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Items: 1 to 20 of 96

1.

Synaptic autoregulation by metalloproteases and γ-secretase.

Restituito S, Khatri L, Ninan I, Mathews PM, Liu X, Weinberg RJ, Ziff EB.

J Neurosci. 2011 Aug 24;31(34):12083-93. doi: 10.1523/JNEUROSCI.2513-11.2011. Erratum in: J Neurosci. 2011 Sep 21;31(38):13695.

2.

Characterization of nectin processing mediated by presenilin-dependent γ-secretase.

Kim J, Chang A, Dudak A, Federoff HJ, Lim ST.

J Neurochem. 2011 Dec;119(5):945-56. doi: 10.1111/j.1471-4159.2011.07479.x. Epub 2011 Oct 20.

3.
4.

Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing.

Frykman S, Teranishi Y, Hur JY, Sandebring A, Yamamoto NG, Ancarcrona M, Nishimura T, Winblad B, Bogdanovic N, Schedin-Weiss S, Kihara T, Tjernberg LO.

Neurochem Int. 2012 Jul;61(1):108-18. doi: 10.1016/j.neuint.2012.03.016. Epub 2012 Apr 10.

PMID:
22521230
5.

Linking receptor-mediated endocytosis and cell signaling: evidence for regulated intramembrane proteolysis of megalin in proximal tubule.

Zou Z, Chung B, Nguyen T, Mentone S, Thomson B, Biemesderfer D.

J Biol Chem. 2004 Aug 13;279(33):34302-10. Epub 2004 Jun 4.

6.

The role of γ-secretase in hippocampal synaptic transmission and activity-dependent synaptic plasticity.

Chen Y, Behnisch T.

Neurosci Lett. 2013 Oct 25;554:16-21. doi: 10.1016/j.neulet.2013.08.056. Epub 2013 Sep 7.

PMID:
24016412
7.

Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production.

Hoey SE, Williams RJ, Perkinton MS.

J Neurosci. 2009 Apr 8;29(14):4442-60. doi: 10.1523/JNEUROSCI.6017-08.2009.

8.

gamma-Secretase dependent production of intracellular domains is reduced in adult compared to embryonic rat brain membranes.

Frånberg J, Karlström H, Winblad B, Tjernberg LO, Frykman S.

PLoS One. 2010 Mar 19;5(3):e9772. doi: 10.1371/journal.pone.0009772.

9.

Substrate specificity of gamma-secretase and other intramembrane proteases.

Beel AJ, Sanders CR.

Cell Mol Life Sci. 2008 May;65(9):1311-34. doi: 10.1007/s00018-008-7462-2. Review.

10.

Long-term depression-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases and presenilin/γ-secretase.

Lee H, Lee EJ, Song YS, Kim E.

Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):20130158. doi: 10.1098/rstb.2013.0158. Print 2014 Jan 5.

11.

Three-amino acid spacing of presenilin endoproteolysis suggests a general stepwise cleavage of gamma-secretase-mediated intramembrane proteolysis.

Fukumori A, Fluhrer R, Steiner H, Haass C.

J Neurosci. 2010 Jun 9;30(23):7853-62. doi: 10.1523/JNEUROSCI.1443-10.2010.

12.

Synaptic and endosomal localization of active gamma-secretase in rat brain.

Frykman S, Hur JY, Frånberg J, Aoki M, Winblad B, Nahalkova J, Behbahani H, Tjernberg LO.

PLoS One. 2010 Jan 28;5(1):e8948. doi: 10.1371/journal.pone.0008948.

13.

A novel role for {gamma}-secretase: selective regulation of spontaneous neurotransmitter release from hippocampal neurons.

Pratt KG, Zhu P, Watari H, Cook DG, Sullivan JM.

J Neurosci. 2011 Jan 19;31(3):899-906. doi: 10.1523/JNEUROSCI.4625-10.2011.

14.

Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and γ-secretase.

Hogl S, Kuhn PH, Colombo A, Lichtenthaler SF.

PLoS One. 2011;6(6):e21337. doi: 10.1371/journal.pone.0021337. Epub 2011 Jun 17.

15.

Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formation.

Inoue E, Deguchi-Tawarada M, Togawa A, Matsui C, Arita K, Katahira-Tayama S, Sato T, Yamauchi E, Oda Y, Takai Y.

J Cell Biol. 2009 May 4;185(3):551-64. doi: 10.1083/jcb.200809151.

16.

C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-β.

Andreyeva A, Nieweg K, Horstmann K, Klapper S, Müller-Schiffmann A, Korth C, Gottmann K.

Brain. 2012 Jul;135(Pt 7):2140-54. doi: 10.1093/brain/aws120. Epub 2012 May 26.

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18.

Palmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticity.

Brigidi GS, Sun Y, Beccano-Kelly D, Pitman K, Mobasser M, Borgland SL, Milnerwood AJ, Bamji SX.

Nat Neurosci. 2014 Apr;17(4):522-32. doi: 10.1038/nn.3657. Epub 2014 Feb 23.

PMID:
24562000
19.

The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

Balducci C, Mehdawy B, Mare L, Giuliani A, Lorenzini L, Sivilia S, Giardino L, Calzà L, Lanzillotta A, Sarnico I, Pizzi M, Usiello A, Viscomi AR, Ottonello S, Villetti G, Imbimbo BP, Nisticò G, Forloni G, Nisticò R.

J Alzheimers Dis. 2011;24(4):799-816. doi: 10.3233/JAD-2011-101839.

PMID:
21321397
20.

Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations.

Tampellini D, Rahman N, Gallo EF, Huang Z, Dumont M, Capetillo-Zarate E, Ma T, Zheng R, Lu B, Nanus DM, Lin MT, Gouras GK.

J Neurosci. 2009 Aug 5;29(31):9704-13. doi: 10.1523/JNEUROSCI.2292-09.2009.

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