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Related Citations for PubMed (Select 21862452)


Increased levels of noisy splicing in cancers, but not for oncogene-derived transcripts.

Chen L, Tovar-Corona JM, Urrutia AO.

Hum Mol Genet. 2011 Nov 15;20(22):4422-9. doi: 10.1093/hmg/ddr370. Epub 2011 Aug 23.


Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay.

Zhang Z, Xin D, Wang P, Zhou L, Hu L, Kong X, Hurst LD.

BMC Biol. 2009 May 14;7:23. doi: 10.1186/1741-7007-7-23.


Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours.

Gayther SA, Barski P, Batley SJ, Li L, de Foy KA, Cohen SN, Ponder BA, Caldas C.

Oncogene. 1997 Oct 23;15(17):2119-26.


Modification of alternative splicing by antisense oligonucleotides as a potential chemotherapy for cancer and other diseases.

Mercatante DR, Sazani P, Kole R.

Curr Cancer Drug Targets. 2001 Nov;1(3):211-30. Review.


Impact of alternative initiation, splicing, and termination on the diversity of the mRNA transcripts encoded by the mouse transcriptome.

Zavolan M, Kondo S, Schonbach C, Adachi J, Hume DA, Hayashizaki Y, Gaasterland T; RIKEN GER Group; GSL Members.

Genome Res. 2003 Jun;13(6B):1290-300.


Conservation of human alternative splice events in mouse.

Thanaraj TA, Clark F, Muilu J.

Nucleic Acids Res. 2003 May 15;31(10):2544-52.


Exon-level transcriptome profiling in murine breast cancer reveals splicing changes specific to tumors with different metastatic abilities.

Bemmo A, Dias C, Rose AA, Russo C, Siegel P, Majewski J.

PLoS One. 2010 Aug 6;5(8):e11981. doi: 10.1371/journal.pone.0011981.


A global view of cancer-specific transcript variants by subtractive transcriptome-wide analysis.

He C, Zhou F, Zuo Z, Cheng H, Zhou R.

PLoS One. 2009;4(3):e4732. doi: 10.1371/journal.pone.0004732. Epub 2009 Mar 6.


Genome-wide detection of testis- and testicular cancer-specific alternative splicing.

He C, Zuo Z, Chen H, Zhang L, Zhou F, Cheng H, Zhou R.

Carcinogenesis. 2007 Dec;28(12):2484-90. Epub 2007 Aug 27.


Modification of alternative splicing pathways as a potential approach to chemotherapy.

Mercatante D, Kole R.

Pharmacol Ther. 2000 Mar;85(3):237-43. Review.


Genome-wide analysis of novel splice variants induced by topoisomerase I poisoning shows preferential occurrence in genes encoding splicing factors.

Solier S, Barb J, Zeeberg BR, Varma S, Ryan MC, Kohn KW, Weinstein JN, Munson PJ, Pommier Y.

Cancer Res. 2010 Oct 15;70(20):8055-65. doi: 10.1158/0008-5472.CAN-10-2491. Epub 2010 Sep 3.


Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells.

Chang JG, Yang DM, Chang WH, Chow LP, Chan WL, Lin HH, Huang HD, Chang YS, Hung CH, Yang WK.

PLoS One. 2011;6(6):e18643. doi: 10.1371/journal.pone.0018643. Epub 2011 Jun 9.


The adaptive significance of unproductive alternative splicing in primates.

Skandalis A, Frampton M, Seger J, Richards MH.

RNA. 2010 Oct;16(10):2014-22. doi: 10.1261/rna.2127910. Epub 2010 Aug 18.


Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer.

Hartel M, Narla G, Wente MN, Giese NA, Martignoni ME, Martignetti JA, Friess H, Friedman SL.

Eur J Cancer. 2008 Sep;44(13):1895-903. doi: 10.1016/j.ejca.2008.06.030. Epub 2008 Aug 6.


Computational analysis of splicing errors and mutations in human transcripts.

Kurmangaliyev YZ, Gelfand MS.

BMC Genomics. 2008 Jan 14;9:13. doi: 10.1186/1471-2164-9-13.


Alternative splicing in cancer: implications for biology and therapy.

Chen J, Weiss WA.

Oncogene. 2015 Jan 2;34(1):1-14. doi: 10.1038/onc.2013.570. Epub 2014 Jan 20. Review.


Synonymous mutations frequently act as driver mutations in human cancers.

Supek F, Miñana B, Valcárcel J, Gabaldón T, Lehner B.

Cell. 2014 Mar 13;156(6):1324-35. doi: 10.1016/j.cell.2014.01.051.


Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array.

Gardina PJ, Clark TA, Shimada B, Staples MK, Yang Q, Veitch J, Schweitzer A, Awad T, Sugnet C, Dee S, Davies C, Williams A, Turpaz Y.

BMC Genomics. 2006 Dec 27;7:325.

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