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Results: 1 to 20 of 114

1.

Genomic-derived markers for early detection of calcineurin inhibitor immunosuppressant-mediated nephrotoxicity.

Cui Y, Huang Q, Auman JT, Knight B, Jin X, Blanchard KT, Chou J, Jayadev S, Paules RS.

Toxicol Sci. 2011 Nov;124(1):23-34. doi: 10.1093/toxsci/kfr217. Epub 2011 Aug 24.

PMID:
21865292
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Calcineurin inhibitor-free immunosuppression in pediatric renal transplantation: a viable option?

Höcker B, Tönshoff B.

Paediatr Drugs. 2011 Feb 1;13(1):49-69. doi: 10.2165/11538530-000000000-00000. Review.

PMID:
21162600
[PubMed - indexed for MEDLINE]
3.

Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models.

Liu Z, Xie J, Wu T, Truong T, Auchus RJ, Huang CL.

Hum Mol Genet. 2011 Mar 1;20(5):855-66. doi: 10.1093/hmg/ddq525. Epub 2010 Dec 2.

PMID:
21131289
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506.

Andoh TF, Burdmann EA, Fransechini N, Houghton DC, Bennett WM.

Kidney Int. 1996 Oct;50(4):1110-7.

PMID:
8887267
[PubMed - indexed for MEDLINE]
5.

Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients.

Koziolek MJ, Riess R, Geiger H, Thévenod F, Hauser IA.

Kidney Int. 2001 Jul;60(1):156-66.

PMID:
11422747
[PubMed - indexed for MEDLINE]
Free Article
6.

Kidney function and morphology after short-term combination therapy with cyclosporine A, tacrolimus and sirolimus in the rat.

Nielsen FT, Ottosen P, Starklint H, Dieperink H.

Nephrol Dial Transplant. 2003 Mar;18(3):491-6.

PMID:
12584269
[PubMed - indexed for MEDLINE]
Free Article
7.

Different renal toxicity profiles in the association of cyclosporine and tacrolimus with sirolimus in rats.

Lloberas N, Torras J, Alperovich G, Cruzado JM, Giménez-Bonafé P, Herrero-Fresneda I, Franquesa Ml, Rama I, Grinyó JM.

Nephrol Dial Transplant. 2008 Oct;23(10):3111-9. doi: 10.1093/ndt/gfn223. Epub 2008 May 9.

PMID:
18469305
[PubMed - indexed for MEDLINE]
Free Article
8.

Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat model.

Sereno J, Rodrigues-Santos P, Vala H, Rocha-Pereira P, Alves R, Fernandes J, Santos-Silva A, Carvalho E, Teixeira F, Reis F.

Int J Mol Sci. 2014 May 20;15(5):8979-97. doi: 10.3390/ijms15058979.

PMID:
24853130
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Validation of putative genomic biomarkers of nephrotoxicity in rats.

Wang EJ, Snyder RD, Fielden MR, Smith RJ, Gu YZ.

Toxicology. 2008 Apr 18;246(2-3):91-100. doi: 10.1016/j.tox.2007.12.031. Epub 2008 Jan 16.

PMID:
18289764
[PubMed - indexed for MEDLINE]
10.

Genetic and clinical determinants of early, acute calcineurin inhibitor-related nephrotoxicity: results from a kidney transplant consortium.

Jacobson PA, Schladt D, Israni A, Oetting WS, Lin YC, Leduc R, Guan W, Lamba V, Matas AJ; DeKAF Investigators.

Transplantation. 2012 Mar 27;93(6):624-31. doi: 10.1097/TP.0b013e3182461288.

PMID:
22334041
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Nature and mediators of renal lesions in kidney transplant patients given cyclosporine for more than one year.

Benigni A, Bruzzi I, Mister M, Azzollini N, Gaspari F, Perico N, Gotti E, Bertani T, Remuzzi G.

Kidney Int. 1999 Feb;55(2):674-85.

PMID:
9987092
[PubMed - indexed for MEDLINE]
Free Article
12.

Chronic cyclosporin A nephrotoxicity, P-glycoprotein overexpression, and relationships with intrarenal angiotensin II deposits.

del Moral RG, Andujar M, Ramírez C, Gómez-Morales M, Masseroli M, Aguilar M, Olmo A, Arrebola F, Guillén M, García-Chicano MJ, Nogales FF, O'Valle F.

Am J Pathol. 1997 Dec;151(6):1705-14.

PMID:
9403721
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Magnesium supplementation prevents experimental chronic cyclosporine a nephrotoxicity via renin-angiotensin system independent mechanism.

Asai T, Nakatani T, Yamanaka S, Tamada S, Kishimoto T, Tashiro K, Nakao T, Okamura M, Kim S, Iwao H, Miura K.

Transplantation. 2002 Sep 27;74(6):784-91.

PMID:
12364856
[PubMed - indexed for MEDLINE]
14.

Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity.

Young BA, Burdmann EA, Johnson RJ, Alpers CE, Giachelli CM, Eng E, Andoh T, Bennett WM, Couser WG.

Kidney Int. 1995 Aug;48(2):439-48.

PMID:
7564111
[PubMed - indexed for MEDLINE]
15.

Selective angiotensin II type 1 receptor blockade ameliorates cyclosporine nephrotoxicity.

Padi SS, Chopra K.

Pharmacol Res. 2002 May;45(5):413-20.

PMID:
12123630
[PubMed - indexed for MEDLINE]
16.

FK778 ameliorates post-transplant expression of fibrogenic growth factors and development of chronic rejection changes in rat kidney allografts.

Rintala JM, Savikko J, Rintala SE, von Willebrand E.

Nephrol Dial Transplant. 2008 Nov;23(11):3446-55. doi: 10.1093/ndt/gfn340. Epub 2008 Jun 16.

PMID:
18558624
[PubMed - indexed for MEDLINE]
Free Article
17.

FK506 alleviates proteinuria in rats with adriamycin-induced nephropathy by down-regulating TRPC6 and CaN expression.

Liu Y, Ji Z.

J Nephrol. 2012 Nov-Dec;25(6):918-25. doi: 10.5301/jn.5000192.

PMID:
22865594
[PubMed - indexed for MEDLINE]
18.

Aluminum exacerbates cyclosporin induced nephrotoxicity in rats.

Tariq M, Morais C, Sujata B, Sobki S, al Sulaiman M, al Khader A.

Ren Fail. 1999 Jan;21(1):35-48.

PMID:
10048116
[PubMed - indexed for MEDLINE]
19.

Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future.

de Mattos AM, Olyaei AJ, Bennett WM.

Am J Kidney Dis. 2000 Feb;35(2):333-46. Review.

PMID:
10676738
[PubMed - indexed for MEDLINE]
20.

Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension.

Hadchouel J, Soukaseum C, Büsst C, Zhou XO, Baudrie V, Zürrer T, Cambillau M, Elghozi JL, Lifton RP, Loffing J, Jeunemaitre X.

Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18109-14. doi: 10.1073/pnas.1006128107. Epub 2010 Oct 4.

PMID:
20921400
[PubMed - indexed for MEDLINE]
Free PMC Article
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