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Items: 1 to 20 of 116


Serotonin and dopamine protect from hypothermia/rewarming damage through the CBS/H2S pathway.

Talaei F, Bouma HR, Van der Graaf AC, Strijkstra AM, Schmidt M, Henning RH.

PLoS One. 2011;6(7):e22568. doi: 10.1371/journal.pone.0022568. Epub 2011 Jul 27.


Induction of VMAT-1 and TPH-1 expression induces vesicular accumulation of serotonin and protects cells and tissue from cooling/rewarming injury.

Talaei F, Schmidt M, Henning RH.

PLoS One. 2012;7(1):e30400. doi: 10.1371/journal.pone.0030400. Epub 2012 Jan 12.


Ischemia-reperfusion reduces cystathionine-beta-synthase-mediated hydrogen sulfide generation in the kidney.

Xu Z, Prathapasinghe G, Wu N, Hwang SY, Siow YL, O K.

Am J Physiol Renal Physiol. 2009 Jul;297(1):F27-35. doi: 10.1152/ajprenal.00096.2009. Epub 2009 May 13.


Dopamine treatment attenuates acute kidney injury in a rat model of deep hypothermia and rewarming - the role of renal H2S-producing enzymes.

Dugbartey GJ, Talaei F, Houwertjes MC, Goris M, Epema AH, Bouma HR, Henning RH.

Eur J Pharmacol. 2015 Nov 16. pii: S0014-2999(15)30361-7. doi: 10.1016/j.ejphar.2015.11.022. [Epub ahead of print]


Cystathionine β-synthase and cystathionine γ-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation.

Sen U, Givvimani S, Abe OA, Lederer ED, Tyagi SC.

Am J Physiol Cell Physiol. 2011 Jan;300(1):C155-63. doi: 10.1152/ajpcell.00143.2010. Epub 2010 Oct 13.


Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type.

Du C, Jin M, Hong Y, Li Q, Wang XH, Xu JM, Wang F, Zhang Y, Jia J, Liu CF, Hu LF.

Biochem Biophys Res Commun. 2014 Aug 22;451(2):239-45. doi: 10.1016/j.bbrc.2014.07.107. Epub 2014 Jul 30.


Hydrogen sulfide as a cryogenic mediator of hypoxia-induced anapyrexia.

Kwiatkoski M, Soriano RN, Francescato HD, Batalhao ME, Coimbra TM, Carnio EC, Branco LG.

Neuroscience. 2012 Jan 10;201:146-56. doi: 10.1016/j.neuroscience.2011.11.030. Epub 2011 Nov 22.


Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failure.

Sen U, Basu P, Abe OA, Givvimani S, Tyagi N, Metreveli N, Shah KS, Passmore JC, Tyagi SC.

Am J Physiol Renal Physiol. 2009 Aug;297(2):F410-9. doi: 10.1152/ajprenal.00145.2009. Epub 2009 May 27.


Pharmacological activation and genetic manipulation of cystathionine beta-synthase alter circulating levels of homocysteine and hydrogen sulfide in mice.

Jensen KK, Geoghagen NS, Jin L, Holt TG, Luo Q, Malkowitz L, Ni W, Quan S, Waters MG, Zhang A, Zhou HH, Cheng K, Luo MJ.

Eur J Pharmacol. 2011 Jan 10;650(1):86-93. doi: 10.1016/j.ejphar.2010.09.080. Epub 2010 Oct 15.


Hydrogen sulfide protects against chemical hypoxia-induced injury by inhibiting ROS-activated ERK1/2 and p38MAPK signaling pathways in PC12 cells.

Lan A, Liao X, Mo L, Yang C, Yang Z, Wang X, Hu F, Chen P, Feng J, Zheng D, Xiao L.

PLoS One. 2011;6(10):e25921. doi: 10.1371/journal.pone.0025921. Epub 2011 Oct 5.


Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro.

Módis K, Coletta C, Asimakopoulou A, Szczesny B, Chao C, Papapetropoulos A, Hellmich MR, Szabo C.

Nitric Oxide. 2014 Sep 15;41:146-56. doi: 10.1016/j.niox.2014.03.001. Epub 2014 Mar 22.


Butyrate-stimulated H2S production in colon cancer cells.

Cao Q, Zhang L, Yang G, Xu C, Wang R.

Antioxid Redox Signal. 2010 May 1;12(9):1101-9. doi: 10.1089/ars.2009.2915.


Ischemia/reperfusion reduces transcription factor Sp1-mediated cystathionine beta-synthase expression in the kidney.

Wu N, Siow YL, O K.

J Biol Chem. 2010 Jun 11;285(24):18225-33. doi: 10.1074/jbc.M110.132142. Epub 2010 Apr 14.


The role of endogenous H2S formation in reversible remodeling of lung tissue during hibernation in the Syrian hamster.

Talaei F, Bouma HR, Hylkema MN, Strijkstra AM, Boerema AS, Schmidt M, Henning RH.

J Exp Biol. 2012 Aug 15;215(Pt 16):2912-9. doi: 10.1242/jeb.067363.


Hydrogen sulfide as an oxygen sensor in trout gill chemoreceptors.

Olson KR, Healy MJ, Qin Z, Skovgaard N, Vulesevic B, Duff DW, Whitfield NL, Yang G, Wang R, Perry SF.

Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R669-80. doi: 10.1152/ajpregu.00807.2007. Epub 2008 Jun 18.


Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer.

Szabo C, Coletta C, Chao C, Módis K, Szczesny B, Papapetropoulos A, Hellmich MR.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12474-9. doi: 10.1073/pnas.1306241110. Epub 2013 Jul 8.


Inhibition of cystathionine-beta-synthase activity during renal ischemia-reperfusion: role of pH and nitric oxide.

Prathapasinghe GA, Siow YL, Xu Z, O K.

Am J Physiol Renal Physiol. 2008 Oct;295(4):F912-22. doi: 10.1152/ajprenal.00040.2008. Epub 2008 Aug 13.


Activation of AMPK participates hydrogen sulfide-induced cyto-protective effect against dexamethasone in osteoblastic MC3T3-E1 cells.

Yang M, Huang Y, Chen J, Chen YL, Ma JJ, Shi PH.

Biochem Biophys Res Commun. 2014 Nov 7;454(1):42-7. doi: 10.1016/j.bbrc.2014.10.033. Epub 2014 Oct 14.


Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide.

Lee M, Schwab C, Yu S, McGeer E, McGeer PL.

Neurobiol Aging. 2009 Oct;30(10):1523-34. doi: 10.1016/j.neurobiolaging.2009.06.001. Epub 2009 Jul 23.

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