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Items: 1 to 20 of 130

1.

Strain-dependent CNS dissemination in guinea pigs after Mycobacterium tuberculosis aerosol challenge.

Be NA, Klinkenberg LG, Bishai WR, Karakousis PC, Jain SK.

Tuberculosis (Edinb). 2011 Sep;91(5):386-9. doi: 10.1016/j.tube.2011.07.003. Epub 2011 Aug 9.

2.

Experimental ocular tuberculosis in guinea pigs.

Rao NA, Albini TA, Kumaradas M, Pinn ML, Fraig MM, Karakousis PC.

Arch Ophthalmol. 2009 Sep;127(9):1162-6. doi: 10.1001/archophthalmol.2009.220.

3.

Disseminated disease severity as a measure of virulence of Mycobacterium tuberculosis in the guinea pig model.

Palanisamy GS, Smith EE, Shanley CA, Ordway DJ, Orme IM, Basaraba RJ.

Tuberculosis (Edinb). 2008 Jul;88(4):295-306. doi: 10.1016/j.tube.2007.12.003. Epub 2008 Mar 5.

4.

Vaccination with recombinant Mycobacterium tuberculosis PknD attenuates bacterial dissemination to the brain in guinea pigs.

Skerry C, Pokkali S, Pinn M, Be NA, Harper J, Karakousis PC, Jain SK.

PLoS One. 2013 Jun 11;8(6):e66310. doi: 10.1371/journal.pone.0066310. Print 2013.

5.

Specific bacterial genotypes of Mycobacterium tuberculosis cause extensive dissemination and brain infection in an experimental model.

Hernandez Pando R, Aguilar D, Cohen I, Guerrero M, Ribon W, Acosta P, Orozco H, Marquina B, Salinas C, Rembao D, Espitia C.

Tuberculosis (Edinb). 2010 Jul;90(4):268-77. doi: 10.1016/j.tube.2010.05.002. Epub 2010 Jun 30.

PMID:
20580613
6.

Clinical strains of Mycobacterium tuberculosis display a wide range of virulence in guinea pigs.

Palanisamy GS, DuTeau N, Eisenach KD, Cave DM, Theus SA, Kreiswirth BN, Basaraba RJ, Orme IM.

Tuberculosis (Edinb). 2009 May;89(3):203-9. doi: 10.1016/j.tube.2009.01.005. Epub 2009 Feb 28.

PMID:
19251482
7.

An assay to compare the infectivity of Mycobacterium tuberculosis isolates based on aerosol infection of guinea pigs and assessment of bacteriology.

Williams A, James BW, Bacon J, Hatch KA, Hatch GJ, Hall GA, Marsh PD.

Tuberculosis (Edinb). 2005 May;85(3):177-84. Epub 2004 Dec 25.

PMID:
15850755
8.

Examination of Mycobacterium tuberculosis sigma factor mutants using low-dose aerosol infection of guinea pigs suggests a role for SigC in pathogenesis.

Karls RK, Guarner J, McMurray DN, Birkness KA, Quinn FD.

Microbiology. 2006 Jun;152(Pt 6):1591-600.

PMID:
16735723
9.

Immunization with a mycobacterial lipid vaccine improves pulmonary pathology in the guinea pig model of tuberculosis.

Dascher CC, Hiromatsu K, Xiong X, Morehouse C, Watts G, Liu G, McMurray DN, LeClair KP, Porcelli SA, Brenner MB.

Int Immunol. 2003 Aug;15(8):915-25.

10.
11.

Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice.

Jain SK, Hernandez-Abanto SM, Cheng QJ, Singh P, Ly LH, Klinkenberg LG, Morrison NE, Converse PJ, Nuermberger E, Grosset J, McMurray DN, Karakousis PC, Lamichhane G, Bishai WR.

J Infect Dis. 2007 Jun 1;195(11):1634-42. Epub 2007 Apr 23.

12.

Increased virulence of Mycobacterium tuberculosis H37Rv overexpressing LipY in a murine model.

Singh VK, Srivastava M, Dasgupta A, Singh MP, Srivastava R, Srivastava BS.

Tuberculosis (Edinb). 2014 May;94(3):252-61. doi: 10.1016/j.tube.2014.02.001. Epub 2014 Feb 10.

PMID:
24631199
13.
14.

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis.

Williams A, Hatch GJ, Clark SO, Gooch KE, Hatch KA, Hall GA, Huygen K, Ottenhoff TH, Franken KL, Andersen P, Doherty TM, Kaufmann SH, Grode L, Seiler P, Martin C, Gicquel B, Cole ST, Brodin P, Pym AS, Dalemans W, Cohen J, Lobet Y, Goonetilleke N, McShane H, Hill A, Parish T, Smith D, Stoker NG, Lowrie DB, Källenius G, Svenson S, Pawlowski A, Blake K, Marsh PD.

Tuberculosis (Edinb). 2005 Jan-Mar;85(1-2):29-38. Epub 2005 Jan 20.

PMID:
15687025
15.

Reduced virulence of an extensively drug-resistant outbreak strain of Mycobacterium tuberculosis in a murine model.

Smith KL, Saini D, Bardarov S, Larsen M, Frothingham R, Gandhi NR, Jacobs WR Jr, Sturm AW, Lee S.

PLoS One. 2014 Apr 14;9(4):e94953. doi: 10.1371/journal.pone.0094953. eCollection 2014.

16.
17.

In vivo characteristics of Korean Beijing Mycobacterium tuberculosis strain K1 in an aerosol challenge model and in the Cornell latent tuberculosis model.

Jeon BY, Kwak J, Hahn MY, Eum SY, Yang J, Kim SC, Cho SN.

J Med Microbiol. 2012 Oct;61(Pt 10):1373-9. doi: 10.1099/jmm.0.047027-0. Epub 2012 Jul 19.

PMID:
22820694
18.

Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models.

Converse PJ, Karakousis PC, Klinkenberg LG, Kesavan AK, Ly LH, Allen SS, Grosset JH, Jain SK, Lamichhane G, Manabe YC, McMurray DN, Nuermberger EL, Bishai WR.

Infect Immun. 2009 Mar;77(3):1230-7. doi: 10.1128/IAI.01117-08. Epub 2008 Dec 22.

19.

Dry powder PA-824 aerosols for treatment of tuberculosis in guinea pigs.

Garcia-Contreras L, Sung JC, Muttil P, Padilla D, Telko M, Verberkmoes JL, Elbert KJ, Hickey AJ, Edwards DA.

Antimicrob Agents Chemother. 2010 Apr;54(4):1436-42. doi: 10.1128/AAC.01471-09. Epub 2010 Jan 19.

20.

Mycobacterium bovis BCG vaccination modulates TNF-alpha production after pulmonary challenge with virulent Mycobacterium tuberculosis in guinea pigs.

Yamamoto T, Lasco TM, Uchida K, Goto Y, Jeevan A, McFarland C, Ly L, Yamamoto S, McMurray DN.

Tuberculosis (Edinb). 2007 Mar;87(2):155-65. Epub 2007 Feb 7.

PMID:
17289434
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