Similar articles for PMID: 21802945

Year	Number of Results
1982	1
1989	1
1991	1
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1997	1
2000	2
2002	2
2003	3
2004	2
2005	3
2006	5
2007	2
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2009	3
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2012	4
2013	10
2014	5
2015	7
2016	3
2017	7
2018	7
2019	6
2020	8
2021	3
2022	2
2023	2
2024	0

1

Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy.

Taldone T, Gomes-DaGama EM, Zong H, Sen S, Alpaugh ML, Zatorska D, Alonso-Sabadell R, Guzman ML, Chiosis G. Taldone T, et al. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5347-52. doi: 10.1016/j.bmcl.2011.07.026. Epub 2011 Jul 14. Bioorg Med Chem Lett. 2011. PMID: 21802945 Free PMC article.

2

The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1.

Usmani SZ, Bona RD, Chiosis G, Li Z. Usmani SZ, et al. J Hematol Oncol. 2010 Oct 26;3:40. doi: 10.1186/1756-8722-3-40. J Hematol Oncol. 2010. PMID: 20977755 Free PMC article.

3

Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2.

Gallerne C, Prola A, Lemaire C. Gallerne C, et al. Biochim Biophys Acta. 2013 Jun;1833(6):1356-66. doi: 10.1016/j.bbamcr.2013.02.014. Epub 2013 Feb 26. Biochim Biophys Acta. 2013. PMID: 23485394 Free article.

4

Radiosynthesis of the iodine-124 labeled Hsp90 inhibitor PU-H71.

Taldone T, Zatorska D, Ochiana SO, Smith-Jones P, Koziorowski J, Dunphy MP, Zanzonico P, Bolaender A, Lewis JS, Larson SM, Chiosis G, Pillarsetty NV. Taldone T, et al. J Labelled Comp Radiopharm. 2016 Mar;59(3):129-32. doi: 10.1002/jlcr.3369. Epub 2016 Jan 25. J Labelled Comp Radiopharm. 2016. PMID: 26806023 Free PMC article.

5

Radiosensitization of human lung cancer cells by the novel purine-scaffold Hsp90 inhibitor, PU-H71.

Segawa T, Fujii Y, Tanaka A, Bando S, Okayasu R, Ohnishi K, Kubota N. Segawa T, et al. Int J Mol Med. 2014 Mar;33(3):559-64. doi: 10.3892/ijmm.2013.1594. Epub 2013 Dec 19. Int J Mol Med. 2014. PMID: 24366006

6

The purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining.

Lee Y, Li HK, Masaoka A, Sunada S, Hirakawa H, Fujimori A, Nickoloff JA, Okayasu R. Lee Y, et al. Radiother Oncol. 2016 Oct;121(1):162-168. doi: 10.1016/j.radonc.2016.08.029. Epub 2016 Sep 22. Radiother Oncol. 2016. PMID: 27666928 Free PMC article.

7

Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies.

Nayar U, Lu P, Goldstein RL, Vider J, Ballon G, Rodina A, Taldone T, Erdjument-Bromage H, Chomet M, Blasberg R, Melnick A, Cerchietti L, Chiosis G, Wang YL, Cesarman E. Nayar U, et al. Blood. 2013 Oct 17;122(16):2837-47. doi: 10.1182/blood-2013-01-479972. Epub 2013 Aug 13. Blood. 2013. PMID: 23943653 Free PMC article.

8

Synthesis of a red-shifted fluorescence polarization probe for Hsp90.

Moulick K, Clement CC, Aguirre J, Kim J, Kang Y, Felts S, Chiosis G. Moulick K, et al. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4515-8. doi: 10.1016/j.bmcl.2006.06.025. Epub 2006 Jun 22. Bioorg Med Chem Lett. 2006. PMID: 16797988

9

PU-H71, a novel Hsp90 inhibitor, as a potential cancer-specific sensitizer to carbon-ion beam therapy.

Li HK, Matsumoto Y, Furusawa Y, Kamada T. Li HK, et al. J Radiat Res. 2016 Sep;57(5):572-575. doi: 10.1093/jrr/rrw054. Epub 2016 May 29. J Radiat Res. 2016. PMID: 27242340 Free PMC article.

10

Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models.

Caldas-Lopes E, Cerchietti L, Ahn JH, Clement CC, Robles AI, Rodina A, Moulick K, Taldone T, Gozman A, Guo Y, Wu N, de Stanchina E, White J, Gross SS, Ma Y, Varticovski L, Melnick A, Chiosis G. Caldas-Lopes E, et al. Proc Natl Acad Sci U S A. 2009 May 19;106(20):8368-73. doi: 10.1073/pnas.0903392106. Epub 2009 May 5. Proc Natl Acad Sci U S A. 2009. PMID: 19416831 Free PMC article.

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