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Results: 1 to 20 of 110

1.

Drug interaction potential of toremifene and N-desmethyltoremifene with multiple cytochrome P450 isoforms.

Kim J, Peraire C, Solà J, Johanning KM, Dalton JT, Veverka KA.

Xenobiotica. 2011 Oct;41(10):851-62. doi: 10.3109/00498254.2011.590546. Epub 2011 Jul 5.

PMID:
21726172
[PubMed - indexed for MEDLINE]
2.

In vitro inhibition and induction of human liver cytochrome p450 enzymes by milnacipran.

Paris BL, Ogilvie BW, Scheinkoenig JA, Ndikum-Moffor F, Gibson R, Parkinson A.

Drug Metab Dispos. 2009 Oct;37(10):2045-54. doi: 10.1124/dmd.109.028274. Epub 2009 Jul 16.

PMID:
19608694
[PubMed - indexed for MEDLINE]
Free Article
3.

In vitro evaluation of the interaction potential of irosustat with drug-metabolizing enzymes.

Ventura V, Solà J, Peraire C, Brée F, Obach R.

Drug Metab Dispos. 2012 Jul;40(7):1268-78. doi: 10.1124/dmd.111.044271. Epub 2012 Mar 26.

PMID:
22451700
[PubMed - indexed for MEDLINE]
Free Article
4.

In vitro assessment of cytochrome P450 inhibition and induction potential of tanespimycin and its major metabolite, 17-amino-17-demethoxygeldanamycin.

Gan J, Liu-Kreyche P, Humphreys WG.

Cancer Chemother Pharmacol. 2012 Jan;69(1):51-6. doi: 10.1007/s00280-011-1672-2. Epub 2011 May 19.

PMID:
21594721
[PubMed - indexed for MEDLINE]
5.

In vitro characterization of the metabolic pathways and cytochrome P450 inhibition and induction potential of BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor.

Hong H, Su H, Ma L, Yao M, Iyer RA, Humphreys WG, Christopher LJ.

Drug Metab Dispos. 2011 Sep;39(9):1658-67. doi: 10.1124/dmd.111.039776. Epub 2011 Jun 14.

PMID:
21673131
[PubMed - indexed for MEDLINE]
Free Article
6.

In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies.

Wang L, Zhang D, Raghavan N, Yao M, Ma L, Frost CE, Maxwell BD, Chen SY, He K, Goosen TC, Humphreys WG, Grossman SJ.

Drug Metab Dispos. 2010 Mar;38(3):448-58. doi: 10.1124/dmd.109.029694. Epub 2009 Nov 25. Erratum in: Drug Metab Dispos. 2010 May;38(5):887. Frost, Charles A [corrected to Frost, Charles E].

PMID:
19940026
[PubMed - indexed for MEDLINE]
Free Article
7.

In vitro studies investigating the interactions between degarelix, a decapeptide gonadotropin-releasing hormone blocker, and cytochrome P450.

Sonesson A, Rasmussen BB.

Basic Clin Pharmacol Toxicol. 2011 Sep;109(3):195-202. doi: 10.1111/j.1742-7843.2011.00709.x. Epub 2011 May 23.

PMID:
21496210
[PubMed - indexed for MEDLINE]
8.

In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine.

Chen Y, Liu L, Laille E, Kumar G, Surapaneni S.

Cancer Chemother Pharmacol. 2010 Apr;65(5):995-1000. doi: 10.1007/s00280-010-1245-9. Epub 2010 Jan 30.

PMID:
20119716
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

In vitro assessment of cytochrome P450 inhibition and induction potential of felotaxel (SHR110008).

Ding Y, Jia Y, Lu C, Liu W, Yang J, Song Y, Zhu Y, Yang L, Ding L, Wen A.

Biomed Pharmacother. 2012 Jun;66(4):318-21. doi: 10.1016/j.biopha.2012.01.001. Epub 2012 Feb 17.

PMID:
22397757
[PubMed - indexed for MEDLINE]
10.

The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.

Parkinson A, Mudra DR, Johnson C, Dwyer A, Carroll KM.

Toxicol Appl Pharmacol. 2004 Sep 15;199(3):193-209. Review.

PMID:
15364537
[PubMed - indexed for MEDLINE]
11.

Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s.

Styles JA, Davies A, Lim CK, De Matteis F, Stanley LA, White IN, Yuan ZX, Smith LL.

Carcinogenesis. 1994 Jan;15(1):5-9.

PMID:
8293548
[PubMed - indexed for MEDLINE]
12.

Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes.

Berthou F, Dreano Y, Belloc C, Kangas L, Gautier JC, Beaune P.

Biochem Pharmacol. 1994 May 18;47(10):1883-95.

PMID:
8204106
[PubMed - indexed for MEDLINE]
13.

Equally potent inhibitors of cholesterol synthesis in human hepatocytes have distinguishable effects on different cytochrome P450 enzymes.

Cohen LH, van Leeuwen RE, van Thiel GC, van Pelt JF, Yap SH.

Biopharm Drug Dispos. 2000 Dec;21(9):353-64.

PMID:
11523064
[PubMed - indexed for MEDLINE]
15.

Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.

Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.

Xenobiotica. 2000 Oct;30(10):955-69.

PMID:
11315104
[PubMed - indexed for MEDLINE]
16.

Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes.

Li T, Li N, Guo Q, Ji H, Zhao D, Xie S, Li X, Qiu Z, Han D, Chen X, You Q.

Eur J Drug Metab Pharmacokinet. 2011 Dec;36(4):249-56. doi: 10.1007/s13318-011-0050-0. Epub 2011 Jun 29.

PMID:
21713461
[PubMed - indexed for MEDLINE]
17.

In vitro inhibition and induction of human hepatic cytochrome P450 enzymes by modafinil.

Robertson P, DeCory HH, Madan A, Parkinson A.

Drug Metab Dispos. 2000 Jun;28(6):664-71.

PMID:
10820139
[PubMed - indexed for MEDLINE]
Free Article
18.

Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities.

Doehmer J, Weiss G, McGregor GP, Appel K.

Toxicol In Vitro. 2011 Feb;25(1):21-7. doi: 10.1016/j.tiv.2010.09.001. Epub 2010 Sep 7.

PMID:
20828605
[PubMed - indexed for MEDLINE]
19.

Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions.

Katoh M, Nakajima M, Shimada N, Yamazaki H, Yokoi T.

Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):843-52.

PMID:
10805063
[PubMed - indexed for MEDLINE]
20.

Metabolism of vanoxerine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine, by human cytochrome P450 enzymes.

Cherstniakova SA, Bi D, Fuller DR, Mojsiak JZ, Collins JM, Cantilena LR.

Drug Metab Dispos. 2001 Sep;29(9):1216-20.

PMID:
11502731
[PubMed - indexed for MEDLINE]
Free Article

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