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Items: 1 to 20 of 97

1.

Biomarkers of organophosphorus (OP) exposures in humans.

Marsillach J, Richter RJ, Kim JH, Stevens RC, MacCoss MJ, Tomazela D, Suzuki SM, Schopfer LM, Lockridge O, Furlong CE.

Neurotoxicology. 2011 Oct;32(5):656-60. doi: 10.1016/j.neuro.2011.06.005. Epub 2011 Jul 8.

2.

Quantitation of ortho-cresyl phosphate adducts to butyrylcholinesterase in human serum by immunomagnetic-UHPLC-MS/MS.

Johnson D, Carter MD, Crow BS, Isenberg SL, Graham LA, Erol HA, Watson CM, Pantazides BG, van der Schans MJ, Langenberg JP, Noort D, Blake TA, Thomas JD, Johnson RC.

J Mass Spectrom. 2015 Apr;50(4):683-92. doi: 10.1002/jms.3576.

PMID:
26149113
3.

Identification and characterization of biomarkers of organophosphorus exposures in humans.

Kim JH, Stevens RC, MacCoss MJ, Goodlett DR, Scherl A, Richter RJ, Suzuki SM, Furlong CE.

Adv Exp Med Biol. 2010;660:61-71. doi: 10.1007/978-1-60761-350-3_7. Review.

4.

Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis.

Carletti E, Schopfer LM, Colletier JP, Froment MT, Nachon F, Weik M, Lockridge O, Masson P.

Chem Res Toxicol. 2011 Jun 20;24(6):797-808. doi: 10.1021/tx100447k. Epub 2011 Apr 18.

5.

Cresyl saligenin phosphate makes multiple adducts on free histidine, but does not form an adduct on histidine 438 of human butyrylcholinesterase.

Liyasova MS, Schopfer LM, Lockridge O.

Chem Biol Interact. 2013 Mar 25;203(1):103-7. doi: 10.1016/j.cbi.2012.07.006. Epub 2012 Aug 8.

6.

Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndrome.

Schopfer LM, Masson P, Lamourette P, Simon S, Lockridge O.

Anal Biochem. 2014 Sep 15;461:17-26. doi: 10.1016/j.ab.2014.05.021. Epub 2014 Jun 2.

7.

Protein adducts as biomarkers of exposure to organophosphorus compounds.

Marsillach J, Costa LG, Furlong CE.

Toxicology. 2013 May 10;307:46-54. doi: 10.1016/j.tox.2012.12.007. Epub 2012 Dec 20. Review.

8.

Development of diagnostics in the search for an explanation of aerotoxic syndrome.

Schopfer LM, Furlong CE, Lockridge O.

Anal Biochem. 2010 Sep 1;404(1):64-74. doi: 10.1016/j.ab.2010.04.032. Epub 2010 May 4.

9.

Healthy F-16 pilots show no evidence of exposure to tri-ortho-cresyl phosphate through the on-board oxygen generating system.

Tacal O, Schopfer LM.

Chem Biol Interact. 2014 May 25;215:69-74. doi: 10.1016/j.cbi.2014.03.004. Epub 2014 Mar 22.

PMID:
24661946
10.

Detectable organophosphorus pesticide exposure in the blood of Nebraska and Iowa residents measured by mass spectrometry of butyrylcholinesterase adducts.

Jiang W, Lockridge O.

Chem Biol Interact. 2013 Mar 25;203(1):91-5. doi: 10.1016/j.cbi.2012.09.002. Epub 2012 Sep 16.

PMID:
22989774
11.

Identifying safer anti-wear triaryl phosphate additives for jet engine lubricants.

Baker PE, Cole TB, Cartwright M, Suzuki SM, Thummel KE, Lin YS, Co AL, Rettie AE, Kim JH, Furlong CE.

Chem Biol Interact. 2013 Mar 25;203(1):257-64. doi: 10.1016/j.cbi.2012.10.005. Epub 2012 Oct 22.

12.

Small-scale purification of butyrylcholinesterase from human plasma and implementation of a ╬╝LC-UV/ESI MS/MS method to detect its organophosphorus adducts.

John H, Breyer F, Schmidt C, Mizaikoff B, Worek F, Thiermann H.

Drug Test Anal. 2015 Oct;7(10):947-56. doi: 10.1002/dta.1792. Epub 2015 Mar 31.

PMID:
25828536
13.

Exposure to triaryl phosphates: metabolism and biomarkers of exposure.

Furlong CE.

J Biol Phys Chem. 2011;11. doi: 10.4024/28FU11A.jbpc.11.04.

14.

Blood acylpeptide hydrolase activity is a sensitive marker for exposure to some organophosphate toxicants.

Quistad GB, Klintenberg R, Casida JE.

Toxicol Sci. 2005 Aug;86(2):291-9. Epub 2005 May 11.

15.

Exposure to tri-o-cresyl phosphate detected in jet airplane passengers.

Liyasova M, Li B, Schopfer LM, Nachon F, Masson P, Furlong CE, Lockridge O.

Toxicol Appl Pharmacol. 2011 Nov 1;256(3):337-47. doi: 10.1016/j.taap.2011.06.016. Epub 2011 Jun 24.

16.

Cresyl saligenin phosphate, an organophosphorus toxicant, makes covalent adducts with histidine, lysine, and tyrosine residues of human serum albumin.

Liyasova MS, Schopfer LM, Lockridge O.

Chem Res Toxicol. 2012 Aug 20;25(8):1752-61. doi: 10.1021/tx300215g. Epub 2012 Jul 26.

17.

Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry.

Carletti E, Colletier JP, Schopfer LM, Santoni G, Masson P, Lockridge O, Nachon F, Weik M.

Chem Res Toxicol. 2013 Feb 18;26(2):280-9. doi: 10.1021/tx3004505. Epub 2013 Feb 5.

PMID:
23339663
18.

Proteomic analysis of adducted butyrylcholinesterase for biomonitoring organophosphorus exposures.

Marsillach J, Hsieh EJ, Richter RJ, MacCoss MJ, Furlong CE.

Chem Biol Interact. 2013 Mar 25;203(1):85-90. doi: 10.1016/j.cbi.2012.10.019. Epub 2012 Nov 2.

19.

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of titanium oxide-enriched peptides for detection of aged organophosphorus adducts on human butyrylcholinesterase.

Jiang W, Murashko EA, Dubrovskii YA, Podolskaya EP, Babakov VN, Mikler J, Nachon F, Masson P, Schopfer LM, Lockridge O.

Anal Biochem. 2013 Aug 15;439(2):132-41. doi: 10.1016/j.ab.2013.04.018. Epub 2013 Apr 25.

PMID:
23624322
20.

Enzyme-linked immunosorbent assay for detection of organophosphorylated butyrylcholinesterase: a biomarker of exposure to organophosphate agents.

Wang L, Du D, Lu D, Lin CT, Smith JN, Timchalk C, Liu F, Wang J, Lin Y.

Anal Chim Acta. 2011 May 5;693(1-2):1-6. doi: 10.1016/j.aca.2011.03.013. Epub 2011 Mar 12.

PMID:
21504805
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