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Results: 1 to 20 of 105

1.

Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes.

Tiano JP, Delghingaro-Augusto V, Le May C, Liu S, Kaw MK, Khuder SS, Latour MG, Bhatt SA, Korach KS, Najjar SM, Prentki M, Mauvais-Jarvis F.

J Clin Invest. 2011 Aug;121(8):3331-42. doi: 10.1172/JCI44564. Epub 2011 Jul 11.

PMID:
21747171
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Molecular mechanisms of estrogen receptors' suppression of lipogenesis in pancreatic β-cells.

Tiano JP, Mauvais-Jarvis F.

Endocrinology. 2012 Jul;153(7):2997-3005. doi: 10.1210/en.2011-1980. Epub 2012 May 7.

PMID:
22564979
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Selective estrogen receptor modulation in pancreatic β-cells and the prevention of type 2 diabetes.

Tiano J, Mauvais-Jarvis F.

Islets. 2012 Mar-Apr;4(2):173-6. doi: 10.4161/isl.19747. Epub 2012 Mar 1.

PMID:
22543247
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Voluntary running exercise prevents β-cell failure in susceptible islets of the Zucker diabetic fatty rat.

Delghingaro-Augusto V, Décary S, Peyot ML, Latour MG, Lamontagne J, Paradis-Isler N, Lacharité-Lemieux M, Akakpo H, Birot O, Nolan CJ, Prentki M, Bergeron R.

Am J Physiol Endocrinol Metab. 2012 Jan 15;302(2):E254-64. doi: 10.1152/ajpendo.00360.2011. Epub 2011 Nov 1.

PMID:
22045312
[PubMed - indexed for MEDLINE]
Free Article
5.

Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival.

Liu S, Le May C, Wong WP, Ward RD, Clegg DJ, Marcelli M, Korach KS, Mauvais-Jarvis F.

Diabetes. 2009 Oct;58(10):2292-302. doi: 10.2337/db09-0257. Epub 2009 Jul 8.

PMID:
19587358
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.

Kilic G, Alvarez-Mercado AI, Zarrouki B, Opland D, Liew CW, Alonso LC, Myers MG Jr, Jonas JC, Poitout V, Kulkarni RN, Mauvais-Jarvis F.

PLoS One. 2014 Feb 3;9(2):e87941. doi: 10.1371/journal.pone.0087941. eCollection 2014.

PMID:
24498408
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.

Tokuyama Y, Sturis J, DePaoli AM, Takeda J, Stoffel M, Tang J, Sun X, Polonsky KS, Bell GI.

Diabetes. 1995 Dec;44(12):1447-57.

PMID:
7589853
[PubMed - indexed for MEDLINE]
8.

Importance of oestrogen receptors to preserve functional β-cell mass in diabetes.

Tiano JP, Mauvais-Jarvis F.

Nat Rev Endocrinol. 2012 Feb 14;8(6):342-51. doi: 10.1038/nrendo.2011.242. Review.

PMID:
22330739
[PubMed - indexed for MEDLINE]
9.

Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass.

Delghingaro-Augusto V, Nolan CJ, Gupta D, Jetton TL, Latour MG, Peshavaria M, Madiraju SR, Joly E, Peyot ML, Prentki M, Leahy J.

Diabetologia. 2009 Jun;52(6):1122-32. doi: 10.1007/s00125-009-1317-8. Epub 2009 Mar 18.

PMID:
19294363
[PubMed - indexed for MEDLINE]
10.

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes.

Jourdan T, Godlewski G, Cinar R, Bertola A, Szanda G, Liu J, Tam J, Han T, Mukhopadhyay B, Skarulis MC, Ju C, Aouadi M, Czech MP, Kunos G.

Nat Med. 2013 Sep;19(9):1132-40. doi: 10.1038/nm.3265. Epub 2013 Aug 18.

PMID:
23955712
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes.

Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV, Biden TJ.

Diabetologia. 2007 Apr;50(4):752-63. Epub 2007 Feb 1.

PMID:
17268797
[PubMed - indexed for MEDLINE]
12.

Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.

Wang MY, Koyama K, Shimabukuro M, Mangelsdorf D, Newgard CB, Unger RH.

Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11921-6.

PMID:
9751766
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Enhanced de novo lipogenesis in the leptin-unresponsive pancreatic islets of prediabetic Zucker diabetic fatty rats: role in the pathogenesis of lipotoxic diabetes.

Zhou YT, Shimabukuro M, Lee Y, Koyama K, Higa M, Ferguson T, Unger RH.

Diabetes. 1998 Dec;47(12):1904-8.

PMID:
9836522
[PubMed - indexed for MEDLINE]
14.

Insulinotropic and antidiabetic effects of 17β-estradiol and the GPR30 agonist G-1 on human pancreatic islets.

Kumar R, Balhuizen A, Amisten S, Lundquist I, Salehi A.

Endocrinology. 2011 Jul;152(7):2568-79. doi: 10.1210/en.2010-1361. Epub 2011 Apr 26.

PMID:
21521748
[PubMed - indexed for MEDLINE]
15.
16.

Automated recognition and quantification of pancreatic islets in Zucker diabetic fatty rats treated with exendin-4.

Kakimoto T, Kimata H, Iwasaki S, Fukunari A, Utsumi H.

J Endocrinol. 2013 Jan 2;216(1):13-20. doi: 10.1530/JOE-12-0456. Print 2013 Jan.

PMID:
23092878
[PubMed - indexed for MEDLINE]
Free Article
17.

Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis.

Wong WP, Tiano JP, Liu S, Hewitt SC, Le May C, Dalle S, Katzenellenbogen JA, Katzenellenbogen BS, Korach KS, Mauvais-Jarvis F.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13057-62. doi: 10.1073/pnas.0914501107. Epub 2010 Jun 29.

PMID:
20616010
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction.

Zmuda EJ, Qi L, Zhu MX, Mirmira RG, Montminy MR, Hai T.

Mol Endocrinol. 2010 Jul;24(7):1423-33. doi: 10.1210/me.2009-0463. Epub 2010 Jun 2.

PMID:
20519332
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6.

Green CD, Olson LK.

Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E640-9. doi: 10.1152/ajpendo.00544.2010. Epub 2011 Jan 25.

PMID:
21266672
[PubMed - indexed for MEDLINE]
Free Article
20.

Syzygium cumini ameliorates insulin resistance and β-cell dysfunction via modulation of PPAR, dyslipidemia, oxidative stress, and TNF-α in type 2 diabetic rats.

Sharma AK, Bharti S, Kumar R, Krishnamurthy B, Bhatia J, Kumari S, Arya DS.

J Pharmacol Sci. 2012;119(3):205-13. Epub 2012 Jun 21.

PMID:
22786584
[PubMed - indexed for MEDLINE]
Free Article
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