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A TCR transgenic mouse reactive with multiple systemic dimorphic fungi.

Wüthrich M, Hung CY, Gern BH, Pick-Jacobs JC, Galles KJ, Filutowicz HI, Cole GT, Klein BS.

J Immunol. 2011 Aug 1;187(3):1421-31. doi: 10.4049/jimmunol.1100921. Epub 2011 Jun 24.


C-type lectin receptors differentially induce th17 cells and vaccine immunity to the endemic mycosis of North America.

Wang H, LeBert V, Hung CY, Galles K, Saijo S, Lin X, Cole GT, Klein BS, Wüthrich M.

J Immunol. 2014 Feb 1;192(3):1107-19. doi: 10.4049/jimmunol.1302314. Epub 2014 Jan 3.


Tc17 cells mediate vaccine immunity against lethal fungal pneumonia in immune deficient hosts lacking CD4+ T cells.

Nanjappa SG, Heninger E, Wüthrich M, Gasper DJ, Klein BS.

PLoS Pathog. 2012;8(7):e1002771. doi: 10.1371/journal.ppat.1002771. Epub 2012 Jul 19. Erratum in: PLoS Pathog. 2014 Apr;10(4):e1004148.


Inefficient cross-presentation limits the CD8+ T cell response to a subdominant tumor antigen epitope.

Otahal P, Hutchinson SC, Mylin LM, Tevethia MJ, Tevethia SS, Schell TD.

J Immunol. 2005 Jul 15;175(2):700-12.


Limited model antigen expression by transgenic fungi induces disparate fates during differentiation of adoptively transferred T cell receptor transgenic CD4+ T cells: robust activation and proliferation with weak effector function during recall.

Wüthrich M, Ersland K, Pick-Jacobs JC, Gern BH, Frye CA, Sullivan TD, Brennan MB, Filutowicz HI, O'Brien K, Korthauer KD, Schultz-Cherry S, Klein BS.

Infect Immun. 2012 Feb;80(2):787-97. doi: 10.1128/IAI.05326-11. Epub 2011 Nov 28.


Vaccinated C57BL/6 mice develop protective and memory T cell responses to Coccidioides posadasii infection in the absence of interleukin-10.

Hung CY, Castro-Lopez N, Cole GT.

Infect Immun. 2014 Feb;82(2):903-13. doi: 10.1128/IAI.01148-13. Epub 2013 Dec 9.


Interleukin 1 enhances vaccine-induced antifungal T-helper 17 cells and resistance against Blastomyces dermatitidis infection.

Wüthrich M, LeBert V, Galles K, Hu-Li J, Ben-Sasson SZ, Paul WE, Klein BS.

J Infect Dis. 2013 Oct 1;208(7):1175-82. doi: 10.1093/infdis/jit283. Epub 2013 Jun 20.


Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice.

Wüthrich M, Gern B, Hung CY, Ersland K, Rocco N, Pick-Jacobs J, Galles K, Filutowicz H, Warner T, Evans M, Cole G, Klein B.

J Clin Invest. 2011 Feb;121(2):554-68. doi: 10.1172/JCI43984. Epub 2011 Jan 4.


In vivo ligation of CD40 enhances priming against the endogenous tumor antigen and promotes CD8+ T cell effector function in SV40 T antigen transgenic mice.

Staveley-O'Carroll K, Schell TD, Jimenez M, Mylin LM, Tevethia MJ, Schoenberger SP, Tevethia SS.

J Immunol. 2003 Jul 15;171(2):697-707.


Construction and evaluation of a novel recombinant T cell epitope-based vaccine against Coccidioidomycosis.

Hurtgen BJ, Hung CY, Ostroff GR, Levitz SM, Cole GT.

Infect Immun. 2012 Nov;80(11):3960-74. doi: 10.1128/IAI.00566-12. Epub 2012 Sep 4.


Dynamic interplay among monocyte-derived, dermal, and resident lymph node dendritic cells during the generation of vaccine immunity to fungi.

Ersland K, Wüthrich M, Klein BS.

Cell Host Microbe. 2010 Jun 25;7(6):474-87. doi: 10.1016/j.chom.2010.05.010.


In vivo trafficking and immunostimulatory potential of an intranasally-administered primary dendritic cell-based vaccine.

Vilekar P, Awasthi V, Lagisetty P, King C, Shankar N, Awasthi S.

BMC Immunol. 2010 Dec 10;11:60. doi: 10.1186/1471-2172-11-60.

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