.

Polymorphism C776G in the transcobalamin II gene and homocysteine, folate and vitamin B12 concentrations. Association with MTHFR C677T and A1298C and MTRR A66G polymorphisms in healthy children.

Aléssio AC, Höehr NF, Siqueira LH, Bydlowski SP, Annichino-Bizzacchi JM. Aléssio AC, et al. Thromb Res. 2007;119(5):571-7. doi: 10.1016/j.thromres.2006.05.009. Epub 2006 Jul 3. Thromb Res. 2007. PMID: 16820193

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