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Results: 1 to 20 of 82

1.

Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome.

Jin X, Moskophidis D, Mivechi NF.

Cell Metab. 2011 Jul 6;14(1):91-103. doi: 10.1016/j.cmet.2011.03.025.

PMID:
21723507
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Heat shock factor 1 accelerates hepatocellular carcinoma development by activating nuclear factor-κB/mitogen-activated protein kinase.

Chuma M, Sakamoto N, Nakai A, Hige S, Nakanishi M, Natsuizaka M, Suda G, Sho T, Hatanaka K, Matsuno Y, Yokoo H, Kamiyama T, Taketomi A, Fujii G, Tashiro K, Hikiba Y, Fujimoto M, Asaka M, Maeda S.

Carcinogenesis. 2014 Feb;35(2):272-81. doi: 10.1093/carcin/bgt343. Epub 2013 Oct 15.

PMID:
24130164
[PubMed - indexed for MEDLINE]
3.

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.

Mueller KM, Kornfeld JW, Friedbichler K, Blaas L, Egger G, Esterbauer H, Hasselblatt P, Schlederer M, Haindl S, Wagner KU, Engblom D, Haemmerle G, Kratky D, Sexl V, Kenner L, Kozlov AV, Terracciano L, Zechner R, Schuetz G, Casanova E, Pospisilik JA, Heim MH, Moriggl R.

Hepatology. 2011 Oct;54(4):1398-409. doi: 10.1002/hep.24509.

PMID:
21725989
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance.

Jung DY, Chalasani U, Pan N, Friedline RH, Prosdocimo DA, Nam M, Azuma Y, Maganti R, Yu K, Velagapudi A, O'Sullivan-Murphy B, Sartoretto JL, Jain MK, Cooper MP, Urano F, Kim JK, Gray S.

PLoS One. 2013 Oct 22;8(10):e77851. doi: 10.1371/journal.pone.0077851. eCollection 2013.

PMID:
24167585
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse.

Ueki K, Kondo T, Tseng YH, Kahn CR.

Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10422-7. Epub 2004 Jul 6. Erratum in: Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13710.

PMID:
15240880
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Heat shock factor 1 promotes invasion and metastasis of hepatocellular carcinoma in vitro and in vivo.

Fang F, Chang R, Yang L.

Cancer. 2012 Apr 1;118(7):1782-94. doi: 10.1002/cncr.26482. Epub 2011 Aug 25.

PMID:
22009757
[PubMed - indexed for MEDLINE]
Free Article
7.

Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer.

Friedbichler K, Themanns M, Mueller KM, Schlederer M, Kornfeld JW, Terracciano LM, Kozlov AV, Haindl S, Kenner L, Kolbe T, Mueller M, Snibson KJ, Heim MH, Moriggl R.

Hepatology. 2012 Mar;55(3):941-52. doi: 10.1002/hep.24765. Epub 2012 Jan 13.

PMID:
22031092
[PubMed - indexed for MEDLINE]
8.

Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis.

Larter CZ, Yeh MM, Van Rooyen DM, Brooling J, Ghatora K, Farrell GC.

J Gastroenterol Hepatol. 2012 Feb;27(2):341-50. doi: 10.1111/j.1440-1746.2011.06939.x.

PMID:
21929649
[PubMed - indexed for MEDLINE]
9.

AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.

Viollet B, Guigas B, Leclerc J, Hébrard S, Lantier L, Mounier R, Andreelli F, Foretz M.

Acta Physiol (Oxf). 2009 May;196(1):81-98. doi: 10.1111/j.1748-1716.2009.01970.x. Epub 2009 Feb 19. Review.

PMID:
19245656
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

High-carbohydrate diets induce hepatic insulin resistance to protect the liver from substrate overload.

Agius L.

Biochem Pharmacol. 2013 Feb 1;85(3):306-12. doi: 10.1016/j.bcp.2012.09.019. Epub 2012 Sep 26.

PMID:
23022226
[PubMed - indexed for MEDLINE]
11.

Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.

Dai C, Whitesell L, Rogers AB, Lindquist S.

Cell. 2007 Sep 21;130(6):1005-18.

PMID:
17889646
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

[Can the hyperactivity of lipogenesis cause hepatic steatosis? A role for ChREBP].

Robichon C, Girard J, Postic C.

Med Sci (Paris). 2008 Oct;24(10):841-6. doi: 10.1051/medsci/20082410841. Review. French.

PMID:
18950580
[PubMed - indexed for MEDLINE]
Free Article
13.

Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development.

Mueller KM, Themanns M, Friedbichler K, Kornfeld JW, Esterbauer H, Tuckermann JP, Moriggl R.

Mol Cell Endocrinol. 2012 Sep 25;361(1-2):1-11. doi: 10.1016/j.mce.2012.03.026. Epub 2012 Apr 30. Review.

PMID:
22564914
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.

Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F.

J Clin Invest. 2009 May;119(5):1201-15. doi: 10.1172/JCI37007. Epub 2009 Apr 13.

PMID:
19363290
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance.

Kang HS, Okamoto K, Kim YS, Takeda Y, Bortner CD, Dang H, Wada T, Xie W, Yang XP, Liao G, Jetten AM.

Diabetes. 2011 Jan;60(1):177-88. doi: 10.2337/db10-0628. Epub 2010 Sep 23.

PMID:
20864514
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice.

Wang Q, Jiang L, Wang J, Li S, Yu Y, You J, Zeng R, Gao X, Rui L, Li W, Liu Y.

Hepatology. 2009 Apr;49(4):1166-75. doi: 10.1002/hep.22774.

PMID:
19177596
[PubMed - indexed for MEDLINE]
17.

A new transgenic rat model of hepatic steatosis and the metabolic syndrome.

Qi NR, Wang J, Zidek V, Landa V, Mlejnek P, Kazdová L, Pravenec M, Kurtz TW.

Hypertension. 2005 May;45(5):1004-11. Epub 2005 Apr 4.

PMID:
15809359
[PubMed - indexed for MEDLINE]
Free Article
18.

Mammalian heat shock factor 1 is essential for oocyte meiosis and directly regulates Hsp90alpha expression.

Metchat A, Akerfelt M, Bierkamp C, Delsinne V, Sistonen L, Alexandre H, Christians ES.

J Biol Chem. 2009 Apr 3;284(14):9521-8. doi: 10.1074/jbc.M808819200. Epub 2009 Jan 21.

PMID:
19158073
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Ajoene, a stable garlic by-product, inhibits high fat diet-induced hepatic steatosis and oxidative injury through LKB1-dependent AMPK activation.

Han CY, Ki SH, Kim YW, Noh K, Lee da Y, Kang B, Ryu JH, Jeon R, Kim EH, Hwang SJ, Kim SG.

Antioxid Redox Signal. 2011 Jan 15;14(2):187-202. doi: 10.1089/ars.2010.3190. Epub 2010 Sep 6.

PMID:
20560786
[PubMed - indexed for MEDLINE]
20.

Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice.

Ma KL, Ruan XZ, Powis SH, Chen Y, Moorhead JF, Varghese Z.

Hepatology. 2008 Sep;48(3):770-81. doi: 10.1002/hep.22423.

PMID:
18752326
[PubMed - indexed for MEDLINE]

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