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Results: 1 to 20 of 137

Similar articles for PubMed (Select 21789790)

1.

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis.

Bluemlein K, Grüning NM, Feichtinger RG, Lehrach H, Kofler B, Ralser M.

Oncotarget. 2011 May;2(5):393-400.

2.

Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.

Chiavarina B, Whitaker-Menezes D, Martinez-Outschoorn UE, Witkiewicz AK, Birbe R, Howell A, Pestell RG, Smith J, Daniel R, Sotgia F, Lisanti MP.

Cancer Biol Ther. 2011 Dec 15;12(12):1101-13. doi: 10.4161/cbt.12.12.18703. Epub 2011 Dec 15.

3.

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer.

David CJ, Chen M, Assanah M, Canoll P, Manley JL.

Nature. 2010 Jan 21;463(7279):364-8. doi: 10.1038/nature08697. Epub 2009 Dec 13.

4.

Isoform switch of pyruvate kinase M1 indeed occurs but not to pyruvate kinase M2 in human tumorigenesis.

Zhan C, Yan L, Wang L, Ma J, Jiang W, Zhang Y, Shi Y, Wang Q.

PLoS One. 2015 Mar 4;10(3):e0118663. doi: 10.1371/journal.pone.0118663. eCollection 2015.

5.

Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA.

Chen M, Zhang J, Manley JL.

Cancer Res. 2010 Nov 15;70(22):8977-80. doi: 10.1158/0008-5472.CAN-10-2513. Epub 2010 Oct 26. Review.

6.

Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma.

Mukherjee J, Phillips JJ, Zheng S, Wiencke J, Ronen SM, Pieper RO.

PLoS One. 2013;8(2):e57610. doi: 10.1371/journal.pone.0057610. Epub 2013 Feb 25.

7.

Nuclear PKM2 regulates the Warburg effect.

Yang W, Lu Z.

Cell Cycle. 2013 Oct 1;12(19):3154-8. doi: 10.4161/cc.26182. Epub 2013 Aug 26.

8.

1-(sulfonyl)-5-(arylsulfonyl)indoline as activators of the tumor cell specific M2 isoform of pyruvate kinase.

Yacovan A, Ozeri R, Kehat T, Mirilashvili S, Sherman D, Aizikovich A, Shitrit A, Ben-Zeev E, Schutz N, Bohana-Kashtan O, Konson A, Behar V, Becker OM.

Bioorg Med Chem Lett. 2012 Oct 15;22(20):6460-8. doi: 10.1016/j.bmcl.2012.08.054. Epub 2012 Aug 23.

PMID:
22963766
9.

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers.

Desai S, Ding M, Wang B, Lu Z, Zhao Q, Shaw K, Yung WK, Weinstein JN, Tan M, Yao J.

Oncotarget. 2014 Sep 30;5(18):8202-10.

10.

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.

Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R, Fleming MD, Schreiber SL, Cantley LC.

Nature. 2008 Mar 13;452(7184):230-3. doi: 10.1038/nature06734.

PMID:
18337823
11.

Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells.

Wittwer JA, Robbins D, Wang F, Codarin S, Shen X, Kevil CG, Huang TT, Van Remmen H, Richardson A, Zhao Y.

Cancer Prev Res (Phila). 2011 Sep;4(9):1476-84. doi: 10.1158/1940-6207.CAPR-11-0028. Epub 2011 Jun 14.

12.

miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect.

Sun Y, Zhao X, Zhou Y, Hu Y.

Oncol Rep. 2012 Oct;28(4):1346-52. doi: 10.3892/or.2012.1958. Epub 2012 Aug 8.

PMID:
22895557
13.

Pyruvate kinase M2 facilitates colon cancer cell migration via the modulation of STAT3 signalling.

Yang P, Li Z, Fu R, Wu H, Li Z.

Cell Signal. 2014 Sep;26(9):1853-62. doi: 10.1016/j.cellsig.2014.03.020. Epub 2014 Mar 29.

PMID:
24686087
14.

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.

Sun Q, Chen X, Ma J, Peng H, Wang F, Zha X, Wang Y, Jing Y, Yang H, Chen R, Chang L, Zhang Y, Goto J, Onda H, Chen T, Wang MR, Lu Y, You H, Kwiatkowski D, Zhang H.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4129-34. doi: 10.1073/pnas.1014769108. Epub 2011 Feb 15.

15.

Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms.

Taniguchi K, Ito Y, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, Sugiyama T, Futamura M, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.

Sci Rep. 2015 Feb 27;5:8647. doi: 10.1038/srep08647.

16.

Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.

Iqbal MA, Siddiqui FA, Gupta V, Chattopadhyay S, Gopinath P, Kumar B, Manvati S, Chaman N, Bamezai RN.

Mol Cancer. 2013 Jul 9;12:72. doi: 10.1186/1476-4598-12-72.

17.

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.

Hitosugi T, Kang S, Vander Heiden MG, Chung TW, Elf S, Lythgoe K, Dong S, Lonial S, Wang X, Chen GZ, Xie J, Gu TL, Polakiewicz RD, Roesel JL, Boggon TJ, Khuri FR, Gilliland DG, Cantley LC, Kaufman J, Chen J.

Sci Signal. 2009 Nov 17;2(97):ra73. doi: 10.1126/scisignal.2000431.

18.

PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, Burga LN, Xie J, Jurczak MJ, DePinho RA, Clish CB, Jacks T, Kibbey RG, Wulf GM, Di Vizio D, Mills GB, Cantley LC, Vander Heiden MG.

Cell. 2013 Oct 10;155(2):397-409. doi: 10.1016/j.cell.2013.09.025.

19.

Pyruvate kinase M2 and cancer: an updated assessment.

Iqbal MA, Gupta V, Gopinath P, Mazurek S, Bamezai RN.

FEBS Lett. 2014 Aug 19;588(16):2685-92. doi: 10.1016/j.febslet.2014.04.011. Epub 2014 Apr 18. Review.

PMID:
24747424
20.

Estradiol-17β upregulates pyruvate kinase M2 expression to coactivate estrogen receptor-α and to integrate metabolic reprogramming with the mitogenic response in endometrial cells.

Salama SA, Mohammad MA, Diaz-Arrastia CR, Kamel MW, Kilic GS, Ndofor BT, Abdel-Baki MS, Theiler SK.

J Clin Endocrinol Metab. 2014 Oct;99(10):3790-9. doi: 10.1210/jc.2013-2639. Epub 2014 Jan 28.

PMID:
24471565
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