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Results: 1 to 20 of 100

1.

VapC toxins from Mycobacterium tuberculosis are ribonucleases that differentially inhibit growth and are neutralized by cognate VapB antitoxins.

Ahidjo BA, Kuhnert D, McKenzie JL, Machowski EE, Gordhan BG, Arcus V, Abrahams GL, Mizrahi V.

PLoS One. 2011;6(6):e21738. doi: 10.1371/journal.pone.0021738. Epub 2011 Jun 29.

PMID:
21738782
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The vapBC operon from Mycobacterium smegmatis is an autoregulated toxin-antitoxin module that controls growth via inhibition of translation.

Robson J, McKenzie JL, Cursons R, Cook GM, Arcus VL.

J Mol Biol. 2009 Jul 17;390(3):353-67. doi: 10.1016/j.jmb.2009.05.006. Epub 2009 May 13.

PMID:
19445953
[PubMed - indexed for MEDLINE]
3.

Growth and translation inhibition through sequence-specific RNA binding by Mycobacterium tuberculosis VapC toxin.

Sharp JD, Cruz JW, Raman S, Inouye M, Husson RN, Woychik NA.

J Biol Chem. 2012 Apr 13;287(16):12835-47. doi: 10.1074/jbc.M112.340109. Epub 2012 Feb 21.

PMID:
22354968
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A VapBC toxin-antitoxin module is a posttranscriptional regulator of metabolic flux in mycobacteria.

McKenzie JL, Robson J, Berney M, Smith TC, Ruthe A, Gardner PP, Arcus VL, Cook GM.

J Bacteriol. 2012 May;194(9):2189-204. doi: 10.1128/JB.06790-11. Epub 2012 Feb 24.

PMID:
22366418
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Toxin-antitoxin vapBC locus participates in formation of the dormant state in Mycobacterium smegmatis.

Demidenok OI, Kaprelyants AS, Goncharenko AV.

FEMS Microbiol Lett. 2014 Mar;352(1):69-77. doi: 10.1111/1574-6968.12380. Epub 2014 Feb 26.

PMID:
24417293
[PubMed - in process]
6.

The PIN-domain ribonucleases and the prokaryotic VapBC toxin-antitoxin array.

Arcus VL, McKenzie JL, Robson J, Cook GM.

Protein Eng Des Sel. 2011 Jan;24(1-2):33-40. doi: 10.1093/protein/gzq081. Epub 2010 Oct 29. Review.

PMID:
21036780
[PubMed - indexed for MEDLINE]
Free Article
7.

VapC-1 of nontypeable Haemophilus influenzae is a ribonuclease.

Daines DA, Wu MH, Yuan SY.

J Bacteriol. 2007 Jul;189(14):5041-8. Epub 2007 May 11.

PMID:
17496075
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry.

McKenzie JL, Duyvestyn JM, Smith T, Bendak K, Mackay J, Cursons R, Cook GM, Arcus VL.

RNA. 2012 Jun;18(6):1267-78. doi: 10.1261/rna.031229.111. Epub 2012 Apr 26.

PMID:
22539524
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Noncognate Mycobacterium tuberculosis toxin-antitoxins can physically and functionally interact.

Zhu L, Sharp JD, Kobayashi H, Woychik NA, Inouye M.

J Biol Chem. 2010 Dec 17;285(51):39732-8. doi: 10.1074/jbc.M110.163105. Epub 2010 Sep 27.

PMID:
20876537
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Preliminary crystallographic analysis of recombinant VapBC-15 toxin-antitoxin complex from Mycobacterium tuberculosis.

Das U, Kumar N, Gourinath S, Srinivasan A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Nov;69(Pt 11):1242-5. doi: 10.1107/S1744309113024822. Epub 2013 Oct 17.

PMID:
24192359
[PubMed - indexed for MEDLINE]
11.

Regulation of the vapBC-1 toxin-antitoxin locus in nontypeable Haemophilus influenzae.

Cline SD, Saleem S, Daines DA.

PLoS One. 2012;7(3):e32199. doi: 10.1371/journal.pone.0032199. Epub 2012 Mar 13.

PMID:
22427824
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ectopic production of VapCs from Enterobacteria inhibits translation and trans-activates YoeB mRNA interferase.

Winther KS, Gerdes K.

Mol Microbiol. 2009 May;72(4):918-30. doi: 10.1111/j.1365-2958.2009.06694.x. Epub 2009 Apr 14.

PMID:
19400780
[PubMed - indexed for MEDLINE]
13.

Structure and proposed activity of a member of the VapBC family of toxin-antitoxin systems. VapBC-5 from Mycobacterium tuberculosis.

Miallau L, Faller M, Chiang J, Arbing M, Guo F, Cascio D, Eisenberg D.

J Biol Chem. 2009 Jan 2;284(1):276-83. doi: 10.1074/jbc.M805061200. Epub 2008 Oct 24.

PMID:
18952600
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

[Characterization of toxin-antitoxin systems in Mycobacterium tuberculosis].

Xian Y, Cui L, Zhang J.

Wei Sheng Wu Xue Bao. 2011 Feb;51(2):214-23. Chinese.

PMID:
21574383
[PubMed - indexed for MEDLINE]
15.

Toxin-antitoxin systems of Mycobacterium smegmatis are essential for cell survival.

Frampton R, Aggio RB, Villas-Bôas SG, Arcus VL, Cook GM.

J Biol Chem. 2012 Feb 17;287(8):5340-56. doi: 10.1074/jbc.M111.286856. Epub 2011 Dec 23.

PMID:
22199354
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg²⁺ ion in the active site and a putative RNA-binding site.

Min AB, Miallau L, Sawaya MR, Habel J, Cascio D, Eisenberg D.

Protein Sci. 2012 Nov;21(11):1754-67. doi: 10.1002/pro.2161.

PMID:
23011806
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA.

Winther KS, Gerdes K.

Proc Natl Acad Sci U S A. 2011 May 3;108(18):7403-7. doi: 10.1073/pnas.1019587108. Epub 2011 Apr 18.

PMID:
21502523
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Characterization of a chromosomal toxin-antitoxin, Rv1102c-Rv1103c system in Mycobacterium tuberculosis.

Han JS, Lee JJ, Anandan T, Zeng M, Sripathi S, Jahng WJ, Lee SH, Suh JW, Kang CM.

Biochem Biophys Res Commun. 2010 Sep 24;400(3):293-8. doi: 10.1016/j.bbrc.2010.08.023. Epub 2010 Aug 10.

PMID:
20705052
[PubMed - indexed for MEDLINE]
19.

Regulation of enteric vapBC transcription: induction by VapC toxin dimer-breaking.

Winther KS, Gerdes K.

Nucleic Acids Res. 2012 May;40(10):4347-57. doi: 10.1093/nar/gks029. Epub 2012 Jan 27.

PMID:
22287572
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The Yersinia pestis chromosome encodes active addiction toxins.

Goulard C, Langrand S, Carniel E, Chauvaux S.

J Bacteriol. 2010 Jul;192(14):3669-77. doi: 10.1128/JB.00336-10. Epub 2010 May 14.

PMID:
20472800
[PubMed - indexed for MEDLINE]
Free PMC Article

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