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Results: 1 to 20 of 108

1.

Ostα depletion protects liver from oral bile acid load.

Soroka CJ, Velazquez H, Mennone A, Ballatori N, Boyer JL.

Am J Physiol Gastrointest Liver Physiol. 2011 Sep;301(3):G574-9. doi: 10.1152/ajpgi.00141.2011. Epub 2011 Jun 30.

PMID:
21719738
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis.

Rao A, Haywood J, Craddock AL, Belinsky MG, Kruh GD, Dawson PA.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3891-6. doi: 10.1073/pnas.0712328105. Epub 2008 Feb 21.

PMID:
18292224
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis.

Soroka CJ, Mennone A, Hagey LR, Ballatori N, Boyer JL.

Hepatology. 2010 Jan;51(1):181-90. doi: 10.1002/hep.23265.

PMID:
19902485
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver.

Ballatori N, Fang F, Christian WV, Li N, Hammond CL.

Am J Physiol Gastrointest Liver Physiol. 2008 Jul;295(1):G179-G186. doi: 10.1152/ajpgi.90319.2008. Epub 2008 May 22.

PMID:
18497332
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Molecular mechanisms of altered bile acid homeostasis in organic solute transporter-alpha knockout mice.

Lan T, Haywood J, Rao A, Dawson PA.

Dig Dis. 2011;29(1):18-22. doi: 10.1159/000324124. Epub 2011 Jun 17.

PMID:
21691100
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter.

Dawson PA, Hubbert M, Haywood J, Craddock AL, Zerangue N, Christian WV, Ballatori N.

J Biol Chem. 2005 Feb 25;280(8):6960-8. Epub 2004 Nov 24.

PMID:
15563450
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia.

Ballatori N, Christian WV, Lee JY, Dawson PA, Soroka CJ, Boyer JL, Madejczyk MS, Li N.

Hepatology. 2005 Dec;42(6):1270-9.

PMID:
16317684
[PubMed - indexed for MEDLINE]
8.

Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.

Boyer JL, Trauner M, Mennone A, Soroka CJ, Cai SY, Moustafa T, Zollner G, Lee JY, Ballatori N.

Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1124-30. Epub 2006 Jan 19.

PMID:
16423920
[PubMed - indexed for MEDLINE]
Free Article
9.

Organic solute transporter, OSTalpha-OSTbeta: its role in bile acid transport and cholestasis.

Soroka CJ, Ballatori N, Boyer JL.

Semin Liver Dis. 2010 May;30(2):178-85. doi: 10.1055/s-0030-1253226. Epub 2010 Apr 26. Review.

PMID:
20422499
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.

Zollner G, Wagner M, Moustafa T, Fickert P, Silbert D, Gumhold J, Fuchsbichler A, Halilbasic E, Denk H, Marschall HU, Trauner M.

Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G923-32. Epub 2005 Dec 15.

PMID:
16357057
[PubMed - indexed for MEDLINE]
Free Article
11.

Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids.

Frankenberg T, Rao A, Chen F, Haywood J, Shneider BL, Dawson PA.

Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G912-22. Epub 2005 Dec 15.

PMID:
16357058
[PubMed - indexed for MEDLINE]
Free Article
12.

Adaptive regulation of bile salt transporters in kidney and liver in obstructive cholestasis in the rat.

Lee J, Azzaroli F, Wang L, Soroka CJ, Gigliozzi A, Setchell KD, Kramer W, Boyer JL.

Gastroenterology. 2001 Dec;121(6):1473-84.

PMID:
11729126
[PubMed - indexed for MEDLINE]
13.

Bile acid transporters: structure, function, regulation and pathophysiological implications.

Alrefai WA, Gill RK.

Pharm Res. 2007 Oct;24(10):1803-23. Epub 2007 Apr 3. Review.

PMID:
17404808
[PubMed - indexed for MEDLINE]
14.

Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine.

Weerachayaphorn J, Mennone A, Soroka CJ, Harry K, Hagey LR, Kensler TW, Boyer JL.

Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G925-36. doi: 10.1152/ajpgi.00263.2011. Epub 2012 Feb 16.

PMID:
22345550
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism.

Lan T, Rao A, Haywood J, Kock ND, Dawson PA.

J Hepatol. 2012 Aug;57(2):359-65. doi: 10.1016/j.jhep.2012.03.025. Epub 2012 Apr 25.

PMID:
22542490
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Ostα-/- mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity.

Wheeler SG, Hammond CL, Jornayvaz FR, Samuel VT, Shulman GI, Soroka CJ, Boyer JL, Hinkle PM, Ballatori N.

Am J Physiol Gastrointest Liver Physiol. 2014 Mar 1;306(5):G425-38. doi: 10.1152/ajpgi.00368.2013. Epub 2013 Dec 31.

PMID:
24381083
[PubMed - indexed for MEDLINE]
17.

Pleiotropic functions of the organic solute transporter Ostα-Ostβ.

Ballatori N.

Dig Dis. 2011;29(1):13-7. doi: 10.1159/000324123. Epub 2011 Jun 17. Review.

PMID:
21691099
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Role of breast cancer resistance protein in the adaptive response to cholestasis.

Mennone A, Soroka CJ, Harry KM, Boyer JL.

Drug Metab Dispos. 2010 Oct;38(10):1673-8. doi: 10.1124/dmd.110.034512. Epub 2010 Jul 2.

PMID:
20601550
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Enterobacteria modulate intestinal bile acid transport and homeostasis through apical sodium-dependent bile acid transporter (SLC10A2) expression.

Miyata M, Yamakawa H, Hamatsu M, Kuribayashi H, Takamatsu Y, Yamazoe Y.

J Pharmacol Exp Ther. 2011 Jan;336(1):188-96. doi: 10.1124/jpet.110.171736. Epub 2010 Sep 30.

PMID:
20884752
[PubMed - indexed for MEDLINE]
Free Article
20.

Role of the intestinal bile acid transporters in bile acid and drug disposition.

Dawson PA.

Handb Exp Pharmacol. 2011;(201):169-203. doi: 10.1007/978-3-642-14541-4_4. Review.

PMID:
21103970
[PubMed - indexed for MEDLINE]
Free PMC Article

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