Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 108

1.

The grand challenges in cardiovascular drug discovery and development.

Ohlstein EH.

Front Pharmacol. 2010 Sep 23;1:125. doi: 10.3389/fphar.2010.00125. eCollection 2010. No abstract available.

PMID:
21811459
[PubMed]
Free PMC Article
2.

Grand challenges for psychiatric drug discovery: a perspective.

Brady LS, Giffin RB, Woodcock J, Cassell GH, Holmes EW.

Neuropsychopharmacology. 2008 Aug;33(9):2047. doi: 10.1038/npp.2008.54. No abstract available.

PMID:
18626470
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Grand Challenges Canada: inappropriate emphasis and missed opportunities in global health research?

Larson CP, Haddad S, Birn AE, Cole DC, Labonte R, Roberts JH, Schrecker T, Sellen D, Zakus D.

Can J Public Health. 2011 Mar-Apr;102(2):149-51.

PMID:
21608389
[PubMed - indexed for MEDLINE]
4.

Lost in translation: five grand challenges for proteomic biomarker discovery.

Arab S, Liu PP, Emili A.

Expert Opin Med Diagn. 2007 Nov;1(3):325-36. doi: 10.1517/17530059.1.3.325.

PMID:
23489353
[PubMed]
5.

Conference report: summary of the 2010 Applied Pharmaceutical Analysis Conference.

Unger SE.

Bioanalysis. 2011 Jan;3(1):11-5. doi: 10.4155/bio.10.183.

PMID:
21175361
[PubMed - indexed for MEDLINE]
Free Article
6.

The zebrafish as a novel tool for cardiovascular drug discovery.

Rocke J, Lees J, Packham I, Chico T.

Recent Pat Cardiovasc Drug Discov. 2009 Jan;4(1):1-5. Review.

PMID:
19149699
[PubMed - indexed for MEDLINE]
7.
8.

Anticancer drug development: the grand challenges.

Hait WN.

Nat Rev Drug Discov. 2010 Apr;9(4):253-4. doi: 10.1038/nrd3144.

PMID:
20369394
[PubMed - indexed for MEDLINE]
9.

The future of molecular dynamics simulations in drug discovery.

Borhani DW, Shaw DE.

J Comput Aided Mol Des. 2012 Jan;26(1):15-26. doi: 10.1007/s10822-011-9517-y. Epub 2011 Dec 20.

PMID:
22183577
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Cardiovascular drug discovery in the academic setting: building infrastructure, harnessing strengths, and seeking synergies.

Gardell SJ, Roth GP, Kelly DP.

J Cardiovasc Transl Res. 2010 Oct;3(5):431-7. doi: 10.1007/s12265-010-9204-8. Epub 2010 Jul 13.

PMID:
20625868
[PubMed - indexed for MEDLINE]
11.

Analysis of the mass media coverage of the Gates Foundation grand challenges in global health initiative.

Verma G.

J Med Ethics. 2009 Mar;35(3):163-7. doi: 10.1136/jme.2008.025353.

PMID:
19251966
[PubMed - indexed for MEDLINE]
12.

Grand challenges in dental informatics.

Sittig DF, Kirshner M, Maupomé G.

Adv Dent Res. 2003 Dec;17:16-9.

PMID:
15126200
[PubMed - indexed for MEDLINE]
13.

The discovery of nongenotoxic activators of p53: building on a cell-based high-throughput screen.

McCarthy AR, Hollick JJ, Westwood NJ.

Semin Cancer Biol. 2010 Feb;20(1):40-5. doi: 10.1016/j.semcancer.2010.02.007. Epub 2010 Mar 4. Review.

PMID:
20206696
[PubMed - indexed for MEDLINE]
14.

The rationality for using prodrug approach in drug discovery programs for new xenobiotics: opportunities and challenges.

Srinivas NR.

Eur J Drug Metab Pharmacokinet. 2011 Jun;36(2):49-59. doi: 10.1007/s13318-011-0035-z. Epub 2011 Mar 15. Review.

PMID:
21404122
[PubMed - indexed for MEDLINE]
15.

Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities.

Uzuner H, Bauer R, Fan TP, Guo DA, Dias A, El-Nezami H, Efferth T, Williamson EM, Heinrich M, Robinson N, Hylands PJ, Hendry BM, Cheng YC, Xu Q.

J Ethnopharmacol. 2012 Apr 10;140(3):458-68. doi: 10.1016/j.jep.2012.02.028. Epub 2012 Feb 23.

PMID:
22387462
[PubMed - indexed for MEDLINE]
Free Article
16.

Novel stem cell-based drug discovery platforms for cardiovascular disease.

Adams WJ, García-Cardeña G.

J Biomol Screen. 2012 Oct;17(9):1117-27. Epub 2012 Aug 1. Review.

PMID:
22853930
[PubMed - indexed for MEDLINE]
17.

Pharmacophore modeling and applications in drug discovery: challenges and recent advances.

Yang SY.

Drug Discov Today. 2010 Jun;15(11-12):444-50. doi: 10.1016/j.drudis.2010.03.013. Epub 2010 Apr 1. Review.

PMID:
20362693
[PubMed - indexed for MEDLINE]
18.

The ten grand challenges of synthetic life.

Porcar M, Danchin A, de Lorenzo V, Dos Santos VA, Krasnogor N, Rasmussen S, Moya A.

Syst Synth Biol. 2011 Jun;5(1-2):1-9. doi: 10.1007/s11693-011-9084-5. Epub 2011 Aug 5.

PMID:
21949672
[PubMed]
Free PMC Article
19.

Discovery of small molecule cancer drugs: successes, challenges and opportunities.

Hoelder S, Clarke PA, Workman P.

Mol Oncol. 2012 Apr;6(2):155-76. doi: 10.1016/j.molonc.2012.02.004. Epub 2012 Mar 3. Review.

PMID:
22440008
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Opportunities and challenges in the discovery of new central nervous system drugs.

Krause JE, Chenard BL.

Ann N Y Acad Sci. 2008 Nov;1144:243-50. doi: 10.1196/annals.1418.024.

PMID:
19076381
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk