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Results: 1 to 20 of 144

1.

Bioavailability, intracellular mobilization of nickel, and HIF-1α activation in human lung epithelial cells exposed to metallic nickel and nickel oxide nanoparticles.

Pietruska JR, Liu X, Smith A, McNeil K, Weston P, Zhitkovich A, Hurt R, Kane AB.

Toxicol Sci. 2011 Nov;124(1):138-48. doi: 10.1093/toxsci/kfr206. Epub 2011 Aug 9.

PMID:
21828359
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The role of hypoxia inducible factor-1α in the increased MMP-2 and MMP-9 production by human monocytes exposed to nickel nanoparticles.

Wan R, Mo Y, Chien S, Li Y, Li Y, Tollerud DJ, Zhang Q.

Nanotoxicology. 2011 Dec;5(4):568-82. doi: 10.3109/17435390.2010.537791. Epub 2011 Mar 14.

PMID:
21401309
[PubMed - indexed for MEDLINE]
3.

Ultrafine NiO particles induce cytotoxicity in vitro by cellular uptake and subsequent Ni(II) release.

Horie M, Nishio K, Fujita K, Kato H, Nakamura A, Kinugasa S, Endoh S, Miyauchi A, Yamamoto K, Murayama H, Niki E, Iwahashi H, Yoshida Y, Nakanishi J.

Chem Res Toxicol. 2009 Aug;22(8):1415-26. doi: 10.1021/tx900171n.

PMID:
19630433
[PubMed - indexed for MEDLINE]
4.

p53 activation by Ni(II) is a HIF-1α independent response causing caspases 9/3-mediated apoptosis in human lung cells.

Wong VC, Morse JL, Zhitkovich A.

Toxicol Appl Pharmacol. 2013 Jun 15;269(3):233-9. doi: 10.1016/j.taap.2013.03.023. Epub 2013 Apr 6.

PMID:
23566959
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-inducible factor-1 alpha (HIF-1alpha) and HIF-regulated genes.

Li Q, Chen H, Huang X, Costa M.

Toxicol Appl Pharmacol. 2006 Jun 15;213(3):245-55. Epub 2006 Jan 4.

PMID:
16386771
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Uptake, p53 pathway activation, and cytotoxic responses for Co(II) and Ni(II) in human lung cells: implications for carcinogenicity.

Green SE, Luczak MW, Morse JL, DeLoughery Z, Zhitkovich A.

Toxicol Sci. 2013 Dec;136(2):467-77. doi: 10.1093/toxsci/kft214. Epub 2013 Sep 25.

PMID:
24068677
[PubMed - indexed for MEDLINE]
7.

Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors.

Salnikow K, An WG, Melillo G, Blagosklonny MV, Costa M.

Carcinogenesis. 1999 Sep;20(9):1819-23.

PMID:
10469629
[PubMed - indexed for MEDLINE]
Free Article
8.

Comparative pulmonary toxicity of inhaled nickel nanoparticles; role of deposited dose and solubility.

Kang GS, Gillespie PA, Gunnison A, Rengifo H, Koberstein J, Chen LC.

Inhal Toxicol. 2011 Feb;23(2):95-103. doi: 10.3109/08958378.2010.543440. Epub 2011 Jan 24.

PMID:
21261442
[PubMed - indexed for MEDLINE]
9.

Comparison of acute oxidative stress on rat lung induced by nano and fine-scale, soluble and insoluble metal oxide particles: NiO and TiO2.

Horie M, Fukui H, Endoh S, Maru J, Miyauchi A, Shichiri M, Fujita K, Niki E, Hagihara Y, Yoshida Y, Morimoto Y, Iwahashi H.

Inhal Toxicol. 2012 Jun;24(7):391-400. doi: 10.3109/08958378.2012.682321.

PMID:
22642288
[PubMed - indexed for MEDLINE]
10.

The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis.

Salnikow K, Davidson T, Zhang Q, Chen LC, Su W, Costa M.

Cancer Res. 2003 Jul 1;63(13):3524-30.

PMID:
12839937
[PubMed - indexed for MEDLINE]
Free Article
11.

Co-exposure to nickel and cobalt chloride enhances cytotoxicity and oxidative stress in human lung epithelial cells.

Patel E, Lynch C, Ruff V, Reynolds M.

Toxicol Appl Pharmacol. 2012 Feb 1;258(3):367-75. doi: 10.1016/j.taap.2011.11.019. Epub 2011 Dec 8.

PMID:
22172632
[PubMed - indexed for MEDLINE]
12.
13.

Nickel ENMs activate HIF-1α.

Kessler R.

Environ Health Perspect. 2011 Dec;119(12):A512. doi: 10.1289/ehp.119-a512a. No abstract available.

PMID:
22133446
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The role of ascorbate in the modulation of HIF-1alpha protein and HIF-dependent transcription by chromium(VI) and nickel(II).

Kaczmarek M, Timofeeva OA, Karaczyn A, Malyguine A, Kasprzak KS, Salnikow K.

Free Radic Biol Med. 2007 Apr 15;42(8):1246-57. Epub 2007 Jan 19.

PMID:
17382205
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

In vitro evaluation of the toxicity induced by nickel soluble and particulate forms in human airway epithelial cells.

Forti E, Salovaara S, Cetin Y, Bulgheroni A, Tessadri R, Jennings P, Pfaller W, Prieto P.

Toxicol In Vitro. 2011 Mar;25(2):454-61. doi: 10.1016/j.tiv.2010.11.013. Epub 2010 Nov 25.

PMID:
21111804
[PubMed - indexed for MEDLINE]
16.

Toxic response of nickel nanoparticles in human lung epithelial A549 cells.

Ahamed M.

Toxicol In Vitro. 2011 Jun;25(4):930-6. doi: 10.1016/j.tiv.2011.02.015. Epub 2011 Mar 3.

PMID:
21376802
[PubMed - indexed for MEDLINE]
17.

Nickel and the microbial toxin, MALP-2, stimulate proangiogenic mediators from human lung fibroblasts via a HIF-1alpha and COX-2-mediated pathway.

Brant KA, Fabisiak JP.

Toxicol Sci. 2009 Jan;107(1):227-37. doi: 10.1093/toxsci/kfn208. Epub 2008 Oct 1.

PMID:
18832182
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Oxidative DNA damage in cultured cells and rat lungs by carcinogenic nickel compounds.

Kawanishi S, Inoue S, Oikawa S, Yamashita N, Toyokuni S, Kawanishi M, Nishino K.

Free Radic Biol Med. 2001 Jul 1;31(1):108-16.

PMID:
11425496
[PubMed - indexed for MEDLINE]
19.

Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.

Salnikow K, Donald SP, Bruick RK, Zhitkovich A, Phang JM, Kasprzak KS.

J Biol Chem. 2004 Sep 24;279(39):40337-44. Epub 2004 Jul 22.

PMID:
15271983
[PubMed - indexed for MEDLINE]
Free Article
20.

Effect of soluble and particulate nickel compounds on the formation and repair of stable benzo[a]pyrene DNA adducts in human lung cells.

Schwerdtle T, Seidel A, Hartwig A.

Carcinogenesis. 2002 Jan;23(1):47-53.

PMID:
11756222
[PubMed - indexed for MEDLINE]
Free Article

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