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Items: 1 to 20 of 375

1.

A phase 2 prospective, randomized, double-blind trial comparing the effects of tranexamic acid with ecallantide on blood loss from high-risk cardiac surgery with cardiopulmonary bypass (CONSERV-2 Trial).

Bokesch PM, Szabo G, Wojdyga R, Grocott HP, Smith PK, Mazer CD, Vetticaden S, Wheeler A, Levy JH.

J Thorac Cardiovasc Surg. 2012 May;143(5):1022-9. doi: 10.1016/j.jtcvs.2011.06.001. Epub 2011 Jul 2.

PMID:
21724197
2.

Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.

Dietrich W, Spannagl M, Boehm J, Hauner K, Braun S, Schuster T, Busley R.

Anesth Analg. 2008 Nov;107(5):1469-78. doi: 10.1213/ane.0b013e318182252b.

PMID:
18931201
3.

Tranexamic acid and aprotinin in low- and intermediate-risk cardiac surgery: a non-sponsored, double-blind, randomised, placebo-controlled trial.

Later AF, Maas JJ, Engbers FH, Versteegh MI, Bruggemans EF, Dion RA, Klautz RJ.

Eur J Cardiothorac Surg. 2009 Aug;36(2):322-9. doi: 10.1016/j.ejcts.2008.11.038. Epub 2009 Feb 27.

PMID:
19250838
4.

Coronary artery bypass grafting after aprotinin: are we doing better?

Beckerman Z, Shopen Y, Alon H, Cohen O, Nir RR, Adler Z, Bolotin G.

J Thorac Cardiovasc Surg. 2013 Jan;145(1):243-8. doi: 10.1016/j.jtcvs.2012.09.032. Epub 2012 Oct 13.

PMID:
23072702
5.

Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study.

Elwatidy S, Jamjoom Z, Elgamal E, Zakaria A, Turkistani A, El-Dawlatly A.

Spine (Phila Pa 1976). 2008 Nov 15;33(24):2577-80. doi: 10.1097/BRS.0b013e318188b9c5.

PMID:
19011538
6.

Aprotinin and tranexamic acid for high transfusion risk cardiac surgery.

Wong BI, McLean RF, Fremes SE, Deemar KA, Harrington EM, Christakis GT, Goldman BS.

Ann Thorac Surg. 2000 Mar;69(3):808-16.

PMID:
10750765
7.

Removal of aprotinin from low-dose aprotinin/tranexamic acid antifibrinolytic therapy increases transfusion requirements in cardiothoracic surgery.

Vonk AB, Meesters MI, Schats J, Romijn JW, Jansen EK, Boer C.

Interact Cardiovasc Thorac Surg. 2011 Feb;12(2):135-9. doi: 10.1510/icvts.2010.250936. Epub 2010 Nov 12.

8.

Impact of tranexamic acid vs. aprotinin on blood loss and transfusion requirements after cardiopulmonary bypass: a prospective, randomised, double-blind trial.

Hekmat K, Zimmermann T, Kampe S, Kasper SM, Weber HJ, Geissler HJ, Mehlhorn U.

Curr Med Res Opin. 2004 Jan;20(1):121-6.

PMID:
14741082
9.

Comparison of blood-conservation strategies in cardiac surgery patients at high risk for bleeding.

Nuttall GA, Oliver WC, Ereth MH, Santrach PJ, Bryant SC, Orszulak TA, Schaff HV.

Anesthesiology. 2000 Mar;92(3):674-82.

PMID:
10719945
10.

Which may be effective to reduce blood loss after cardiac operations in cyanotic children: tranexamic acid, aprotinin or a combination?

Bulutcu FS, Ozbek U, Polat B, Yalçin Y, Karaci AR, Bayindir O.

Paediatr Anaesth. 2005 Jan;15(1):41-6.

PMID:
15649162
11.

Tranexamic acid compared with high-dose aprotinin in primary elective heart operations: effects on perioperative bleeding and allogeneic transfusions.

Casati V, Guzzon D, Oppizzi M, Bellotti F, Franco A, Gerli C, Cossolini M, Torri G, Calori G, Benussi S, Alfieri O.

J Thorac Cardiovasc Surg. 2000 Sep;120(3):520-7.

PMID:
10962414
13.

Fibrinolytic inhibitors in off-pump coronary surgery: a prospective, randomized, double-blind TAP study (tranexamic acid, aprotinin, placebo).

Vanek T, Jares M, Fajt R, Straka Z, Jirasek K, Kolesar M, Brucek P, Maly M.

Eur J Cardiothorac Surg. 2005 Oct;28(4):563-8.

PMID:
16125959
14.

[Effects of topical applications of aprotinin and tranexamic acid on blood loss after open heart surgery].

Yasim A, Aşik R, Atahan E.

Anadolu Kardiyol Derg. 2005 Mar;5(1):36-40. Turkish.

15.

Low dose aprotinin and low dose tranexamic acid in elective cardiac surgery with cardiopulmonary bypass.

Waldow T, Krutzsch D, Wils M, Plötze K, Matschke K.

Clin Hemorheol Microcirc. 2009;42(4):269-77. doi: 10.3233/CH-2009-1197.

PMID:
19628892
16.

Tranexamic acid reduces blood loss after off-pump coronary surgery: a prospective, randomized, double-blind, placebo-controlled study.

Wang G, Xie G, Jiang T, Wang Y, Wang W, Ji H, Liu M, Chen L, Li L.

Anesth Analg. 2012 Aug;115(2):239-43. doi: 10.1213/ANE.0b013e3182264a11. Epub 2011 Jul 7.

PMID:
21737704
17.

Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery.

Graham EM, Atz AM, Gillis J, Desantis SM, Haney AL, Deardorff RL, Uber WE, Reeves ST, McGowan FX Jr, Bradley SM, Spinale FG.

J Thorac Cardiovasc Surg. 2012 May;143(5):1069-76. doi: 10.1016/j.jtcvs.2011.08.051. Epub 2011 Nov 9.

18.

The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery.

Karkouti K, Wijeysundera DN, Yau TM, McCluskey SA, Tait G, Beattie WS.

Anesth Analg. 2010 Jan 1;110(1):21-9. doi: 10.1213/ANE.0b013e3181c0ea6d. Epub 2009 Nov 12.

PMID:
19910626
19.

A propensity score case-control comparison of aprotinin and tranexamic acid in high-transfusion-risk cardiac surgery.

Karkouti K, Beattie WS, Dattilo KM, McCluskey SA, Ghannam M, Hamdy A, Wijeysundera DN, Fedorko L, Yau TM.

Transfusion. 2006 Mar;46(3):327-38.

PMID:
16533273
20.

Tranexamic acid reduces blood loss and transfusion in reoperative cardiac surgery.

Dryden PJ, O'Connor JP, Jamieson WR, Reid I, Ansley D, Sadeghi H, Burr LH, Munro AI, Merrick PM.

Can J Anaesth. 1997 Sep;44(9):934-41.

PMID:
9305556
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