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Items: 1 to 20 of 199

1.

GATA6 activates Wnt signaling in pancreatic cancer by negatively regulating the Wnt antagonist Dickkopf-1.

Zhong Y, Wang Z, Fu B, Pan F, Yachida S, Dhara M, Albesiano E, Li L, Naito Y, Vilardell F, Cummings C, Martinelli P, Li A, Yonescu R, Ma Q, Griffin CA, Real FX, Iacobuzio-Donahue CA.

PLoS One. 2011;6(7):e22129. doi: 10.1371/journal.pone.0022129. Epub 2011 Jul 19.

2.

Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.

Hermann PC, Sancho P, Cañamero M, Martinelli P, Madriles F, Michl P, Gress T, de Pascual R, Gandia L, Guerra C, Barbacid M, Wagner M, Vieira CR, Aicher A, Real FX, Sainz B Jr, Heeschen C.

Gastroenterology. 2014 Nov;147(5):1119-33.e4. doi: 10.1053/j.gastro.2014.08.002. Epub 2014 Aug 12.

PMID:
25127677
3.

Overexpression of fibroblast growth factor receptor 4 in high-grade pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma.

Motoda N, Matsuda Y, Onda M, Ishiwata T, Uchida E, Naito Z.

Int J Oncol. 2011 Jan;38(1):133-43.

PMID:
21109934
4.

Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma.

Kocemba KA, Groen RW, van Andel H, Kersten MJ, Mahtouk K, Spaargaren M, Pals ST.

PLoS One. 2012;7(2):e30359. doi: 10.1371/journal.pone.0030359. Epub 2012 Feb 17.

5.

Dickkopf-1 is overexpressed in human pancreatic ductal adenocarcinoma cells and is involved in invasive growth.

Takahashi N, Fukushima T, Yorita K, Tanaka H, Chijiiwa K, Kataoka H.

Int J Cancer. 2010 Apr 1;126(7):1611-20. doi: 10.1002/ijc.24865.

6.

Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/β-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected].

Huang Z, Li S, Song W, Li X, Li Q, Zhang Z, Han Y, Zhang X, Miao S, Du R, Wang L.

PLoS One. 2013 Jul 26;8(7):e70077. doi: 10.1371/journal.pone.0070077. Print 2013. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/d090733e-1f34-43c5-a06a-255456946303.

7.

Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling.

Nones K, Waddell N, Song S, Patch AM, Miller D, Johns A, Wu J, Kassahn KS, Wood D, Bailey P, Fink L, Manning S, Christ AN, Nourse C, Kazakoff S, Taylor D, Leonard C, Chang DK, Jones MD, Thomas M, Watson C, Pinese M, Cowley M, Rooman I, Pajic M; APGI, Butturini G, Malpaga A, Corbo V, Crippa S, Falconi M, Zamboni G, Castelli P, Lawlor RT, Gill AJ, Scarpa A, Pearson JV, Biankin AV, Grimmond SM.

Int J Cancer. 2014 Sep 1;135(5):1110-8. doi: 10.1002/ijc.28765. Epub 2014 May 9.

8.

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma.

Qiang YW, Barlogie B, Rudikoff S, Shaughnessy JD Jr.

Bone. 2008 Apr;42(4):669-80. doi: 10.1016/j.bone.2007.12.006. Epub 2007 Dec 27.

PMID:
18294945
9.

Dickkopf-1 is involved in invasive growth of esophageal cancer cells.

Li S, Qin X, Liu B, Sun L, Zhang X, Li Z, Shan B, You J, Zhou Q.

J Mol Histol. 2011 Dec;42(6):491-8. doi: 10.1007/s10735-011-9347-1. Epub 2011 Sep 10.

PMID:
21909757
10.

A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progression.

Wang WY, Hsu CC, Wang TY, Li CR, Hou YC, Chu JM, Lee CT, Liu MS, Su JJ, Jian KY, Huang SS, Jiang SS, Shan YS, Lin PW, Shen YY, Lee MT, Chan TS, Chang CC, Chen CH, Chang IS, Lee YL, Chen LT, Tsai KK.

Gastroenterology. 2013 Nov;145(5):1110-20. doi: 10.1053/j.gastro.2013.07.040. Epub 2013 Jul 27.

PMID:
23896173
11.

Exploring the Wnt pathway-associated LncRNAs and genes involved in pancreatic carcinogenesis driven by Tp53 mutation.

Wang Q, Jiang H, Ping C, Shen R, Liu T, Li J, Qian Y, Tang Y, Cheng S, Yao W, Wang L.

Pharm Res. 2015 Mar;32(3):793-805. doi: 10.1007/s11095-013-1269-z. Epub 2014 Jan 28.

PMID:
24469904
12.

GATA6 and FOXA2 regulate Wnt6 expression during extraembryonic endoderm formation.

Hwang JT, Kelly GM.

Stem Cells Dev. 2012 Nov 20;21(17):3220-32. doi: 10.1089/scd.2011.0492. Epub 2012 Jun 25.

PMID:
22607194
13.

Genistein affects histone modifications on Dickkopf-related protein 1 (DKK1) gene in SW480 human colon cancer cell line.

Wang H, Li Q, Chen H.

PLoS One. 2012;7(7):e40955. doi: 10.1371/journal.pone.0040955. Epub 2012 Jul 18.

14.

Galectin-3 accelerates the progression of oral tongue squamous cell carcinoma via a Wnt/β-catenin-dependent pathway.

Wang LP, Chen SW, Zhuang SM, Li H, Song M.

Pathol Oncol Res. 2013 Jul;19(3):461-74. doi: 10.1007/s12253-013-9603-7. Epub 2013 Mar 22.

PMID:
23519607
15.

Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer.

Kwei KA, Bashyam MD, Kao J, Ratheesh R, Reddy EC, Kim YH, Montgomery K, Giacomini CP, Choi YL, Chatterjee S, Karikari CA, Salari K, Wang P, Hernandez-Boussard T, Swarnalata G, van de Rijn M, Maitra A, Pollack JR.

PLoS Genet. 2008 May 23;4(5):e1000081. doi: 10.1371/journal.pgen.1000081.

16.

Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation.

Koppen A, Ait-Aissa R, Hopman S, Koster J, Haneveld F, Versteeg R, Valentijn LJ.

Cancer Lett. 2007 Oct 28;256(2):218-28. Epub 2007 Jul 23.

PMID:
17643814
17.

Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression.

Froeling FE, Feig C, Chelala C, Dobson R, Mein CE, Tuveson DA, Clevers H, Hart IR, Kocher HM.

Gastroenterology. 2011 Oct;141(4):1486-97, 1497.e1-14. doi: 10.1053/j.gastro.2011.06.047. Epub 2011 Jun 24.

PMID:
21704588
18.

Frequent genomic copy number gain and overexpression of GATA-6 in pancreatic carcinoma.

Fu B, Luo M, Lakkur S, Lucito R, Iacobuzio-Donahue CA.

Cancer Biol Ther. 2008 Oct;7(10):1593-601. Epub 2008 Oct 7.

PMID:
18769116
19.

Insig2 is overexpressed in pancreatic cancer and its expression is induced by hypoxia.

Kayashima T, Nakata K, Ohuchida K, Ueda J, Shirahane K, Fujita H, Cui L, Mizumoto K, Tanaka M.

Cancer Sci. 2011 Jun;102(6):1137-43. doi: 10.1111/j.1349-7006.2011.01936.x. Epub 2011 Apr 27.

20.

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma.

Arensman MD, Kovochich AN, Kulikauskas RM, Lay AR, Yang PT, Li X, Donahue T, Major MB, Moon RT, Chien AJ, Dawson DW.

Oncogene. 2014 Feb 13;33(7):899-908. doi: 10.1038/onc.2013.23. Epub 2013 Feb 18.

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