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Results: 1 to 20 of 133

1.

Comparative genomics of Esx genes from clinical isolates of Mycobacterium tuberculosis provides evidence for gene conversion and epitope variation.

Uplekar S, Heym B, Friocourt V, Rougemont J, Cole ST.

Infect Immun. 2011 Oct;79(10):4042-9. doi: 10.1128/IAI.05344-11. Epub 2011 Aug 1.

PMID:
21807910
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential.

Sayes F, Sun L, Di Luca M, Simeone R, Degaiffier N, Fiette L, Esin S, Brosch R, Bottai D, Leclerc C, Majlessi L.

Cell Host Microbe. 2012 Apr 19;11(4):352-63. doi: 10.1016/j.chom.2012.03.003.

PMID:
22520463
[PubMed - indexed for MEDLINE]
Free Article
3.
4.

Variation of the Mycobacterium tuberculosis PE_PGRS 33 gene among clinical isolates.

Talarico S, Cave MD, Marrs CF, Foxman B, Zhang L, Yang Z.

J Clin Microbiol. 2005 Oct;43(10):4954-60.

PMID:
16207947
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Solution structure of the Mycobacterium tuberculosis EsxG·EsxH complex: functional implications and comparisons with other M. tuberculosis Esx family complexes.

Ilghari D, Lightbody KL, Veverka V, Waters LC, Muskett FW, Renshaw PS, Carr MD.

J Biol Chem. 2011 Aug 26;286(34):29993-30002. doi: 10.1074/jbc.M111.248732. Epub 2011 Jul 5.

PMID:
21730061
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions.

Gey van Pittius NC, Sampson SL, Lee H, Kim Y, van Helden PD, Warren RM.

BMC Evol Biol. 2006 Nov 15;6:95.

PMID:
17105670
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Evidence for a rapid rate of molecular evolution at the hypervariable and immunogenic Mycobacterium tuberculosis PPE38 gene region.

McEvoy CR, van Helden PD, Warren RM, Gey van Pittius NC.

BMC Evol Biol. 2009 Sep 21;9:237. doi: 10.1186/1471-2148-9-237.

PMID:
19769792
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.

Fleischmann RD, Alland D, Eisen JA, Carpenter L, White O, Peterson J, DeBoy R, Dodson R, Gwinn M, Haft D, Hickey E, Kolonay JF, Nelson WC, Umayam LA, Ermolaeva M, Salzberg SL, Delcher A, Utterback T, Weidman J, Khouri H, Gill J, Mikula A, Bishai W, Jacobs Jr WR Jr, Venter JC, Fraser CM.

J Bacteriol. 2002 Oct;184(19):5479-90.

PMID:
12218036
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The ESX-5 associated eccB-EccC locus is essential for Mycobacterium tuberculosis viability.

Di Luca M, Bottai D, Batoni G, Orgeur M, Aulicino A, Counoupas C, Campa M, Brosch R, Esin S.

PLoS One. 2012;7(12):e52059. doi: 10.1371/journal.pone.0052059. Epub 2012 Dec 17.

PMID:
23284869
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Sequence diversity in the pe_pgrs genes of Mycobacterium tuberculosis is independent of human T cell recognition.

Copin R, Coscollá M, Seiffert SN, Bothamley G, Sutherland J, Mbayo G, Gagneux S, Ernst JD.

MBio. 2014 Jan 14;5(1):e00960-13. doi: 10.1128/mBio.00960-13.

PMID:
24425732
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The crystal structure of the Mycobacterium tuberculosis Rv3019c-Rv3020c ESX complex reveals a domain-swapped heterotetramer.

Arbing MA, Kaufmann M, Phan T, Chan S, Cascio D, Eisenberg D.

Protein Sci. 2010 Sep;19(9):1692-703. doi: 10.1002/pro.451.

PMID:
20629176
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mutually dependent secretion of proteins required for mycobacterial virulence.

Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10676-81. Epub 2005 Jul 19.

PMID:
16030141
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation.

Bottai D, Di Luca M, Majlessi L, Frigui W, Simeone R, Sayes F, Bitter W, Brennan MJ, Leclerc C, Batoni G, Campa M, Brosch R, Esin S.

Mol Microbiol. 2012 Mar;83(6):1195-209. doi: 10.1111/j.1365-2958.2012.08001.x. Epub 2012 Feb 20.

PMID:
22340629
[PubMed - indexed for MEDLINE]
14.

[Frontier of mycobacterium research--host vs. mycobacterium].

Okada M, Shirakawa T.

Kekkaku. 2005 Sep;80(9):613-29. Japanese.

PMID:
16245793
[PubMed - indexed for MEDLINE]
15.

Conservation of structure and protein-protein interactions mediated by the secreted mycobacterial proteins EsxA, EsxB, and EspA.

Callahan B, Nguyen K, Collins A, Valdes K, Caplow M, Crossman DK, Steyn AJ, Eisele L, Derbyshire KM.

J Bacteriol. 2010 Jan;192(1):326-35. doi: 10.1128/JB.01032-09. Epub .

PMID:
19854905
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Genetic diversity of antigens Rv2945c and Rv0309 in Mycobacterium tuberculosis strains may reflect ongoing immune evasion.

Jiang Y, Dou X, Zhang W, Liu H, Zhao X, Wang H, Lian L, Yu Q, Zhang J, Li G, Chen C, Wan K.

FEMS Microbiol Lett. 2013 Oct;347(1):77-82. doi: 10.1111/1574-6968.12222. Epub 2013 Aug 23.

PMID:
23889607
[PubMed - indexed for MEDLINE]
17.

Comparative evaluation of low-molecular-mass proteins from Mycobacterium tuberculosis identifies members of the ESAT-6 family as immunodominant T-cell antigens.

Skjøt RL, Oettinger T, Rosenkrands I, Ravn P, Brock I, Jacobsen S, Andersen P.

Infect Immun. 2000 Jan;68(1):214-20.

PMID:
10603390
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mycobacterium tuberculosis PE_PGRS16 and PE_PGRS26 genetic polymorphism among clinical isolates.

Talarico S, Zhang L, Marrs CF, Foxman B, Cave MD, Brennan MJ, Yang Z.

Tuberculosis (Edinb). 2008 Jul;88(4):283-94. doi: 10.1016/j.tube.2008.01.001. Epub 2008 Mar 4.

PMID:
18313360
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A new high-throughput AFLP approach for identification of new genetic polymorphism in the genome of the clonal microorganism Mycobacterium tuberculosis.

van den Braak N, Simons G, Gorkink R, Reijans M, Eadie K, Kremers K, van Soolingen D, Savelkoul P, Verbrugh H, van Belkum A.

J Microbiol Methods. 2004 Jan;56(1):49-62.

PMID:
14706750
[PubMed - indexed for MEDLINE]
20.

Analysis of genetic polymorphisms affecting the four phospholipase C (plc) genes in Mycobacterium tuberculosis complex clinical isolates.

Viana-Niero C, de Haas PE, van Soolingen D, Leão SC.

Microbiology. 2004 Apr;150(Pt 4):967-78.

PMID:
15073306
[PubMed - indexed for MEDLINE]
Free Article

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